Evaluation of a polyacrylamide hydrogel in the treatment of induced osteoarthritis in a goat model: a randomized controlled pilot study

Aziz Tnibar; Ann Persson; Henrik Elvang Jensen; Eiliv Lars Svalastoga; Ulrik Westrup; Fintan McEvoy; Jes Christian Knudsen; Preben Dybdahl Thomsen; Lise Charlotte Berg; Stine Jacobsen; L.H. Christensen

doi:10.1016/j.joca.2014.02.906

Evaluation of a polyacrylamide hydrogel in the treatment of induced osteoarthritis in a goat model: a randomized controlled pilot study

Aziz Tnibar, Ann Persson, Henrik Elvang Jensen, Eiliv Lars Svalastoga, Ulrik Westrup, Fintan McEvoy, Jes Christian Knudsen, Preben Dybdahl Thomsen, Lise Charlotte Berg, Stine Jacobsen, L.H. Christensen

Mejeriteknologi

Abstract

Polyacrylamide hydrogel (PAAG) is an inert, non-degradable, non-immunogenic polymer gel with high viscoelasticity consisting of 97.5% sterile water and 2.5% cross-linked polyacrylamide. Its biocompatibility in soft tissues has been demonstrated. PAAG has recently been tested for the treatment of osteoarthritis (OA) in horses with highly encouraging results; however no standardized experimental studies have been done to explore its efficacy. The purpose of this study was to evaluate PAAG in the treatment of induced OA in a goat model

Originalsprog	Engelsk
Artikelnummer	871
Tidsskrift	Osteoarthritis and Cartilage
Vol/bind	22, Supplement
Sider (fra-til)	S477
Antal sider	1
ISSN	1063-4584
DOI	https://doi.org/10.1016/j.joca.2014.02.906
Status	Udgivet - 2014
Begivenhed	2014- world congress on osteoarthritis -oarsi - Paris, Frankrig Varighed: 24 apr. 2014 → 27 apr. 2014

Konference

Konference	2014- world congress on osteoarthritis -oarsi
Land/Område	Frankrig
By	Paris
Periode	24/04/2014 → 27/04/2014

Emneord

Det Sundhedsvidenskabelige Fakultet
Goats
Veterinary medicine
Animal Model
joint disease
Osteoarthritis

Adgang til dokumentet

10.1016/j.joca.2014.02.906

http://www.oarsijournal.com/article/S1063458414009467/pdf

Citationsformater

Tnibar, A., Persson, A., Jensen, H. E., Svalastoga, E. L., Westrup, U., McEvoy, F., Knudsen, J. C., Thomsen, P. D., Berg, L. C., Jacobsen, S., & Christensen, L. H. (2014). Evaluation of a polyacrylamide hydrogel in the treatment of induced osteoarthritis in a goat model: a randomized controlled pilot study. Osteoarthritis and Cartilage, 22, Supplement, S477. Artikel 871. https://doi.org/10.1016/j.joca.2014.02.906

Tnibar, A, Persson, A, Jensen, HE , Svalastoga, EL , Westrup, U , McEvoy, F, Knudsen, JC, Thomsen, PD , Berg, LC , Jacobsen, S & Christensen, LH 2014, 'Evaluation of a polyacrylamide hydrogel in the treatment of induced osteoarthritis in a goat model: a randomized controlled pilot study', Osteoarthritis and Cartilage, bind 22, Supplement, 871, s. S477. https://doi.org/10.1016/j.joca.2014.02.906

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abstract = "Polyacrylamide hydrogel (PAAG) is an inert, non-degradable, non-immunogenic polymer gel with high viscoelasticity consisting of 97.5% sterile water and 2.5% cross-linked polyacrylamide. Its biocompatibility in soft tissues has been demonstrated. PAAG has recently been tested for the treatment of osteoarthritis (OA) in horses with highly encouraging results; however no standardized experimental studies have been done to explore its efficacy. The purpose of this study was to evaluate PAAG in the treatment of induced OA in a goat model",

keywords = "Faculty of Health and Medical Sciences, Goats, Veterinary medicine, Animal Model, joint disease, Osteoarthritis",

author = "Aziz Tnibar and Ann Persson and Jensen, {Henrik Elvang} and Svalastoga, {Eiliv Lars} and Ulrik Westrup and Fintan McEvoy and Knudsen, {Jes Christian} and Thomsen, {Preben Dybdahl} and Berg, {Lise Charlotte} and Stine Jacobsen and L.H. Christensen",

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AU - Svalastoga, Eiliv Lars

AU - Westrup, Ulrik

AU - McEvoy, Fintan

AU - Knudsen, Jes Christian

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KW - Veterinary medicine

KW - Animal Model

KW - joint disease

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