Publikationer pr. år
Publikationer pr. år
Personlig profil
Aktuel forskning
- Development of multi-stage (asexual and sexual) malaria vaccine candidate.
- VLP technology as a vaccine delivery system.
- Apply the VLP-based antigen delivery platform to produce combination malaria vaccine (using promising antigen targets from liver stage, blood stage and transmission blocking stage).
- Use the VLP-based antigen delivery platform to produce combination vaccine against Japanese Encephalitis Virus (JEV) (using the Envelope protein from major prevalent genotypes and transmission blocking: mosGCTL-7, a C-type lectin protein which plays crucial role in JEV transmission).
- Parasitic genotyping, production of antigens for immunization in small rodents and serological studies.
- Developing robust and reliable bioassays for assessing the efficacy of vaccine clinical trials.
Aktuel forskning
- Development of multi-stage (asexual and sexual) malaria vaccine candidate.
- VLP technology as a vaccine delivery system.
- Apply the VLP-based antigen delivery platform to produce combination malaria vaccine (using promising antigen targets from liver stage, blood stage and transmission blocking stage).
- Use the VLP-based antigen delivery platform to produce combination vaccine against Japanese Encephalitis Virus (JEV) (using the Envelope protein from major prevalent genotypes and transmission blocking: mosGCTL-7, a C-type lectin protein which plays crucial role in JEV transmission).
- Parasitic genotyping, production of antigens for immunization in small rodents and serological studies.
- Developing robust and reliable bioassays for assessing the efficacy of vaccine clinical trials.
Primære forskningsområder
- Infectious diseases
- Vaccine development
Sprogkundskaber
- English
- Hindi
CV
Ekspertise relateret til FN’s Verdensmål
I 2015 blev FN-landende enige om 17 Verdensmål til at standse fattigdom, beskytte planeten og sikre velstand for alle. Denne persons arbejde bidrager til følgende verdensmål:
Emneord
- Det Sundhedsvidenskabelige Fakultet
Fingeraftryk
Dyk ned i forskningsemnerne, hvor Susheel Singh er aktive. Disse emneetiketter kommer fra dennes persons arbejder. Sammen danner de et unikt fingerprint.
- 8 Lignende profiler
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Unravelling the immune signature of Plasmodium falciparum transmission-reducing immunity
Stone, W. J. R., Campo, J. J., Ouédraogo, A. L., Meerstein-Kessel, L., Morlais, I., Da, D., Cohuet, A., Nsango, S., Sutherland, C. J., van de Vegte-Bolmer, M., Siebelink-Stoter, R., van Gemert, G.-J., Graumans, W., Lanke, K., Shandling, A. D., Pablo, J. V., Teng, A. A., Jones, S., de Jong, R. M. & Fabra-García, A. & 14 flere, , 8 feb. 2018, I: Nature Communications. 9, 1, 14 s., 558.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Dynamics of anti-MSP3 and Pfs230 antibody responses and multiplicity of infection in asymptomatic children from southern Ghana
Amoah, L. E., Acquah, F. K., Ayanful-Torgby, R., Oppong, A., Abankwa, J., Obboh, E. K., Singh, S. K. & Theisen, M., 5 jan. 2018, I: Parasites & Vectors. 11, 1, 9 s., 13.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Expression, Purification and Characterization of GMZ2'.10C, a Complex Disulphide-Bonded Fusion Protein Vaccine Candidate against the Asexual and Sexual Life-Stages of the Malaria-Causing Plasmodium falciparum Parasite
Mistarz, U. H., Singh, S. K., Nguyen, T. T. T. N., Roeffen, W., Yang, F., Lissau, C., Madsen, S. M., Vrang, A., Tiendrebeogo, R. W., Kana, I. H., Sauerwein, R. W., Theisen, M. & Rand, K. D., 1 sep. 2017, I: Pharmaceutical Research. 34, 9, s. 1970-1983 14 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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A novel Pfs38 protein complex on the surface of Plasmodium falciparum blood-stage merozoites
Paul, G., Deshmukh, A., Kaur, I., Rathore, S., Dabral, S., Panda, A., Singh, S. K., Mohmmed, A., Theisen, M. & Malhotra, P., 16 feb. 2017, I: Malaria Journal. 16, 1, 15 s., 79.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Naturally acquired antibodies target the glutamate-rich protein on intact merozoites and predict protection against febrile malaria
Kana, I. H., Adu, B., Tiendrebeogo, R. W., Singh, S. K., Dodoo, D. & Theisen, M., 15 feb. 2017, I: The Journal of Infectious Diseases. 215, 4, s. 623-630 8 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Antibody responses to two new Lactococcus lactis-produced recombinant Pfs48/45 and Pfs230 proteins increase with age in malaria patients living in the Central Region of Ghana
Acquah, F. K., Obboh, E. K., Asare, K., Boampong, J. N., Nuvor, S. V., Singh, S. K., Theisen, M., Williamson, K. C. & Amoah, L. E., 1 aug. 2017, I: Malaria Journal. 16, 11 s., 306.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Construct design, production, and characterization of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine
Singh, S. K., Roeffen, W., Mistarz, U. H., Chourasia, B. K., Yang, F., Rand, K. D., Sauerwein, R. W. & Theisen, M., 31 maj 2017, I: Microbial Cell Factories. 16, 1, 11 s., 97.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Improving the malaria transmission-blocking activity of a Plasmodium falciparum 48/45 based vaccine antigen by SpyTag/SpyCatcher mediated virus-like display
Singh, S. K., Thrane, S., Janitzek, C. M., Nielsen, M. A., Theander, T. G., Theisen, M., Salanti, A. & Sander, A. F., 27 jun. 2017, I: Vaccine. 35, 30, s. 3726-3732 7 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review