Kasper Dyrberg Rand

Publikation

Publikationer pr. år 2006 2016 2017 2018 2019 2020

• 75 Tidsskriftartikel
• 3 Bidrag til bog/antologi
• 3 Review
• 2 Konferenceabstrakt til konference
• 1 Mere
  • 1 Konferenceabstrakt i tidsskrift

Publikationer pr. år

Publikationer pr. år

Søgeresultater

• 2020

  Benzisothiazolinone derivatives as potent allosteric monoacylglycerol lipase inhibitors that functionally mimic sulfenylation of regulatory cysteines

  Castelli, R., Scalvini, L., Vacondio, F., Lodola, A., Anselmi, M., Vezzosi, S., Carmi, C., Bassi, M., Ferlenghi, F., Rivara, S., Möller, I. R., Rand, K. D., Daglian, J., Wei, D., Dotsey, E. Y., Ahmed, F., Jung, K-M., Stella, N., Singh, S., Mor, M., & 1 flerePiomelli, D., 13 feb. 2020, I: Journal of Medicinal Chemistry.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • 1,2-benzisothiazoline-3-one 100%
  • Monoacylglycerol Lipases 80%
  • Sulfenylation 76%
  • Endocannabinoid 76%
  • Site-Directed Mutagenesis 53%
  3 Citationer (Scopus)
• 2019

  A post-translational modification of human Norovirus capsid protein attenuates glycan binding

  Mallagaray, A., Creutznacher, R., Dülfer, J., Mayer, P. H. O., Grimm, L. L., Orduña, J. M., Trabjerg, E., Stehle, T., Rand, K. D., Blaum, B. S., Uetrecht, C. & Peters, T., 1 dec. 2019, I: Nature Communications. 10, 1, 14 s., 1320.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • blood groups 100%
  • Norovirus 71%
  • antigens 70%
  • Capsid Proteins 63%
  • Blood Group Antigens 59%
  25 Citationer (Scopus)

  16 Downloads (Pure)

• Circularized and solubility-enhanced MSPs facilitate simple and high-yield production of stable nanodiscs for studies of membrane proteins in solution

  Johansen, N. T., Tidemand, F. G., Nguyen, T. T. T. N., Rand, K. D., Pedersen, M. C. & Arleth, L., maj 2019, I: F E B S Journal. 286, 9, s. 1734-1751

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  • Nanodisc 100%
  • Solubility 74%
  • Membrane Proteins 61%
  • Protein 30%
  • Small Angle Scattering 25%
  8 Citationer (Scopus)

• Conformational dynamics of the human serotonin transporter during substrate and drug binding

  Möller, I. R., Slivacka, M., Nielsen, A. K., Rasmussen, S. G. F., Gether, U., Loland, C. J. & Rand, K. D., 1 dec. 2019, I: Nature Communications. 10, 1, 1687.

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  • serotonin 100%
  • transporter 87%
  • Serotonin Plasma Membrane Transport Proteins 76%
  • Serotonin 67%
  • drugs 61%
  19 Citationer (Scopus)

  24 Downloads (Pure)

• Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) Centroid Data Measured between 3.6 degrees C and 25.4 degrees C for the Fab Fragment of NISTmAb

  Hudgens, J. W., Gallagher, E. S., Karageorgos, I., Anderson, K. W., Huang, R. Y-C., Chen, G., Bou-Assaf, G. M., Espada, A., Chalmers, M. J., Harguindey, E., Zhang, H-M., Walters, B. T., Zhang, J., Venable, J., Steckler, C., Park, I., Brock, A., Lu, X., Pandey, R., Chandramohan, A., & 16 flereAnand, G. S., Nirudodhi, S. N., Sperry, J. B., Rouse, J. C., Carroll, J. A., Rand, K. D., Leurs, U., Weis, D. D., Al-Naqshabandi, M. A., Hageman, T. S., Deredge, D., Wintrode, P. L., Papanastasiou, M., Lambris, J. D., Li, S. & Urata, S., 2 maj 2019, I: Journal of Research of the National Institute of Standards and Technology. 124, 7 s., 124009.

