Jakob Nilsson

Publikation

Publikationer pr. år 2003 2012 2013 2014 2015 2016 2019 2019

• 34 Tidsskriftartikel
• 3 Leder
• 2 Kommentar/debat
• 2 Review

Publikationer pr. år

Publikationer pr. år

Søgeresultater

• 2019

  A Consensus Binding Motif for the PP4 Protein Phosphatase

  Bidragets oversatte titel: Et bindings motiv for PP4 fosfatasen: NAUeki, Y., Kruse, T., Weisser, M. B., Sundell, G. N., Larsen, M. S. Y., Mendez, B. L., Jenkins, N. P., Garvanska, D. H., Cressey, L., Zhang, G., Davey, N., Montoya, G., Ivarsson, Y., Kettenbach, A. N. & Nilsson, J., 19 dec. 2019, I: Molecular Cell.

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  • protein phosphatase 4 100%
  • Phosphoprotein Phosphatases 63%
  • cohesins 22%
  • Phosphorylation 16%
  • X Ray Crystallography 10%
  10 Citationer (Scopus)

• Efficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complex

  Zhang, G., Kruse, T., Guasch Boldú, C., Garvanska, D. H., Coscia, F., Mann, M., Barisic, M. & Nilsson, J., 1 apr. 2019, I: E M B O Journal. 38, 7, e100977.

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  • M Phase Cell Cycle Checkpoints 100%
  • Kinetochores 96%
  • Rod Like Crystal 68%
  • Anaphase 23%
  • Chromosome Segregation 22%
  21 Citationer (Scopus)

• Protein phosphatases in the regulation of mitosis

  Nilsson, J., 1 feb. 2019, I: The Journal of Cell Biology. 218, 2, 15 s., 395.

  Publikation: Bidrag til tidsskrift › Review › peer review

  • Phosphoprotein Phosphatases 100%
  • Mitosis 84%
  • Phosphotransferases 33%
  • Phosphothreonine 22%
  • Phosphoserine 20%
  29 Citationer (Scopus)

• Response to Raaijmakers & Medema

  Zhang, G., Kruse, T., Boldú, C. G., Garvanska, D. H., Coscia, F., Mann, M., Barisic, M. & Nilsson, J., 15 nov. 2019, I: The EMBO Journal. 38, 22, 5 s., e103547.

  Publikation: Bidrag til tidsskrift › Kommentar/debat › Formidling

  1 Citationer (Scopus)

• The RIF1-PP1 Axis Controls Abscission Timing in Human Cells

  Bhowmick, R., Thakur, R. S., Venegas, A. B., Liu, Y., Nilsson, J., Barisic, M. & Hickson, I. D., 1 apr. 2019, I: Current Biology. 29, 7, s. 1232-1242.e5

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  • Protein Phosphatase 1 100%
  • phosphoprotein phosphatase 96%
  • abscission 87%
  • Cytokinesis 58%
  • Aurora 57%
  12 Citationer (Scopus)
• 2018

  Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer

  Coscia, F., Lengyel, E., Duraiswamy, J., Ashcroft, B., Bassani-Sternberg, M., Wierer, M., Johnson, A., Wroblewski, K., Montag, A., Yamada, S. D., López-Méndez, B., Nilsson, J., Mund, A., Mann, M. & Curtis, M., 2018, I: Cell. 175, 1, s. 159-170.e16

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  • Testicular Neoplasms 100%
  • Proteomics 80%
  • Ovarian Neoplasms 79%
  • Immunotherapy 77%
  • Antigen 73%
  48 Citationer (Scopus)

• The closed form of Mad2 is bound to Mad1 and Cdc20 at unattached kinetochores

  Zhang, G. & Nilsson, J., 3 maj 2018, I: Cell Cycle. 17, 9, s. 1087-1091

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  • Kinetochores 100%
  • M Phase Cell Cycle Checkpoints 57%
  • Anaphase 21%
  • Cdc20 Proteins 16%
  • Mad2 Proteins 15%
  5 Citationer (Scopus)

• The Ebola Virus Nucleoprotein Recruits the Host PP2A-B56 Phosphatase to Activate Transcriptional Support Activity of VP30

  Kruse, T., Biedenkopf, N., Hertz, E. P. T., Dietzel, E., Stalmann, G., López-Méndez, B., Davey, N. E., Nilsson, J. & Becker, S., 4 jan. 2018, I: Molecular Cell. 69, 1, s. 136-145 10 s.

