Single nucleotide polymorphisms

TY - ENCYC

T1 - Single nucleotide polymorphisms

AU - Børsting, Claus

AU - Morling, Niels

PY - 2013/1

Y1 - 2013/1

N2 - Single-nucleotide polymorphisms (SNPs) are the most frequent polymorphisms in the genome. They have a wide range of possible uses in forensic genetics. In this article, the use of SNPs for human identification is discussed. SNPs are very useful markers for relationship testing and for typing of highly degraded DNA, but they lack discriminatory power when a sample contains DNA from more than one individual. The preferred method for SNP typing in forensic laboratories and the two most promising SNP panels developed for human identification are described in detail.

AB - Single-nucleotide polymorphisms (SNPs) are the most frequent polymorphisms in the genome. They have a wide range of possible uses in forensic genetics. In this article, the use of SNPs for human identification is discussed. SNPs are very useful markers for relationship testing and for typing of highly degraded DNA, but they lack discriminatory power when a sample contains DNA from more than one individual. The preferred method for SNP typing in forensic laboratories and the two most promising SNP panels developed for human identification are described in detail.

U2 - 10.1016/b978-0-12-382165-2.00042-8

DO - 10.1016/b978-0-12-382165-2.00042-8

M3 - Encyclopedia chapter

SP - 233

EP - 238

BT - Encyclopedia of Forensic Sciences

A2 - Siegel, JA

A2 - Pekka, S

PB - Elsevier

ER -