Single nucleotide polymorphisms

Claus Børsting; Niels Morling

doi:10.1016/b978-0-12-382165-2.00042-8

Single nucleotide polymorphisms

2 Citations (Scopus)

Abstract

Single-nucleotide polymorphisms (SNPs) are the most frequent polymorphisms in the genome. They have a wide range of possible uses in forensic genetics. In this article, the use of SNPs for human identification is discussed. SNPs are very useful markers for relationship testing and for typing of highly degraded DNA, but they lack discriminatory power when a sample contains DNA from more than one individual. The preferred method for SNP typing in forensic laboratories and the two most promising SNP panels developed for human identification are described in detail.

Original language	English
Title of host publication	Encyclopedia of Forensic Sciences
Editors	JA Siegel, S Pekka
Number of pages	6
Publisher	Elsevier
Publication date	Jan 2013
Edition	2
Pages	233-238
Chapter	42
DOIs	https://doi.org/10.1016/b978-0-12-382165-2.00042-8
Publication status	Published - Jan 2013

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abstract = "Single-nucleotide polymorphisms (SNPs) are the most frequent polymorphisms in the genome. They have a wide range of possible uses in forensic genetics. In this article, the use of SNPs for human identification is discussed. SNPs are very useful markers for relationship testing and for typing of highly degraded DNA, but they lack discriminatory power when a sample contains DNA from more than one individual. The preferred method for SNP typing in forensic laboratories and the two most promising SNP panels developed for human identification are described in detail.",

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AB - Single-nucleotide polymorphisms (SNPs) are the most frequent polymorphisms in the genome. They have a wide range of possible uses in forensic genetics. In this article, the use of SNPs for human identification is discussed. SNPs are very useful markers for relationship testing and for typing of highly degraded DNA, but they lack discriminatory power when a sample contains DNA from more than one individual. The preferred method for SNP typing in forensic laboratories and the two most promising SNP panels developed for human identification are described in detail.

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Single nucleotide polymorphisms

Abstract

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