Kasper Harpsøe

CV

09/2019 - : Academic Staff, Department of Drug Design and Pharmacology, Faculty of Health and Medical Scineces

Education:

2006: Ph.D., The Danish University of Pharmaceutical Sciences
Title: Computational Studies on Allosteric Modulations of Ionotropic Glutamate Receptors
2001: Master of Science in pharmacy (Cand. Pharm.), The Royal Danish School of Pharmacy
Masters thesis title: Evaluation of MultiSelect and MultiScore - An Evaluation of New Procedures for Predicting Binding Conformation and Binding Affinity

Previous employments:

01/2014 - 08/2015: Post doc, Department of Drug Design and Pharmacology, Faculty of Health and Medical Scineces

03/2012 - 12/2013: Post doc, The Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Scineces

11/2011 – 02/2012: Postdoc, Faculty of Pharmaceutical Sciences, University of Copenhagen

12/2007 - 06/2011: Postdoc, Faculty of Pharmaceutical Sciences, University of Copenhagen

07/2007 – 11/2007: Scientific Assistant, Faculty of Pharmaceutical Sciences, University of Copenhagen

07/2006 – 06/2007: Research Scientist (Post Doc.), Arpida A/S, Department of Structural Chemistry

05/2006 – 06/2006: Scientific Assistant, The Danish University of Pharmaceutical Sciences 

05/2003 – 04/2006: Ph.D. Student, The Danish University of Pharmaceutical Sciences (including three months traineeship at Schrödinger Inc. New York)

02/2002 – 04/2003: Clinical Research Associate, Quintiles AB

11/2001 – 01/2002: Pharmacist (temporary position), The Danish Medicines Agency, Department of Clinical Trials.

Research expertises:

- Binding site identification and characterization
- Docking and binding pose evaluation
- Protein-ligand interactions 
- Conformational analysis 
- Structure-based ligand design
- QSAR
- Sequence analysis
- Homology modeling
- Molecular dynamics
- Prediction of protein-ligand binding energy
- Quantum Chemistry calculations

Primære forskningsområder

Computational chemistry and molecular modeling in drug design - especially within the target areas of GPCRs, G proteins and ligand-gated ion channels.