Isolated asymptomatic masseter muscle metastasis as first sign of metastatic disease in a patient with known melanoma

Caroline Asirvatham Gjorup; Helle Westergren Hendel; Inge Marie Svane; Lisbet Rosenkrantz Hölmich

doi:10.1016/j.jpra.2016.07.001

Isolated asymptomatic masseter muscle metastasis as first sign of metastatic disease in a patient with known melanoma

Caroline Asirvatham Gjorup^*, Helle Westergren Hendel, Inge Marie Svane, Lisbet Rosenkrantz Hölmich

^*Corresponding author for this work

Department of Clinical Medicine

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Abstract

A 65-year-old woman diagnosed with a nodular melanoma on the right shoulder had a PET/CT scan 13 months later demonstrating a FDG-avid mass in the left masseter muscle, which was asymptomatic and not clinically evident. Pathologic analysis confirmed metastasis of melanoma. Further subcutaneous, intramuscular and bone metastases developed and the patient was treated with surgery and immunotherapy. The patient is in complete-remission with no evident metastases seen on PET/CT 2.5 years after treatment with adoptive cell therapy using tumor-infiltrating lymphocytes (TIL therapy). Asymptomatic skeletal muscle metastases identified with PET/CT can have therapeutic and prognostic implications and a PET/CT scan should be performed as a true whole-body scan.

Original language	English
Journal	J P R A S Open
Volume	10
Pages (from-to)	1-4
Number of pages	4
ISSN	2352-5878
DOIs	https://doi.org/10.1016/j.jpra.2016.07.001
Publication status	Published - 1 Dec 2016

Keywords

FDG PET/CT
Intramuscular
Masseter muscle
Melanoma
Metastatic
T cell therapy

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10.1016/j.jpra.2016.07.001Licence: CC BY-NC-ND

Isolated asymptomatic masseter muscle metastasis as first sign of metastatic disease in a patient with known melanomaFinal published version, 647 KBLicence: CC BY-NC-ND

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title = "Isolated asymptomatic masseter muscle metastasis as first sign of metastatic disease in a patient with known melanoma",

abstract = "A 65-year-old woman diagnosed with a nodular melanoma on the right shoulder had a PET/CT scan 13 months later demonstrating a FDG-avid mass in the left masseter muscle, which was asymptomatic and not clinically evident. Pathologic analysis confirmed metastasis of melanoma. Further subcutaneous, intramuscular and bone metastases developed and the patient was treated with surgery and immunotherapy. The patient is in complete-remission with no evident metastases seen on PET/CT 2.5 years after treatment with adoptive cell therapy using tumor-infiltrating lymphocytes (TIL therapy). Asymptomatic skeletal muscle metastases identified with PET/CT can have therapeutic and prognostic implications and a PET/CT scan should be performed as a true whole-body scan.",

keywords = "FDG PET/CT, Intramuscular, Masseter muscle, Melanoma, Metastatic, T cell therapy",

author = "Gjorup, {Caroline Asirvatham} and Hendel, {Helle Westergren} and Svane, {Inge Marie} and H{\"o}lmich, {Lisbet Rosenkrantz}",

year = "2016",

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doi = "10.1016/j.jpra.2016.07.001",

language = "English",

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journal = "J P R A S Open",

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TY - JOUR

T1 - Isolated asymptomatic masseter muscle metastasis as first sign of metastatic disease in a patient with known melanoma

AU - Gjorup, Caroline Asirvatham

AU - Hendel, Helle Westergren

AU - Svane, Inge Marie

AU - Hölmich, Lisbet Rosenkrantz

PY - 2016/12/1

Y1 - 2016/12/1

N2 - A 65-year-old woman diagnosed with a nodular melanoma on the right shoulder had a PET/CT scan 13 months later demonstrating a FDG-avid mass in the left masseter muscle, which was asymptomatic and not clinically evident. Pathologic analysis confirmed metastasis of melanoma. Further subcutaneous, intramuscular and bone metastases developed and the patient was treated with surgery and immunotherapy. The patient is in complete-remission with no evident metastases seen on PET/CT 2.5 years after treatment with adoptive cell therapy using tumor-infiltrating lymphocytes (TIL therapy). Asymptomatic skeletal muscle metastases identified with PET/CT can have therapeutic and prognostic implications and a PET/CT scan should be performed as a true whole-body scan.

AB - A 65-year-old woman diagnosed with a nodular melanoma on the right shoulder had a PET/CT scan 13 months later demonstrating a FDG-avid mass in the left masseter muscle, which was asymptomatic and not clinically evident. Pathologic analysis confirmed metastasis of melanoma. Further subcutaneous, intramuscular and bone metastases developed and the patient was treated with surgery and immunotherapy. The patient is in complete-remission with no evident metastases seen on PET/CT 2.5 years after treatment with adoptive cell therapy using tumor-infiltrating lymphocytes (TIL therapy). Asymptomatic skeletal muscle metastases identified with PET/CT can have therapeutic and prognostic implications and a PET/CT scan should be performed as a true whole-body scan.

KW - FDG PET/CT

KW - Intramuscular

KW - Masseter muscle

KW - Melanoma

KW - Metastatic

KW - T cell therapy

U2 - 10.1016/j.jpra.2016.07.001

DO - 10.1016/j.jpra.2016.07.001

M3 - Journal article

AN - SCOPUS:84986277924

SN - 2352-5878

VL - 10

SP - 1

EP - 4

JO - J P R A S Open

JF - J P R A S Open

ER -

Isolated asymptomatic masseter muscle metastasis as first sign of metastatic disease in a patient with known melanoma

Abstract

Keywords

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