Genetic sub-structure in western Mediterranean populations revealed by 12 Y-chromosome STR loci

V Rodríguez; Carmen Tomas Mas; J J Sánchez; J A Castro; M M Ramon; A Barbaro; N Morling; A Picornell

doi:10.1007/s00414-008-0302-y

Genetic sub-structure in western Mediterranean populations revealed by 12 Y-chromosome STR loci

V Rodríguez, Carmen Tomas Mas, J J Sánchez, J A Castro, M M Ramon, A Barbaro, N Morling, A Picornell

Section of Forensic Genetics

13 Citations (Scopus)

Abstract

Haplotype and allele frequencies of 12 Y-chromosome short tandem repeat (Y-STR) loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385 a/b, DYS437, DYS438 and DYS439) included in the Powerplex(R) Y System were determined in seven western Mediterranean populations from Valencia, Majorca, Ibiza (eastern Spain), Sicily and three Calabrian provinces (southern Italy). Amongst the 554 males included in the study, 443 different haplotypes were observed of which 372 were only observed once. The other haplotypes were shared by two to seven men. The overall haplotype diversity was 0.9988 +/- 0.0002. These Y-STRs markers showed a low capacity of discrimination (56.3%) in the Ibiza population probably due to genetic drift. Comparisons between the populations studied and other neighbouring populations showed a clear genetic sub-structure in the western Mediterranean area.

Original language	English
Journal	International Journal of Legal Medicine (Print)
Volume	123
Issue number	2
Pages (from-to)	137-41
ISSN	0937-9827
DOIs	https://doi.org/10.1007/s00414-008-0302-y
Publication status	Published - 2008

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10.1007/s00414-008-0302-y

Cite this

@article{e02914f06bcd11de8bc9000ea68e967b,

title = "Genetic sub-structure in western Mediterranean populations revealed by 12 Y-chromosome STR loci",

abstract = "Haplotype and allele frequencies of 12 Y-chromosome short tandem repeat (Y-STR) loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385 a/b, DYS437, DYS438 and DYS439) included in the Powerplex(R) Y System were determined in seven western Mediterranean populations from Valencia, Majorca, Ibiza (eastern Spain), Sicily and three Calabrian provinces (southern Italy). Amongst the 554 males included in the study, 443 different haplotypes were observed of which 372 were only observed once. The other haplotypes were shared by two to seven men. The overall haplotype diversity was 0.9988 +/- 0.0002. These Y-STRs markers showed a low capacity of discrimination (56.3%) in the Ibiza population probably due to genetic drift. Comparisons between the populations studied and other neighbouring populations showed a clear genetic sub-structure in the western Mediterranean area.",

author = "V Rodr{\'i}guez and {Tomas Mas}, Carmen and S{\'a}nchez, {J J} and Castro, {J A} and Ramon, {M M} and A Barbaro and N Morling and A Picornell",

note = "Keywords: Chromosomes, Human, Y; DNA Fingerprinting; Ethnic Groups; Gene Frequency; Genetic Variation; Genetics, Population; Haplotypes; Humans; Male; Mediterranean Region; Polymerase Chain Reaction; Tandem Repeat Sequences",

year = "2008",

doi = "10.1007/s00414-008-0302-y",

language = "English",

volume = "123",

pages = "137--41",

journal = "International Journal of Legal Medicine",

issn = "0937-9827",

publisher = "Springer",

number = "2",

}

TY - JOUR

T1 - Genetic sub-structure in western Mediterranean populations revealed by 12 Y-chromosome STR loci

AU - Rodríguez, V

AU - Tomas Mas, Carmen

AU - Sánchez, J J

AU - Castro, J A

AU - Ramon, M M

AU - Barbaro, A

AU - Morling, N

AU - Picornell, A

N1 - Keywords: Chromosomes, Human, Y; DNA Fingerprinting; Ethnic Groups; Gene Frequency; Genetic Variation; Genetics, Population; Haplotypes; Humans; Male; Mediterranean Region; Polymerase Chain Reaction; Tandem Repeat Sequences

PY - 2008

Y1 - 2008

N2 - Haplotype and allele frequencies of 12 Y-chromosome short tandem repeat (Y-STR) loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385 a/b, DYS437, DYS438 and DYS439) included in the Powerplex(R) Y System were determined in seven western Mediterranean populations from Valencia, Majorca, Ibiza (eastern Spain), Sicily and three Calabrian provinces (southern Italy). Amongst the 554 males included in the study, 443 different haplotypes were observed of which 372 were only observed once. The other haplotypes were shared by two to seven men. The overall haplotype diversity was 0.9988 +/- 0.0002. These Y-STRs markers showed a low capacity of discrimination (56.3%) in the Ibiza population probably due to genetic drift. Comparisons between the populations studied and other neighbouring populations showed a clear genetic sub-structure in the western Mediterranean area.

AB - Haplotype and allele frequencies of 12 Y-chromosome short tandem repeat (Y-STR) loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385 a/b, DYS437, DYS438 and DYS439) included in the Powerplex(R) Y System were determined in seven western Mediterranean populations from Valencia, Majorca, Ibiza (eastern Spain), Sicily and three Calabrian provinces (southern Italy). Amongst the 554 males included in the study, 443 different haplotypes were observed of which 372 were only observed once. The other haplotypes were shared by two to seven men. The overall haplotype diversity was 0.9988 +/- 0.0002. These Y-STRs markers showed a low capacity of discrimination (56.3%) in the Ibiza population probably due to genetic drift. Comparisons between the populations studied and other neighbouring populations showed a clear genetic sub-structure in the western Mediterranean area.

U2 - 10.1007/s00414-008-0302-y

DO - 10.1007/s00414-008-0302-y

M3 - Journal article

C2 - 19066931

SN - 0937-9827

VL - 123

SP - 137

EP - 141

JO - International Journal of Legal Medicine

JF - International Journal of Legal Medicine

IS - 2

ER -