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  • Ebolavirus 100%
  • Nucleoproteins 92%
  • Phosphoric Monoester Hydrolases 74%
  • Binding Sites 56%
  • Ebola Hemorrhagic Fever 51%
  32 Citationer (Scopus)
• 2017

  Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling

  Zhang, G., Kruse, T., López-Méndez, B., Sylvestersen, K. B., Garvanska, D. H., Schopper, S., Nielsen, M. L. & Nilsson, J., 12 jun. 2017, I: Nature Communications. 8, 12 s., 15822.

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  • Kinetochores 100%
  • spindles 98%
  • M Phase Cell Cycle Checkpoints 77%
  • assembly 64%
  • phosphorylation 35%
  42 Citationer (Scopus)

  95 Downloads (Pure)

• Distinct kinetics of serine and threonine dephosphorylation are essential for mitosis

  Hein, J. B., Hertz, E. P. T., Garvanska, D. H., Kruse, T. & Nilsson, J., 29 nov. 2017, I: Nature Cell Biology. 19, s. 1433-1440

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  • Threonine 100%
  • Mitosis 88%
  • Serine 86%
  • Anaphase-Promoting Complex-Cyclosome 65%
  • Kinetics 64%
  49 Citationer (Scopus)

• Localization of PP2A-B56 to centromeres in Drosophila

  Hertz, E. P. T. & Nilsson, J., 3 aug. 2017, I: Cell Cycle. 16, 15, s. 1385-1386 2 s.

  Publikation: Bidrag til tidsskrift › Leder › peer review

  1 Citationer (Scopus)
• 2016

  A Conserved Motif Provides Binding Specificity to the PP2A-B56 Phosphatase

  Hertz, E. P. T., Kruse, T., Davey, N. E., López-Méndez, B., Sigurdsson, J. O., Montoya, G., Olsen, J. V. & Nilsson, J., 18 aug. 2016, I: Molecular Cell. 63, 4, s. 686-695 10 s.

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  • Protein Phosphatase 2 100%
  • Phosphoric Monoester Hydrolases 78%
  • Phosphorylation 53%
  • Consensus Sequence 29%
  • Proteins 28%
  102 Citationer (Scopus)

• Conformation-specific anti-Mad2 monoclonal antibodies for the dissection of checkpoint signaling

  Sedgwick, G. G., Larsen, M. S. Y., Lischetti, T., Streicher, W., Jersie-Christensen, R. R., Olsen, J. V. & Nilsson, J., 18 maj 2016, I: mAbs. 8, 4, s. 689-697 9 s.

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  • Anaphase-Promoting Complex-Cyclosome 100%
  • Dissection 58%
  • Monoclonal Antibodies 49%
  • Mad2 Proteins 41%
  • M Phase Cell Cycle Checkpoints 30%
  4 Citationer (Scopus)

• Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early development

  Pedersen, M. T., Kooistra, S. M., Radzisheuskaya, A., Laugesen, A., Johansen, J. V., Hayward, D. G., Nilsson, J., Agger, K. & Helin, K., 15 jul. 2016, I: E M B O Journal. 35, 14, s. 1550-64 15 s.

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  • Cell Self Renewal 100%
  • Histone 85%
  • Embryonic Stem Cells 85%
  • Methylation 72%
  • Maintenance 33%
  51 Citationer (Scopus)

• Interphase APC/C-Cdc20 inhibition by cyclin A2-Cdk2 ensures efficient mitotic entry

  Hein, J. B. & Nilsson, J., 10 mar. 2016, I: Nature Communications. 7, 10 s., 10975.

