TY - JOUR
T1 - Genetic sub-structure in western Mediterranean populations revealed by 12 Y-chromosome STR loci
AU - Rodríguez, V
AU - Tomas Mas, Carmen
AU - Sánchez, J J
AU - Castro, J A
AU - Ramon, M M
AU - Barbaro, A
AU - Morling, N
AU - Picornell, A
N1 - Keywords: Chromosomes, Human, Y; DNA Fingerprinting; Ethnic Groups; Gene Frequency; Genetic Variation; Genetics, Population; Haplotypes; Humans; Male; Mediterranean Region; Polymerase Chain Reaction; Tandem Repeat Sequences
PY - 2008
Y1 - 2008
N2 - Haplotype and allele frequencies of 12 Y-chromosome short tandem repeat (Y-STR) loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385 a/b, DYS437, DYS438 and DYS439) included in the Powerplex(R) Y System were determined in seven western Mediterranean populations from Valencia, Majorca, Ibiza (eastern Spain), Sicily and three Calabrian provinces (southern Italy). Amongst the 554 males included in the study, 443 different haplotypes were observed of which 372 were only observed once. The other haplotypes were shared by two to seven men. The overall haplotype diversity was 0.9988 +/- 0.0002. These Y-STRs markers showed a low capacity of discrimination (56.3%) in the Ibiza population probably due to genetic drift. Comparisons between the populations studied and other neighbouring populations showed a clear genetic sub-structure in the western Mediterranean area.
AB - Haplotype and allele frequencies of 12 Y-chromosome short tandem repeat (Y-STR) loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385 a/b, DYS437, DYS438 and DYS439) included in the Powerplex(R) Y System were determined in seven western Mediterranean populations from Valencia, Majorca, Ibiza (eastern Spain), Sicily and three Calabrian provinces (southern Italy). Amongst the 554 males included in the study, 443 different haplotypes were observed of which 372 were only observed once. The other haplotypes were shared by two to seven men. The overall haplotype diversity was 0.9988 +/- 0.0002. These Y-STRs markers showed a low capacity of discrimination (56.3%) in the Ibiza population probably due to genetic drift. Comparisons between the populations studied and other neighbouring populations showed a clear genetic sub-structure in the western Mediterranean area.
U2 - 10.1007/s00414-008-0302-y
DO - 10.1007/s00414-008-0302-y
M3 - Journal article
C2 - 19066931
SN - 0937-9827
VL - 123
SP - 137
EP - 141
JO - International Journal of Legal Medicine (Print)
JF - International Journal of Legal Medicine (Print)
IS - 2
ER -