R package for Sex-of-Parent-specific Transmission Ratio Distortion

Lam Opal Huang (Producent)

    Abstract

    Transmission Ratio Distortion (TRD) is a genetic phenomenon where the two alleles from either parent are not transmitted to the offspring at the expected 1:1 ratio under Mendelian inheritance, leading to spurious signals in genetic association studies. Functions in this package are developed to account for this phenomenon using loglinear model and Transmission Disequilibrium Test (TDT). Some population information can also be calculated.
    OriginalsprogEngelsk
    Publikationsdato2015
    UdgivelsesstedCanada
    Udgavev2
    PublikationsmedierWeb
    StatusUdgivet - 2015

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