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Substituted 1,8-naphthyridin-2(1H)-ones are superior to thymine in the recognition of adenine in duplex as well as triplex structures
Anne B Eldrup, Caspar Christensen, Gerald Haaima,
Peter E. Nielsen
Transcription, RNA, and Gene Medicine Program
38
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Chemistry
Nucleobase
100%
Adenine
100%
Thymine
100%
Peptide Nucleic Acid
80%
Thermal Stability
40%
Ribonucleic Acid
20%
DNA
20%
Nucleic Acid
20%
Oligonucleotide
20%
Base
20%
Biochemistry, Genetics and Molecular Biology
Nucleobase
100%
Adenine
100%
Thymine
100%
Peptide Nucleic Acid
80%
Thermostability
40%
Nucleic Acid
20%
RNA
20%
Oligonucleotide
20%
Base Pairing
20%
Pharmacology, Toxicology and Pharmaceutical Science
Nucleic Acid Base
100%
Thymine
100%
Adenine
100%
Peptide Nucleic Acid
80%
Thermostability
40%
Double Stranded DNA
20%
Base
20%
Oligonucleotide
20%
Nucleic Acid
20%
Keyphrases
End-stacking
20%
Preorganization
20%
Modified System
20%
Stack Efficiency
20%
Nucleic Acid Recognition
20%