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  • Cyclin A2 100%
  • Anaphase-Promoting Complex-Cyclosome 90%
  • Interphase 71%
  • entry 65%
  • phosphorylation 28%
  27 Citationer (Scopus)

• Synergistic inhibition of the APC/C by the removal of APC15 in HCT116 cells lacking UBE2C

  Garvanska, D. H., Larsen, M. S. Y. & Nilsson, J., 15 okt. 2016, I: Biology Open. 5, s. 1441-1448

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  • anaphase promoting complex 100%
  • Anaphase-Promoting Complex-Cyclosome 89%
  • M Phase Cell Cycle Checkpoints 81%
  • HCT116 Cells 78%
  • cells 19%
  4 Citationer (Scopus)

• The Spindle Assembly Checkpoint Is Not Essential for Viability of Human Cells with Genetically Lowered APC/C Activity

  Wild, T., Larsen, M. S. Y., Narita, T., Schou, J., Nilsson, J. & Choudhary, C. R., 1 mar. 2016, I: Cell Reports. 14, 8, s. 1829-40 12 s.

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  • Anaphase-Promoting Complex-Cyclosome 100%
  • M Phase Cell Cycle Checkpoints 92%
  • Cell Survival 51%
  • Ablation 39%
  • Reduction 30%
  31 Citationer (Scopus)

• Two functionally distinct kinetochore pools of BubR1 ensure accurate chromosome segregation

  Zhang, G., Mendez, B. L., Sedgwick, G. G. & Nilsson, J., 26 jul. 2016, I: Nature Communications. 7, s. 1-12 12 s., 12256.

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  • Kinetochores 100%
  • spindles 98%
  • Chromosome Segregation 94%
  • chromosomes 93%
  • assembly 64%
  18 Citationer (Scopus)
• 2015

  Bub1/BubR1: swiss army knives at kinetochores

  Nilsson, J., 11 aug. 2015, I: Cell Cycle. 14, 9, s. 2999-3000 2 s.

  Publikation: Bidrag til tidsskrift › Leder › peer review

  1 Citationer (Scopus)

• Can sequestering of mitotic spindle proteins cause aneuploidy? (Comment on DOI 10.1002/bies.201400175)

  Nilsson, J., 1 mar. 2015, I: BioEssays. 37, 3, s. 234 1 s.

  Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning › peer review

• Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint

  Zhang, G., Lischetti, T., Hayward, D. G. & Nilsson, J., 2 jun. 2015, I: Nature Communications. 6, 14 s., 7162.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Kinetochores 100%
  • rods 61%
  • Strength 48%
  • M Phase Cell Cycle Checkpoints 41%
  • spindles 39%
  50 Citationer (Scopus)

• Mps1-Ndc80: one interaction to rule them all

  Nilsson, J., 10 jun. 2015, I: OncoTarget. 6, 19, s. 16822–16823 2 s.

  Publikation: Bidrag til tidsskrift › Leder › peer review

  2 Citationer (Scopus)

• Regulation of mitotic progression by the spindle assembly checkpoint

  Lischetti, T. & Nilsson, J., 2 jan. 2015, I: Molecular & Cellular Oncology. 2, 1, s. e970484

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • M Phase Cell Cycle Checkpoints 100%
  • Kinetochores 96%
  • Spindle Apparatus 91%
  • Microtubules 35%
  • Mad2 Proteins 33%
  30 Citationer (Scopus)

• TopBP1 is required at mitosis to reduce transmission of DNA damage to G1 daughter cells

  Pedersen, R. T., Kruse, T., Nilsson, J., Østergaard, V. H. & Lisby, M., 17 aug. 2015, I: Journal of Cell Biology. 210, 4, s. 565-582 18 s.

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  • Mitosis 100%
  • DNA Damage 88%
  • Chromosome Segregation 83%
  • Genome 45%
  • DNA 37%
  48 Citationer (Scopus)
• 2014

  A direct role of Mad1 in the spindle assembly checkpoint beyond Mad2 kinetochore recruitment

  Kruse, T., Larsen, M. S. Y., Sedgwick, G. G., Sigurdsson, J. O., Streicher, W., Olsen, J. V. & Nilsson, J., mar. 2014, I: E M B O Reports. 15, s. 282-290

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  • M Phase Cell Cycle Checkpoints 100%
  • Kinetochores 96%
  • Mad2 Proteins 33%
  • Protein 30%
  • Anaphase 23%
  25 Citationer (Scopus)

