Isolated asymptomatic masseter muscle metastasis as first sign of metastatic disease in a patient with known melanoma

TY - JOUR

T1 - Isolated asymptomatic masseter muscle metastasis as first sign of metastatic disease in a patient with known melanoma

AU - Gjorup, Caroline Asirvatham

AU - Hendel, Helle Westergren

AU - Svane, Inge Marie

AU - Hölmich, Lisbet Rosenkrantz

PY - 2016/12/1

Y1 - 2016/12/1

N2 - A 65-year-old woman diagnosed with a nodular melanoma on the right shoulder had a PET/CT scan 13 months later demonstrating a FDG-avid mass in the left masseter muscle, which was asymptomatic and not clinically evident. Pathologic analysis confirmed metastasis of melanoma. Further subcutaneous, intramuscular and bone metastases developed and the patient was treated with surgery and immunotherapy. The patient is in complete-remission with no evident metastases seen on PET/CT 2.5 years after treatment with adoptive cell therapy using tumor-infiltrating lymphocytes (TIL therapy). Asymptomatic skeletal muscle metastases identified with PET/CT can have therapeutic and prognostic implications and a PET/CT scan should be performed as a true whole-body scan.

AB - A 65-year-old woman diagnosed with a nodular melanoma on the right shoulder had a PET/CT scan 13 months later demonstrating a FDG-avid mass in the left masseter muscle, which was asymptomatic and not clinically evident. Pathologic analysis confirmed metastasis of melanoma. Further subcutaneous, intramuscular and bone metastases developed and the patient was treated with surgery and immunotherapy. The patient is in complete-remission with no evident metastases seen on PET/CT 2.5 years after treatment with adoptive cell therapy using tumor-infiltrating lymphocytes (TIL therapy). Asymptomatic skeletal muscle metastases identified with PET/CT can have therapeutic and prognostic implications and a PET/CT scan should be performed as a true whole-body scan.

KW - FDG PET/CT

KW - Intramuscular

KW - Masseter muscle

KW - Melanoma

KW - Metastatic

KW - T cell therapy

U2 - 10.1016/j.jpra.2016.07.001

DO - 10.1016/j.jpra.2016.07.001

M3 - Journal article

AN - SCOPUS:84986277924

SN - 2352-5878

VL - 10

SP - 1

EP - 4

JO - J P R A S Open

JF - J P R A S Open

ER -