Evaluation of a polyacrylamide hydrogel in the treatment of induced osteoarthritis in a goat model: a randomized controlled pilot study

Aziz Tnibar; Ann Persson; Henrik Elvang Jensen; Eiliv Lars Svalastoga; Ulrik Westrup; Fintan McEvoy; Jes Christian Knudsen; Preben Dybdahl Thomsen; Lise Charlotte Berg; Stine Jacobsen; L.H. Christensen

doi:10.1016/j.joca.2014.02.906

Evaluation of a polyacrylamide hydrogel in the treatment of induced osteoarthritis in a goat model: a randomized controlled pilot study

Aziz Tnibar, Ann Persson, Henrik Elvang Jensen, Eiliv Lars Svalastoga, Ulrik Westrup, Fintan McEvoy, Jes Christian Knudsen, Preben Dybdahl Thomsen, Lise Charlotte Berg, Stine Jacobsen, L.H. Christensen

Dairy Technology

Abstract

Polyacrylamide hydrogel (PAAG) is an inert, non-degradable, non-immunogenic polymer gel with high viscoelasticity consisting of 97.5% sterile water and 2.5% cross-linked polyacrylamide. Its biocompatibility in soft tissues has been demonstrated. PAAG has recently been tested for the treatment of osteoarthritis (OA) in horses with highly encouraging results; however no standardized experimental studies have been done to explore its efficacy. The purpose of this study was to evaluate PAAG in the treatment of induced OA in a goat model

Original language	English
Article number	871
Journal	Osteoarthritis and Cartilage
Volume	22, Supplement
Pages (from-to)	S477
Number of pages	1
ISSN	1063-4584
DOIs	https://doi.org/10.1016/j.joca.2014.02.906
Publication status	Published - 2014
Event	2014- world congress on osteoarthritis -oarsi - Paris, France Duration: 24 Apr 2014 → 27 Apr 2014

Conference

Conference	2014- world congress on osteoarthritis -oarsi
Country/Territory	France
City	Paris
Period	24/04/2014 → 27/04/2014

Keywords

Faculty of Health and Medical Sciences

Access to Document

10.1016/j.joca.2014.02.906

http://www.oarsijournal.com/article/S1063458414009467/pdf

Cite this

Tnibar, A., Persson, A., Jensen, H. E., Svalastoga, E. L., Westrup, U., McEvoy, F., Knudsen, J. C., Thomsen, P. D., Berg, L. C., Jacobsen, S., & Christensen, L. H. (2014). Evaluation of a polyacrylamide hydrogel in the treatment of induced osteoarthritis in a goat model: a randomized controlled pilot study. Osteoarthritis and Cartilage, 22, Supplement, S477. Article 871. https://doi.org/10.1016/j.joca.2014.02.906

Evaluation of a polyacrylamide hydrogel in the treatment of induced osteoarthritis in a goat model: a randomized controlled pilot study. / Tnibar, Aziz; Persson, Ann; Jensen, Henrik Elvang et al.
In: Osteoarthritis and Cartilage, Vol. 22, Supplement, 871, 2014, p. S477.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Tnibar, A, Persson, A, Jensen, HE , Svalastoga, EL , Westrup, U , McEvoy, F, Knudsen, JC, Thomsen, PD , Berg, LC , Jacobsen, S & Christensen, LH 2014, 'Evaluation of a polyacrylamide hydrogel in the treatment of induced osteoarthritis in a goat model: a randomized controlled pilot study', Osteoarthritis and Cartilage, vol. 22, Supplement, 871, pp. S477. https://doi.org/10.1016/j.joca.2014.02.906

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abstract = "Polyacrylamide hydrogel (PAAG) is an inert, non-degradable, non-immunogenic polymer gel with high viscoelasticity consisting of 97.5% sterile water and 2.5% cross-linked polyacrylamide. Its biocompatibility in soft tissues has been demonstrated. PAAG has recently been tested for the treatment of osteoarthritis (OA) in horses with highly encouraging results; however no standardized experimental studies have been done to explore its efficacy. The purpose of this study was to evaluate PAAG in the treatment of induced OA in a goat model",

keywords = "Faculty of Health and Medical Sciences, Goats, Veterinary medicine, Animal Model, joint disease, Osteoarthritis",

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