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Substituted 1,8-naphthyridin-2(1H)-ones are superior to thymine in the recognition of adenine in duplex as well as triplex structures
Anne B Eldrup, Caspar Christensen, Gerald Haaima,
Peter E. Nielsen
Transcription, RNA, and Gene Medicine Program
38
Citations (Scopus)
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Medicine & Life Sciences
1,8-naphthyridin-2(1H)-one
100%
Peptide Nucleic Acids
60%
Thymine
55%
Adenine
48%
Hot Temperature
15%
Oligonucleotides
10%
Base Pairing
10%
Nucleic Acids
10%
RNA
7%
DNA
5%
Chemical Compounds
Nucleobase
44%
Thymine
43%
Adenine
37%
Peptide Nucleic Acid
20%
Thermal Stability
10%
Peptide
9%
Oligonucleotide
7%
Nucleic Acid
6%
Modification
4%
Engineering & Materials Science
Peptide Nucleic Acids
88%
Thermodynamic stability
20%
Stabilization
17%
Oligonucleotides
15%
Nucleic acids
14%
RNA
12%
DNA
10%