R package for Sex-of-Parent-specific Transmission Ratio Distortion

Lam Opal Huang (Producer)

    Abstract

    Transmission Ratio Distortion (TRD) is a genetic phenomenon where the two alleles from either parent are not transmitted to the offspring at the expected 1:1 ratio under Mendelian inheritance, leading to spurious signals in genetic association studies. Functions in this package are developed to account for this phenomenon using loglinear model and Transmission Disequilibrium Test (TDT). Some population information can also be calculated.
    Original languageEnglish
    Publication date2015
    Place of PublicationCanada
    Editionv2
    Media of outputWeb
    Publication statusPublished - 2015

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