TY - JOUR
T1 - Measurement of the incretin hormones
T2 - glucagon-like peptide-1 and glucose-dependent insulinotropic peptide
AU - Kuhre, Rune Ehrenreich
AU - Wewer Albrechtsen, Nicolai Jacob
AU - Hartmann, Bolette
AU - Deacon, Carolyn F.
AU - Holst, Jens Juul
N1 - Copyright © 2015 Elsevier Inc. All rights reserved.
PY - 2015/4/1
Y1 - 2015/4/1
N2 - The two incretin hormones, glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP), are secreted from the gastrointestinal tract in response to meals and contribute to the regulation of glucose homeostasis by increasing insulin secretion. Assessment of plasma concentrations of GLP-1 and GIP is often an important endpoint in both clinical and preclinical studies and, therefore, accurate measurement of these hormones is important. Here, we provide an overview of current approaches for the measurement of the incretin hormones, with particular focus on immunological methods.
AB - The two incretin hormones, glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP), are secreted from the gastrointestinal tract in response to meals and contribute to the regulation of glucose homeostasis by increasing insulin secretion. Assessment of plasma concentrations of GLP-1 and GIP is often an important endpoint in both clinical and preclinical studies and, therefore, accurate measurement of these hormones is important. Here, we provide an overview of current approaches for the measurement of the incretin hormones, with particular focus on immunological methods.
U2 - 10.1016/j.jdiacomp.2014.12.006
DO - 10.1016/j.jdiacomp.2014.12.006
M3 - Journal article
C2 - 25623632
SN - 1056-8727
VL - 29
SP - 445
EP - 450
JO - Journal of Diabetes and its Complications
JF - Journal of Diabetes and its Complications
IS - 3
ER -