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  2 Citationer (Scopus)

  13 Downloads (Pure)

• Improving the Sequence Coverage of Integral Membrane Proteins during Hydrogen/Deuterium Exchange Mass Spectrometry Experiments

  Möller, I. R., Slivacka, M., Hausner, J., Nielsen, A. K., Pospisilova, E., Merkle, P. S., Liskova, R., Polak, M., Loland, C. J., Kadek, A., Man, P. & Rand, K. D., 3 sep. 2019, I: Analytical Chemistry. 91, 17, s. 10970-10978 9 s.

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  • Deuterium 100%
  • Mass spectrometry 89%
  • Proteins 63%
  • Membranes 58%
  • Hydrogen 55%
  7 Citationer (Scopus)

• Interlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab fragment of NISTmAb

  Hudgens, J. W., Gallagher, E. S., Karageorgos, I., Anderson, K. W., Filliben, J. J., Huang, R. Y-C., Chen, G., Bou-Assaf, G. M., Espada, A., Chalmers, M. J., Harguindey, E., Zhang, H-M., Walters, B. T., Zhang, J., Venable, J. D., Steckler, C., Park, I., Brock, A., Lu, X., Pandey, R. K., & 17 flereChandramohan, A., Anand, G. S., Nirudodhi, S. N., Sperry, J. B., Rouse, J. C., Carroll, J. A., Rand, K. D., Leurs, U., Weis, D. D., Al-Naqshabandi, M. A., Hageman, T. S., Deredge, D., Wintrode, P. L., Papanastasiou, M., Lambris, J. D., Li, S. & Urata, S., 4 jun. 2019, I: Analytical Chemistry. 91, 11, s. 7336-7345

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Deuterium 100%
  • Mass spectrometry 89%
  • Hydrogen 55%
  • Peptides 27%
  • Proteins 19%
  19 Citationer (Scopus)

• Investigating the Conformational Response of the Sortilin Receptor upon Binding Endogenous Peptide- and Protein Ligands by HDX-MS

  Trabjerg, E., Abu-Asad, N., Wan, Z., Kartberg, F., Christensen, S. & Rand, K. D., 2 jul. 2019, I: Structure. 27, 7, s. 1103-1113.e3

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hydrogen Deuterium Exchange-Mass Spectrometry 100%
  • sortilin 96%
  • Ligands 41%
  • Peptides 37%
  • Neurotensin 34%
  8 Citationer (Scopus)

• Molecular architecture of the Jumonji C family histone demethylase KDM5B

  Dorosz, J., Kristensen, L. H., Aduri, N. G., Mirza, O., Lousen, R., Bucciarelli, S., Mehta, V., Sellés-Baiget, S., Solbak, S. M. Ø., Bach, A., Mesa, P., Hernandez, P. A., Montoya, G., Nguyen, T. T. T. N., Rand, K. D., Boesen, T. & Gajhede, M., 1 dec. 2019, I: Scientific Reports. 9, 13 s., 4019.

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  • Histone Demethylases 100%
  • Lysine 66%
  • Histones 64%
  • Electron Microscopy 59%
  • Hydrogen Deuterium Exchange-Mass Spectrometry 58%
  3 Citationer (Scopus)

  57 Downloads (Pure)

• Probing the Dissociation of Protein Complexes by Means of Gas-Phase H/D Exchange Mass Spectrometry

  Mistarz, U. H., Chandler, S. A., Brown, J. M., Benesch, J. L. P. & Rand, K. D., 1 jan. 2019, I: Journal of the American Society for Mass Spectrometry. 13 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hydrogen Deuterium Exchange-Mass Spectrometry 100%
  • Deuterium 70%
  • Deuterium(.) 53%
  • Gases 49%
  • Dissociation 42%
  7 Citationer (Scopus)

• Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments

  Masson, G. R., Burke, J. E., Ahn, N. G., Anand, G. S., Borchers, C., Brier, S., Bou-Assaf, G. M., Engen, J. R., Englander, S. W., Faber, J., Garlish, R., Griffin, P. R., Gross, M. L., Guttman, M., Hamuro, Y., Heck, A. J. R., Houde, D., Iacob, R. E., Jorgensen, T. J. D., Kaltashov, I. A., & 20 flereKlinman, J. P., Konermann, L., Man, P., Mayne, L., Pascal, B. D., Reichmann, D., Skehel, M., Snijder, J., Strutzenberg, T. S., Underbakke, E. S., Wagner, C., Wales, T. E., Walters, B. T., Weis, D. D., Wilson, D. J., Wintrode, P. L., Zhang, Z., Zheng, J., Schriemer, D. C. & Rand, K. D., 1 jul. 2019, I: Nature Methods. 16, 7, s. 595-602

