Brief Report: Clusters and Trajectories Across the Autism and/or ADHD Spectrum

S LaBianca; A K Pagsberg; K D Jakobsen; A B Demur; M Bartalan; J LaBianca; T Werge

doi:10.1007/s10803-018-3618-6

Brief Report: Clusters and Trajectories Across the Autism and/or ADHD Spectrum

S LaBianca, A K Pagsberg, K D Jakobsen, A B Demur, M Bartalan, J LaBianca, T Werge

Department of Clinical Medicine

2 Citations (Scopus)

Abstract

Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD) frequently co-occur and show high genetic correlation. With the introduction of DSM-5, there is a new concept of an ASD and/or ADHD spectrum (ASD/ADHD). This study aimed to identify predictors of severity and need of healthcare within this spectrum. 39 families with multiple individuals affected by ASD/ADHD were recruited from a psychiatric clinic. Diagnoses, functional and demographic characteristics were retrieved from journals while hospital admissions were identified in the Danish health register. An estimated fraction of 31% ASD/ADHD patients had never been hospitalized and 35% remained undiagnosed despite hospitalization. Cluster analysis identified trajectories that discriminate age of diagnosis, educational attainment to degree of severity, need of hospitalization and genetic risk.

Original language	English
Journal	Journal of Autism and Developmental Disorders
Volume	48
Issue number	10
Pages (from-to)	3629-3636
Number of pages	8
ISSN	0162-3257
DOIs	https://doi.org/10.1007/s10803-018-3618-6
Publication status	Published - 1 Oct 2018

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title = "Brief Report: Clusters and Trajectories Across the Autism and/or ADHD Spectrum",

abstract = "Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD) frequently co-occur and show high genetic correlation. With the introduction of DSM-5, there is a new concept of an ASD and/or ADHD spectrum (ASD/ADHD). This study aimed to identify predictors of severity and need of healthcare within this spectrum. 39 families with multiple individuals affected by ASD/ADHD were recruited from a psychiatric clinic. Diagnoses, functional and demographic characteristics were retrieved from journals while hospital admissions were identified in the Danish health register. An estimated fraction of 31% ASD/ADHD patients had never been hospitalized and 35% remained undiagnosed despite hospitalization. Cluster analysis identified trajectories that discriminate age of diagnosis, educational attainment to degree of severity, need of hospitalization and genetic risk.",

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T2 - Clusters and Trajectories Across the Autism and/or ADHD Spectrum

AU - LaBianca, S

AU - Pagsberg, A K

AU - Jakobsen, K D

AU - Demur, A B

AU - Bartalan, M

AU - LaBianca, J

AU - Werge, T

PY - 2018/10/1

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N2 - Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD) frequently co-occur and show high genetic correlation. With the introduction of DSM-5, there is a new concept of an ASD and/or ADHD spectrum (ASD/ADHD). This study aimed to identify predictors of severity and need of healthcare within this spectrum. 39 families with multiple individuals affected by ASD/ADHD were recruited from a psychiatric clinic. Diagnoses, functional and demographic characteristics were retrieved from journals while hospital admissions were identified in the Danish health register. An estimated fraction of 31% ASD/ADHD patients had never been hospitalized and 35% remained undiagnosed despite hospitalization. Cluster analysis identified trajectories that discriminate age of diagnosis, educational attainment to degree of severity, need of hospitalization and genetic risk.

AB - Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD) frequently co-occur and show high genetic correlation. With the introduction of DSM-5, there is a new concept of an ASD and/or ADHD spectrum (ASD/ADHD). This study aimed to identify predictors of severity and need of healthcare within this spectrum. 39 families with multiple individuals affected by ASD/ADHD were recruited from a psychiatric clinic. Diagnoses, functional and demographic characteristics were retrieved from journals while hospital admissions were identified in the Danish health register. An estimated fraction of 31% ASD/ADHD patients had never been hospitalized and 35% remained undiagnosed despite hospitalization. Cluster analysis identified trajectories that discriminate age of diagnosis, educational attainment to degree of severity, need of hospitalization and genetic risk.

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Brief Report: Clusters and Trajectories Across the Autism and/or ADHD Spectrum

Abstract

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