MicroRNAs in Drosophila Cancer Models

Moritz Sander; Héctor Herranz

doi:10.1007/978-3-030-23629-8_9

MicroRNAs in Drosophila Cancer Models

Moritz Sander, Héctor Herranz

Morphogenesis and Differentiation Program

5 Citations (Scopus)

Abstract

MiRNAs are post-transcriptional regulators of gene expression which have been implicated in virtually all biological processes. MiRNAs are frequently dysregulated in human cancers. However, the functional consequences of aberrant miRNA levels are not well understood. Drosophila is emerging as an important in vivo tumor model, especially in the identification of novel cancer genes. Here, we review Drosophila studies which functionally dissect the roles of miRNAs in tumorigenesis. Ultimately, these advances help to understand the implications of miRNA dysregulation in human cancers.

Original language	English
Title of host publication	The Drosophila Model in Cancer
Number of pages	17
Volume	1167
Publisher	Springer
Publication date	2019
Pages	157-173
ISBN (Print)	978-3-030-23628-1
ISBN (Electronic)	978-3-030-23629-8
DOIs	https://doi.org/10.1007/978-3-030-23629-8_9
Publication status	Published - 2019

Series	Advances in Experimental Medicine and Biology
Number	1167
ISSN	0065-2598

Keywords

Animal models
Bantam
Cancer
Drosophila
let-7
miR-7
miR-8
miRNAs
Oncogenic cooperation

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/978-3-030-23629-8_9

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KW - Animal models

KW - Bantam

KW - Cancer

KW - Drosophila

KW - let-7

KW - miR-7

KW - miR-8

KW - miRNAs

KW - Oncogenic cooperation

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BT - The Drosophila Model in Cancer

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ER -

MicroRNAs in Drosophila Cancer Models

Abstract

Keywords

UN SDGs

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