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hydrogen Deuterium Exchange-Mass Spectrometry 100%
  • Deuterium(.) 53%
  • Mass Spectrometry 39%
  • Hydrogen 34%
  • Practice Guidelines 27%
  127 Citationer (Scopus)

  30 Downloads (Pure)

• Structure and Dynamics of a Promiscuous Xanthan Lyase from Paenibacillus nanensis and the Design of Variants with Increased Stability and Activity

  Jensen, P. F., Kadziola, A., Comamala, G., Segura, D. R., Anderson, L., Poulsen, J-C. N., Rasmussen, K. K., Agarwal, S., Sainathan, R. K., Monrad, R. N., Svendsen, A., Nielsen, J. E., Lo Leggio, L. & Rand, K. D., 21 feb. 2019, I: Cell Chemical Biology. 26, 2, s. 191-202.e1-e6 19 s.

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  • xanthan lyase 100%
  • Paenibacillus 68%
  • Mannose 46%
  • Chelating Agent 41%
  • Small Angle X-Ray Scattering 20%
  3 Citationer (Scopus)

• Substrate-Induced Conformational Dynamics of the Dopamine Transporter

  Nielsen, A. K., Moller, I. R., Rasmussen, S. G. F., Rand, K. D. & Loland, C. J., 1 dec. 2019, I: Biophysical Society. Annual Meeting. Abstracts. 116, 3, s. 346A 1 s., 1714-Pos.

  Publikation: Bidrag til tidsskrift › Konferenceabstrakt i tidsskrift › Forskning › peer review

  • Plasma Membrane Neurotransmitter Transport Proteins 100%
  • Dopamine Plasma Membrane Transport Proteins 97%
  • Hydrogen Deuterium Exchange-Mass Spectrometry 44%
  • Dopamine 44%
  • Extracellular Space 29%
  14 Citationer (Scopus)

  17 Downloads (Pure)

• Substrate-induced conformational dynamics of the dopamine transporter

  Nielsen, A. K., Möller, I. R., Wang, Y., Rasmussen, S. G. F., Lindorff-Larsen, K., Rand, K. D. & Loland, C. J., 1 dec. 2019, I: Nature Communications. 10, 14 s., 2714.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • dopamine 100%
  • transporter 92%
  • Plasma Membrane Neurotransmitter Transport Proteins 82%
  • Dopamine Plasma Membrane Transport Proteins 80%
  • Neurotransmitter 72%
  34 Downloads (Pure)

• The First Community-Wide, Comparative Cross-linking Mass Spectrometry Study

  Iacobucci, C., Piotrowski, C., Aebersold, R., Amaral, B. C., Andrews, P. C., Bernfur, K., Borchers, C. H., Brodie, N. I., Bruce, J. E., Cao, Y., Chaignepain, S., Chavez, J. D., Claverol, S., Cox, J., Davis, T. N., Degliesposti, G., Dong, M-Q., Edinger, N., Emanuelsson, C., Gay, M., & 53 flereGomes-Neto, F., Gozzo, F. C., Gutierrez, C. B., Haupt, C., Heck, A. J. R., Herzog, F., Huang, L., Hoopmann, M. R., Kalisman, N., Klykov, O., Kukačka, Z., Liu, F., MacCoss, M. J., Mechtler, K., Mesika, R., Moritz, R. L., Nagaraj, N., Nesati, V., Neves-Fereira, A. G. C., Ninnis, R., Novák, P., O'Reilly, F. J., Pelzing, M., Petrotchenko, E. V., Piersimoni, L., Plasencia, M., Pukala, T. L., Rand, K. D., Rappsilber, J., Reichman, D., Sailer, C., Sarnowski, C. P., Scheltema, R. A., Schmidt, C., Schriemer, D. C., Shi, Y., Skehel, J. M., Slavin, M., Sobott, F., Solis-Mezarino, V., Stephanowitz, H., Stengel, F., Stieger, C. E., Trabjerg, E., Trnka, M. J., Vilaseca, M., Viner, R., Xiang, Y., Yılmaz, Ş., Zelter, A., Ziemianowicz, D. S., Leitner, A. & Sinz, A., 4 jun. 2019, I: Analytical Chemistry. 91, 11, s. 6953-6961

