Changing M3G/M6G ratios and pharmacodynamics in a cancer patient during long-term morphine treatment

Gertrud Andersen; Lona Louring Christrup; Per Sjøgren; Steen Honoré Hansen; Niels-Henrik Jensen

Changing M3G/M6G ratios and pharmacodynamics in a cancer patient during long-term morphine treatment

Gertrud Andersen, Lona Louring Christrup, Per Sjøgren, Steen Honoré Hansen, Niels-Henrik Jensen

11 Citations (Scopus)

Abstract

A cancer patient receiving long-term oral sustained-release morphine treatment and periodically presenting with unusually high plasma M3G/M6G ratios is described. We found the patient's formation of M6G more unstable and perhaps delayed compared to the formation of M3G. There is no apparent explanation for this phenomenon and the high M3G/M6G ratios had no implications for the patient's pain experience or side effects from the morphine treatment.

Original language	English
Journal	Journal of Pain and Symptom Management
Volume	23
Issue number	2
Pages (from-to)	161-4
Number of pages	4
ISSN	0885-3924
Publication status	Published - Feb 2002

Keywords

Analgesics, Opioid
Central Nervous System Stimulants
Humans
Male
Middle Aged
Morphine
Morphine Derivatives
Pain
Prostatic Neoplasms
Time Factors

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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http://www.sciencedirect.com/science/article/pii/S0885392401003980

Cite this

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title = "Changing M3G/M6G ratios and pharmacodynamics in a cancer patient during long-term morphine treatment",

abstract = "A cancer patient receiving long-term oral sustained-release morphine treatment and periodically presenting with unusually high plasma M3G/M6G ratios is described. We found the patient's formation of M6G more unstable and perhaps delayed compared to the formation of M3G. There is no apparent explanation for this phenomenon and the high M3G/M6G ratios had no implications for the patient's pain experience or side effects from the morphine treatment.",

keywords = "Analgesics, Opioid, Central Nervous System Stimulants, Humans, Male, Middle Aged, Morphine, Morphine Derivatives, Pain, Prostatic Neoplasms, Time Factors",

author = "Gertrud Andersen and Christrup, {Lona Louring} and Per Sj{\o}gren and Hansen, {Steen Honor{\'e}} and Niels-Henrik Jensen",

year = "2002",

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language = "English",

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pages = "161--4",

journal = "Journal of Pain and Symptom Management",

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TY - JOUR

T1 - Changing M3G/M6G ratios and pharmacodynamics in a cancer patient during long-term morphine treatment

AU - Andersen, Gertrud

AU - Christrup, Lona Louring

AU - Sjøgren, Per

AU - Hansen, Steen Honoré

AU - Jensen, Niels-Henrik

PY - 2002/2

Y1 - 2002/2

N2 - A cancer patient receiving long-term oral sustained-release morphine treatment and periodically presenting with unusually high plasma M3G/M6G ratios is described. We found the patient's formation of M6G more unstable and perhaps delayed compared to the formation of M3G. There is no apparent explanation for this phenomenon and the high M3G/M6G ratios had no implications for the patient's pain experience or side effects from the morphine treatment.

AB - A cancer patient receiving long-term oral sustained-release morphine treatment and periodically presenting with unusually high plasma M3G/M6G ratios is described. We found the patient's formation of M6G more unstable and perhaps delayed compared to the formation of M3G. There is no apparent explanation for this phenomenon and the high M3G/M6G ratios had no implications for the patient's pain experience or side effects from the morphine treatment.

KW - Analgesics, Opioid

KW - Central Nervous System Stimulants

KW - Humans

KW - Male

KW - Middle Aged

KW - Morphine

KW - Morphine Derivatives

KW - Pain

KW - Prostatic Neoplasms

KW - Time Factors

M3 - Journal article

C2 - 11844638

SN - 0885-3924

VL - 23

SP - 161

EP - 164

JO - Journal of Pain and Symptom Management

JF - Journal of Pain and Symptom Management

IS - 2

ER -

Changing M3G/M6G ratios and pharmacodynamics in a cancer patient during long-term morphine treatment

Abstract

Keywords

UN SDGs

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