• A minimal number of MELT repeats supports all functions of KNL1 in chromosome segregation

  Zhang, G., Lischetti, T. & Nilsson, J., 15 feb. 2014, I: Journal of Cell Science. 127, s. 871-884

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  • Chromosome Segregation 100%
  • Kinetochores 79%
  • Mitosis 59%
  • Binding Sites 46%
  • Chromosomes 31%
  61 Citationer (Scopus)

• Comprehensive Identification of SUMO2/3 Targets and Their Dynamics during Mitosis

  Schou, J., Kelstrup, C. D., Hayward, D. G., Olsen, J. V. & Nilsson, J., 27 jun. 2014, I: PLOS ONE. 9, 6, s. e100692 10 s.

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  • Protein 100%
  • Mitosis 94%
  • mitosis 92%
  • Proteins 87%
  • Target 81%
  18 Citationer (Scopus)

• Stable MCC binding to the APC/C is required for a functional spindle assembly checkpoint

  Hein, J. B. & Nilsson, J., mar. 2014, I: E M B O Reports. 15, s. 264-272

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  • M Phase Cell Cycle Checkpoints 100%
  • Plate Like Crystal 57%
  • Anaphase 8%
  • Metaphase 7%
  • Chromosomes 5%
  24 Citationer (Scopus)

• The internal Cdc20 binding site in BubR1 facilitates both spindle assembly checkpoint signalling and silencing

  Lischetti, T., Zhang, G., Sedgwick, G. G., Bolanos-Garcia, V. M. & Nilsson, J., dec. 2014, I: Nature Communications. 5, s. 1-12 12 s., 5563.

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  • M Phase Cell Cycle Checkpoints 100%
  • spindles 95%
  • assembly 62%
  • Binding Sites 56%
  • Kinetochores 53%
  29 Citationer (Scopus)
• 2013

  Direct binding between BubR1 and B56-PP2A phosphatase complexes regulate mitotic progression

  Kruse, T., Zhang, G., Larsen, M. S. Y., Lischetti, T., Streicher, W., Nielsen, T. K., Bjørn, S. P. & Nilsson, J., 1 mar. 2013, I: Journal of Cell Science. 126, s. 1086-1092 7 s.

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  • Kinetochores 100%
  • Protein Phosphatase 2 98%
  • Phosphoric Monoester Hydrolases 77%
  • Aurora Kinase B 58%
  • CDC2 Protein Kinase 54%
  128 Citationer (Scopus)

• Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complex

  Sedgwick, G. G., Hayward, D. G., Nilsson, J., Di Fiore, B., Pines, J., Pardo, M. & Yu, L., 23 jan. 2013, I: E M B O Journal. 32, 2, s. 303-314 12 s.

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  • Anaphase-Promoting Complex-Cyclosome 100%
  • Leucine 70%
  • Dipeptide 68%
  • Dimerization 62%
  • M Phase Cell Cycle Checkpoints 46%
  49 Citationer (Scopus)

• The Drosophila Microtubule-Associated Protein Mars Stabilizes Mitotic Spindles by Crosslinking Microtubules through Its N-Terminal Region

  Zhang, G., Beati, H., Nilsson, J. & Wodarz, A., 4 apr. 2013, I: P L o S One. 8, 4, s. e60596 10 s.

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  • Microtubules 100%
  • Mars 95%
  • Drosophila Proteins 93%
  • Drosophilidae 92%
  • mitotic spindle apparatus 81%
  9 Citationer (Scopus)

• Transcriptional intermediary factor 1γ binds to the anaphase-promoting complex/cyclosome and promotes mitosis

  Sedgwick, G. G., Townsend, K., Martin, A., Shimwell, N. J., Grand, R. J. A., Stewart, G. S., Nilsson, J. & Turnell, A. S., 26 sep. 2013, I: Oncogene. 32, 39, s. 4622-4633 12 s.