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  • Mass spectrometry 100%
  • Proteins 71%
  • Proteomics 34%
  • Experiments 9%
  40 Citationer (Scopus)

  20 Downloads (Pure)

• Thiol-ene microfluidic chip for performing hydrogen/deuterium exchange of proteins at sub-second timescales

  Svejdal, R. R., Dickinson, E. R., Sticker, D., Kutter, J. P. & Rand, K. D., 15 jan. 2019, I: Analytical Chemistry.

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  • Deuterium 100%
  • Hemoglobin 78%
  • Microfluidics 73%
  • Proteins 63%
  • Amides 63%
  12 Citationer (Scopus)
• 2018

  Conformational analysis of complex protein states by hydrogen/deuterium exchange mass spectrometry (HDX-MS): Challenges and emerging solutions

  Trabjerg, E., Nazari, Z. E. & Rand, K. D., sep. 2018, I: Trends in Analytical Chemistry. 106, s. 125-138

  Publikation: Bidrag til tidsskrift › Review › peer review

  • Deuterium(.) 100%
  • Mass Spectrometry 73%
  • Hydrogen 55%
  • Protein 45%
  • Instrumentation 13%
  31 Citationer (Scopus)

• Glycine Perturbs Local and Global Conformational Flexibility of a Transmembrane Helix

  Högel, P., Götz, A., Kuhne, F., Ebert, M., Stelzer, W., Rand, K. D., Scharnagl, C. & Langosch, D., 27 feb. 2018, I: Biochemistry. 57, 8, s. 1326-1337 12 s.

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  • Glycine 100%
  • Flexibility 78%
  • Kinetics 23%
  • Deuterium 22%
  • Hydrogen Bond 19%
  13 Citationer (Scopus)

• Installation, validation, and application examples of two instrumental setups for gas-phase HDX-MS analysis of peptides and proteins

  Mistarz, U. H. & Rand, K. D., 15 jul. 2018, I: Methods. 144, s. 113-124

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  • Hydrogen Deuterium Exchange-Mass Spectrometry 100%
  • Gases 49%
  • Electrospray Ionization 40%
  • Peptides 37%
  • Peptide 34%
  6 Citationer (Scopus)

• Investigating the utility of minimized sample preparation and high-resolution mass spectrometry for quantification of monoclonal antibody drugs

  Nguyen, T. T. T. N., Mistarz, U. H., Costa, N., Herbet, A., Boquet, D., Becher, F. & Rand, K. D., 10 sep. 2018, I: Journal of Pharmaceutical and Biomedical Analysis. 159, s. 384-392

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  • High Resolution Mass Spectrometry (HRMS) 100%
  • Mass Spectrometry 82%
  • Sample Preparation 77%
  • Monoclonal Antibodies 67%
  • Drug 48%
  6 Citationer (Scopus)

• Side-chain moieties from the N-terminal region of Aβ are Involved in an oligomer-stabilizing network of interactions

  Przygońska, K., Poznański, J., Mistarz, U. H., Rand, K. D. & Dadlez, M., 6 aug. 2018, I: PLoS One. 13, 8, s. 1-25 25 s., e0201761.

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  • Oligomers 100%
  • Peptides 98%
  • peptide 70%
  • moieties 63%
  • Chain 52%
  7 Citationer (Scopus)

  20 Downloads (Pure)

• Structural Dynamics and Catalytic Properties of a Multimodular Xanthanase

  Moroz, O. V., Jensen, P. F., Mcdonald, S. P., Mcgregor, N., Blagova, E., Comamala, G., Segura, D. R., Anderson, L., Vasu, S. M., Rao, V. P., Giger, L., Sørensen, T. H., Monrad, R. N., Svendsen, A., Nielsen, J. E., Henrissat, B., Davies, G. J., Brumer, H., Rand, K. D. & Wilson, K. S., 6 jul. 2018, I: ACS Catalysis. 8, 7, s. 6021-6034

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  • Enzymes 100%
  • Structural dynamics 96%
  • Catalyst Property 75%
  • Calcium 75%
  • Deuterium(.) 52%
  5 Citationer (Scopus)

• Substrate-modulated unwinding of transmembrane helices in the NSS transporter LeuT: Recommended in F1000Prime as being of special significance in its field by F1000 Faculty Member Robert Vandenberg

  Merkle, P. S., Gotfryd, K., Cuendet, M. A., Leth-Espensen, K. Z., Gether, U., Løland, C. J. & Rand, K. D., 2018, I: Science Advances. 4, 5, 12 s., eaar6179.

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  • Plasma Membrane Neurotransmitter Transport Proteins 100%
  • Hydrogen Deuterium Exchange-Mass Spectrometry 89%
  • Structural Models 31%
  • Detergents 27%
  • Phospholipids 23%
  21 Citationer (Scopus)

  55 Downloads (Pure)

• Unusual Self-Assembly of the Recombinant Chlamydia trachomatis Major Outer Membrane Protein-Based Fusion Antigen CTH522 Into Protein Nanoparticles

  Rose, F., Karlsen, K., Jensen, P. R., Jakobsen, R. U., Wood, G. K., Rand, K. D., Godiksen, H., Andersen, P., Follmann, F. & Foged, C., jun. 2018, I: Journal of Pharmaceutical Sciences. 107, 6, s. 1690-1700 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Chlamydia trachomatis omp1 protein 100%
  • Nanoparticles 49%
  • Antigen 46%
  • Membrane Proteins 46%
  • Antigens 35%
  1 Citationer (Scopus)

• UV Photodissociation Mass Spectrometry Accurately Localize Sites of Backbone Deuteration in Peptides

  Mistarz, U. H., Bellina, B., Jensen, P. F., Brown, J. M., Barran, P. E. & Rand, K. D., 16 jan. 2018, I: Analytical Chemistry. 90, 2, s. 1077-1080 4 s.

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  • Photodissociation 100%
  • Deuterium 71%
  • Peptides 65%
  • Mass spectrometry 63%
  • Hydrogen 19%
  15 Citationer (Scopus)

  11 Downloads (Pure)
• 2017

  A Poly-ADP-Ribose Trigger Releases the Auto-Inhibition of a Chromatin Remodeling Oncogene

  Singh, H. R., Nardozza, A. P., Möller, I. R., Knobloch, G., Kistemaker, H. A. V., Hassler, M., Harrer, N., Blessing, C., Eustermann, S., Kotthoff, C., Huet, S., Mueller-Planitz, F., Filippov, D. V., Timinszky, G., Rand, K. D. & Ladurner, A. G., 7 dec. 2017, I: Molecular Cell. 68, 5, s. 860-871.e7

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  • Poly Adenosine Diphosphate Ribose 100%
  • Chromatin Assembly and Disassembly 83%
  • Oncogenes 67%
  • Chromatin 62%
  • Adenosine Triphosphatases 56%
  33 Citationer (Scopus)

• A Two-pronged Binding Mechanism of IgG to the Neonatal Fc Receptor Controls Complex Stability and IgG Serum Half-life

  Jensen, P. F., Schoch, A., Larraillet, V., Hilger, M., Schlothauer, T., Emrich, T. & Rand, K. D., mar. 2017, I: Molecular and Cellular Proteomics. 16, 3, s. 451-456 6 s.

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  • neonatal Fc receptors 100%
  • briakinumab 82%
  • Reaction Half Life 58%
  • Half-Life 54%
  • Immunoglobulin G 46%
  13 Citationer (Scopus)

  63 Downloads (Pure)

• Conformational characterization of nerve growth factor-β reveals that its regulatory pro-part domain stabilizes three loop regions in its mature part

  Trabjerg, E., Kartberg, F., Christensen, S. & Rand, K. D., 6 okt. 2017, I: Journal of Biological Chemistry. 292, 40, s. 16665-16676 12 s.