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  • transcriptional intermediary factor 1 100%
  • Anaphase-Promoting Complex-Cyclosome 79%
  • Mitosis 53%
  • M Phase Cell Cycle Checkpoints 40%
  • Metaphase 16%
  17 Citationer (Scopus)
• 2012

  DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger

  Danielsen, J. M. R., Povlsen, L. K., Villumsen, B. H., Streicher, W., Nilsson, J., Wikström, M., Bekker-Jensen, S. & Mailand, N., apr. 2012, I: Journal of Cell Biology. 197, 2, s. 179-87 9 s.

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  • Sumoylation 100%
  • Zinc Fingers 84%
  • DNA 41%
  • Chromatin 39%
  • Ubiquitination 32%
  91 Citationer (Scopus)

• Looping in on Ndc80 - how does a protein loop at the kinetochore control chromosome segregation?

  Nilsson, J., dec. 2012, I: BioEssays. 34, 12, s. 1070-7 8 s.

  Publikation: Bidrag til tidsskrift › Review › peer review

  • Kinetochores 100%
  • Chromosome Segregation 94%
  • Microtubules 74%
  • Protein Structure 37%
  • Protein 31%
  15 Citationer (Scopus)

• The architecture of the BubR1 tetratricopeptide tandem repeat defines a protein motif underlying mitotic checkpoint-kinetochore communication

  Bolanos-Garcia, V. M., Nilsson, J. & Blundell, T. L., 1 jan. 2012, I: Bioarchitecture. 2, 1, s. 23-27 5 s.

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  • Tetratricopeptide Repeat 100%
  • M Phase Cell Cycle Checkpoints 89%
  • Kinetochores 86%
  • Amino Acid Motifs 84%
  • Tandem Repeat Sequences 84%

• The Ndc80 internal loop is required for recruitment of the Ska complex to establish end-on microtubule attachment to kinetochores

  Zhang, G., Kelstrup, C. D., Hu, X-W., Hansen, M. J. K., Singleton, M. R., Olsen, J. V. & Nilsson, J., 1 jul. 2012, I: Journal of Cell Science. s. 3243-3253 11 s.

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  • Kinetochores 100%
  • Microtubules 74%
  • Chromosome Segregation 37%
  • AAA Domain 21%
  • Mass Spectrometry 13%
  53 Citationer (Scopus)
• 2011

  Cdc20 control of cell fate during prolonged mitotic arrest: do Cdc20 protein levels affect cell fate in response to antimitotic compounds?

  Nilsson, J., dec. 2011, I: BioEssays. 33, 12, s. 903-9 7 s.

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  • Cdc20 Proteins 100%
  • Antimitotic 76%
  • Antimitotic Agents 74%
  • Cell Death 27%
  • Mitosis 25%
  14 Citationer (Scopus)

• Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site

  Bolanos-Garcia, V. M., Lischetti, T., Matak-Vinković, D., Cota, E., Simpson, P. J., Chirgadze, D. Y., Spring, D. R., Robinson, C. V., Nilsson, J. & Blundell, T. L., 9 nov. 2011, I: Structure. 19, 11, s. 1691-700 10 s.

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  • M Phase Cell Cycle Checkpoints 100%
  • Kinetochores 96%
  • Reaction Stoichiometry 59%
  • Binding Sites 56%
  • Binding Site 51%
  54 Citationer (Scopus)
• 2008

  The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction

  Nilsson, J., Yekezare, M., Minshull, J. & Pines, J., 2008, I: Nature Cell Biology. 10, 12, s. 1411-20 9 s.

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  • Anaphase-Promoting Complex-Cyclosome 100%
  • M Phase Cell Cycle Checkpoints 92%
  • Ubiquitination 29%
  • Mad2 Proteins 24%
  • Securin 22%
  224 Citationer (Scopus)
• 2003

  Calibration of a radioactive ink-based stack phantom and its applications in nuclear medicine

  El-Ali, H., Ljungberg, M., Strand, S. E., Palmer, J., Malmgren, L. & Nilsson, J., 1 jan. 2003, I: Cancer Biotherapy and Radiopharmaceuticals. 18, 2, s. 201-207 7 s.

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  • Ink 100%
  • Nuclear Medicine 86%
  • Calibration 77%
  • Radioactivity 37%
  • Single-Photon Emission-Computed Tomography 25%
  13 Citationer (Scopus)