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  • Nerve Growth Factor 100%
  • Deuterium(.) 83%
  • Hydrogen 46%
  • Glycosylation 46%
  • Tandem Mass Spectrometry 38%
  12 Citationer (Scopus)

• Construct design, production, and characterization of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine

  Singh, S. K., Roeffen, W., Mistarz, U. H., Chourasia, B. K., Yang, F., Rand, K. D., Sauerwein, R. W. & Theisen, M., 31 maj 2017, I: Microbial Cell Factories. 16, 1, 11 s., 97.

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  • Lactococcus lactis 100%
  • Plasmodium falciparum 87%
  • Protein Subunits 83%
  • protein subunits 75%
  • vaccines 62%
  12 Citationer (Scopus)

  87 Downloads (Pure)

• Expression, Purification and Characterization of GMZ2'.10C, a Complex Disulphide-Bonded Fusion Protein Vaccine Candidate against the Asexual and Sexual Life-Stages of the Malaria-Causing Plasmodium falciparum Parasite

  Mistarz, U. H., Singh, S. K., Nguyen, T. T. T. N., Roeffen, W., Yang, F., Lissau, C., Madsen, S. M., Vrang, A., Tiendrebeogo, R. W., Kana, I. H., Sauerwein, R. W., Theisen, M. & Rand, K. D., 1 sep. 2017, I: Pharmaceutical Research. 34, 9, s. 1970-1983 14 s.

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  • Falciparum Malaria 100%
  • Disulfides 90%
  • Parasites 71%
  • Blocking Antibodies 68%
  • Vaccines 64%
  4 Citationer (Scopus)

• Mapping the interactions of selective biochemical probes of antibody conformation by hydrogen-deuterium exchange mass spectrometry

  Leurs, U., Beck, H., Bonnington, L., Lindner, I., Pol, E. & Rand, K. D., 1 jun. 2017, I: ChemBioChem. 18, 11, s. 1016-1021

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  • Hydrogen Deuterium Exchange-Mass Spectrometry 100%
  • Mass Spectrometry 39%
  • Probe 35%
  • Antibodies 32%
  • Surface Plasmon Resonance 24%
  5 Citationer (Scopus)

• The extraordinary thermal stability of EstA from S. islandicus is independent of post translational modifications

  Stiefler-Jensen, D., Schwarz-Linnet, T., de Lichtenberg, C., Nguyen, T. T. T. N., Rand, K. D., Huang, L., She, Q. & Teilum, K., sep. 2017, I: Protein Science. 26, 9, s. 1819-1827 9 s.

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  • Esterases 100%
  • Post Translational Protein Processing 85%
  • Lysine 81%
  • Methylation 75%
  • Hot Temperature 64%
  3 Citationer (Scopus)

• The T-Cell Receptor Can Bind to the Peptide-Bound Major Histocompatibility Complex and Uncomplexed β₂-Microglobulin through Distinct Binding Sites

  Merkle, P. S., Irving, M., Hongjian, S., Ferber, M., Jørgensen, T. J. D., Scholten, K., Luescher, I., Coukos, G., Zoete, V., Cuendet, M. A., Michielin, O. & Rand, K. D., 1 aug. 2017, I: Biochemistry. 56, 30, s. 3945-3961 17 s.

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  • Major Histocompatibility Complex 100%
  • T-Cell Antigen Receptor 99%
  • Deuterium(.) 88%
  • Binding Sites 75%
  • Binding Site 68%
  5 Citationer (Scopus)

• Thiol-ene Monolithic Pepsin Microreactor with a 3D-Printed Interface for Efficient UPLC-MS Peptide Mapping Analyses

  Jönsson, A., Svejdal, R. R., Bøgelund, N., Nguyen, T. T. T. N., Flindt, H., Kutter, J. P., Rand, K. D. & Lafleur, J. P., 18 apr. 2017, I: Analytical Chemistry. 89, 8, s. 4573-4580 8 s.

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  • Peptides 100%
  • Enzymes 87%
  • Proteins 34%
  • Peptide Hydrolases 28%
  • Packed beds 22%
  30 Citationer (Scopus)
• 2016

  Analytical Techniques in the Pharmaceutical Sciences

  Leurs, U., Mistarz, U. H. & Rand, K. D., 2016, Analytical Techniques in the Pharmaceutical Sciences. Müllertz, A., Perrie, Y. & Rades, T. (red.). Springer Publishing Company, s. 253-289 36 s. (Advances in Delivery Science and Technology).

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review

  • Mass Spectrometry 100%
  • Pharmaceutical Preparations 45%
  • Workflow 40%
  • Tandem Mass Spectrometry 40%
  • Hydrogen Deuterium Exchange-Mass Spectrometry 31%

• A novel sensitive sheathless CE-MS device for peptide and protein analysis

  Nguyen, T. T. T. N., Petersen, N. J. & Rand, K. D., 8 jun. 2016. 1 s.

  Publikation: Konferencebidrag › Konferenceabstrakt til konference › Forskning

  • Peptides 100%
  • Equipment and Supplies 93%
  • Bovine Serum Albumin 59%
  • Proteins 57%
  • Synucleins 52%

• A simple sheathless CE-MS interface with a sub-micrometer electrical contact fracture for sensitive analysis of peptide and protein samples

  Nguyen, T. T. T. N., Petersen, N. J. & Rand, K. D., 14 sep. 2016, I: Analytica Chimica Acta. 936, s. 157–167 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Capillary Electrophoresis-Mass Spectrometry 100%
  • Peptide 40%
  • Protein 28%
  • ESI Spectrum 16%
  • Leucine 12%
  21 Citationer (Scopus)

• Conformational Analysis of Proteins in Highly Concentrated Solutions by Dialysis-Coupled Hydrogen/Deuterium Exchange Mass Spectrometry

  Houde, D., Esmail Nazari, Z., Bou-Assaf, G. M., Weiskopf, A. S. & Rand, K. D., apr. 2016, I: Journal of the American Society for Mass Spectrometry. 27, 4, s. 669–676 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hydrogen Deuterium Exchange-Mass Spectrometry 100%
  • Dialysis Solutions 68%
  • Deuterium(.) 53%
  • Mass Spectrometry 39%
  • Dilution 35%
  12 Citationer (Scopus)

• Conformational destabilization of Immunoglobulin G increases the low pH-binding affinity with the Neonatal Fc Receptor

  Walters, B. T., Jensen, P. F., Larraillet, V., Lin, K., Patapoff, T., Schlothauer, T., Rand, K. D. & Zhang, J., 22 jan. 2016, I: Journal of Biological Chemistry. 291, 4, s. 1817-1825 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • neonatal Fc receptors 100%
  • Immunoglobulin G 46%
  • Histidine Residue 35%
  • Affinity Chromatography 29%
  • Surface Plasmon Resonance 29%
  22 Citationer (Scopus)

• Direct coupling of a flow-flow electromembrane extraction probe to LC-MS

  Fuchs, D., Gabel-Jensen, C., Jensen, H., Rand, K. D., Pedersen-Bjergaard, S., Hansen, S. H. & Petersen, N. J., 28 jan. 2016, I: Analytica Chimica Acta. 905, s. 93-99 7 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Probe 100%
  • Valve 66%
  • Methadone 59%
  • Pharmacological Metabolism 31%
  • Metabolic Reaction 28%
  7 Citationer (Scopus)

• Fully Automated Electro Membrane Extraction Autosampler for LC-MS Systems Allowing Soft Extractions for High-Throughput Applications.

  Fuchs, D., Pedersen-Bjergaard, S., Jensen, H., Rand, K. D., Hansen, S. H. & Petersen, N. J., 5 jul. 2016, I: Analytical Chemistry. 88, 13, s. 6797−6804 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Syringes 100%
  • Membranes 90%
  • Throughput 75%
  • Metabolites 24%
  • Metabolism 22%
  9 Citationer (Scopus)

• Gas-phase fragmentation of peptides to increase the spatial resolution of the Hydrogen Exchange Mass Spectrometry experiment

  Jensen, P. F. & Rand, K. D., mar. 2016, Hydrogen Exchange Mass Spectrometry of Proteins: Fundamentals, Methods and Applications. Weis, D. (red.). Wiley, s. 127-148 22 s.

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review

  • Fragmentation 100%
  • Mass Spectrometry 80%
  • Peptide 69%
  • Hydrogen 61%
  • Dissociation 51%

• Hydrogen exchange: A sensitive analytical window into protein conformation and dynamics

  Jensen, P. F. & Rand, K. D., mar. 2016, Hydrogen Exchange Mass Spectrometry of protein: Fundamentals, Methods and Applications. Weis, D. (red.). Wiley, s. 1-17 17 s.

  Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review

  • proteins 100%
  • hydrogen 76%
  • amides 66%
  • polypeptides 66%
  • mass spectroscopy 34%

• Investigating the Role of Artemin Glycosylation

  Danwen, Q., Code, C., Quan, C., Gong, B-J., Arndt, J., Pepinsky, B., Rand, K. D. & Houde, D., 1 jun. 2016, I: Pharmaceutical Research. 33, 6, s. 1383-1398 16 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Glycosylation 100%
  • Hydrogen Deuterium Exchange-Mass Spectrometry 65%
  • Solubility 38%
  • Drug Development 36%
  • Polysaccharides 36%
  5 Citationer (Scopus)

• Probing the Binding Interfaces of Protein Complexes Using Gas-Phase H/D Exchange Mass Spectrometry

  Mistarz, U. H., Brown, J. M., Haselmann, K. F. & Rand, K. D., 2 feb. 2016, I: Structure. 24, 2, s. 310-318 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hydrogen Deuterium Exchange-Mass Spectrometry 100%
  • Carrier Proteins 50%
  • Gases 49%
  • Deuterium 41%
  • Deuterium(.) 39%
  25 Citationer (Scopus)

• Rapid Conformational Analysis of Protein Drugs in Formulation by Hydrogen/Deuterium Exchange Mass Spectrometry (HDX-MS)

  Esmail Nazari, Z., van de Weert, M., Bou-Assaf, G., Houde, D., Weiskopf, A. & Rand, K. D., 1 nov. 2016, I: Journal of Pharmaceutical Sciences. 105, 11, s. 3269–3277 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hydrogen Deuterium Exchange-Mass Spectrometry 100%
  • Drug Compounding 68%
  • Deuterium(.) 53%
  • Solid Phase Extraction 41%
  • Mass Spectrometry 39%
  9 Citationer (Scopus)

• Removal of N-Linked Glycosylations at Acidic pH by PNGase A Facilitates Hydrogen/Deuterium Exchange Mass Spectrometry Analysis of N-Linked Glycoproteins

  Jensen, P. F., Comamala Grau, G., Trelle, M. B., Madsen, J. B., Jorgensen, T. J. D. & Rand, K. D., 20 dec. 2016, I: Analytical Chemistry. 88, 24, s. 12479-12488 10 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  21 Citationer (Scopus)

• The Impact of the ‘Austrian’ Mutation of the Amyloid Precursor Protein Transmembrane Helix is Communicated to the Hinge Region

  Stelzer, W., Scharnagl, C., Leurs, U., Rand, K. D. & Langosch, D., 16 sep. 2016, I: ChemistrySelect. 1, 15, s. 4408-4412 5 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Mutation 100%
  • Cleavage 80%
  • Protein 48%
  • Amide 41%
  • Hydrogen Bond 35%
  6 Citationer (Scopus)
• 2015

  Conformational analysis of large and highly disulfide-stabilized proteins by integrating online electrochemical reduction into an optimized H/D exchange mass spectrometry workflow

  Trabjerg, E., Jakobsen, R. U., Mysling, S., Christensen, S., Jørgensen, T. J. D. & Rand, K. D., 1 sep. 2015, I: Analytical Chemistry. 87, 17, s. 8880–8888 9 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Mass spectrometry 100%
  • Deuterium 83%
  • Proteins 71%
  • Hydrogen 46%
  • Intercellular Signaling Peptides and Proteins 44%
  27 Citationer (Scopus)

• Formation of covalent di-tyrosine dimers in recombinant α-synuclein

  van Maarschalkerweerd, A., Pedersen, MN., Peterson, H., Nilsson, M., Nguyen, TTT., Skamris, T., Rand, K., Vetri, V., Langkilde, AE. & Vestergaard, B., 19 okt. 2015, I: Intrinsically Disordered Proteins. 3, 1, s. 1-12 12 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Synucleins 100%
  • Tyrosine 60%
  • Parkinson Disease 36%
  • Intrinsically Disordered Proteins 32%
  • Recombinant Proteins 21%
  9 Citationer (Scopus)