Brief Report: Clusters and Trajectories Across the Autism and/or ADHD Spectrum

S LaBianca; A K Pagsberg; K D Jakobsen; A B Demur; M Bartalan; J LaBianca; T Werge

doi:10.1007/s10803-018-3618-6

Brief Report: Clusters and Trajectories Across the Autism and/or ADHD Spectrum

S LaBianca, A K Pagsberg, K D Jakobsen, A B Demur, M Bartalan, J LaBianca, T Werge

Institut for Klinisk Medicin

2 Citationer (Scopus)

Abstract

Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD) frequently co-occur and show high genetic correlation. With the introduction of DSM-5, there is a new concept of an ASD and/or ADHD spectrum (ASD/ADHD). This study aimed to identify predictors of severity and need of healthcare within this spectrum. 39 families with multiple individuals affected by ASD/ADHD were recruited from a psychiatric clinic. Diagnoses, functional and demographic characteristics were retrieved from journals while hospital admissions were identified in the Danish health register. An estimated fraction of 31% ASD/ADHD patients had never been hospitalized and 35% remained undiagnosed despite hospitalization. Cluster analysis identified trajectories that discriminate age of diagnosis, educational attainment to degree of severity, need of hospitalization and genetic risk.

Originalsprog	Engelsk
Tidsskrift	Journal of Autism and Developmental Disorders
Vol/bind	48
Udgave nummer	10
Sider (fra-til)	3629-3636
Antal sider	8
ISSN	0162-3257
DOI	https://doi.org/10.1007/s10803-018-3618-6
Status	Udgivet - 1 okt. 2018

Adgang til dokumentet

10.1007/s10803-018-3618-6

Citationsformater

@article{c299558677224ef8a6223641ecf099b7,

title = "Brief Report: Clusters and Trajectories Across the Autism and/or ADHD Spectrum",

abstract = "Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD) frequently co-occur and show high genetic correlation. With the introduction of DSM-5, there is a new concept of an ASD and/or ADHD spectrum (ASD/ADHD). This study aimed to identify predictors of severity and need of healthcare within this spectrum. 39 families with multiple individuals affected by ASD/ADHD were recruited from a psychiatric clinic. Diagnoses, functional and demographic characteristics were retrieved from journals while hospital admissions were identified in the Danish health register. An estimated fraction of 31% ASD/ADHD patients had never been hospitalized and 35% remained undiagnosed despite hospitalization. Cluster analysis identified trajectories that discriminate age of diagnosis, educational attainment to degree of severity, need of hospitalization and genetic risk.",

author = "S LaBianca and Pagsberg, {A K} and Jakobsen, {K D} and Demur, {A B} and M Bartalan and J LaBianca and T Werge",

year = "2018",

month = oct,

day = "1",

doi = "10.1007/s10803-018-3618-6",

language = "English",

volume = "48",

pages = "3629--3636",

journal = "Journal of Autism and Developmental Disorders",

issn = "0162-3257",

publisher = "Springer",

number = "10",

}

TY - JOUR

T1 - Brief Report

T2 - Clusters and Trajectories Across the Autism and/or ADHD Spectrum

AU - LaBianca, S

AU - Pagsberg, A K

AU - Jakobsen, K D

AU - Demur, A B

AU - Bartalan, M

AU - LaBianca, J

AU - Werge, T

PY - 2018/10/1

Y1 - 2018/10/1

N2 - Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD) frequently co-occur and show high genetic correlation. With the introduction of DSM-5, there is a new concept of an ASD and/or ADHD spectrum (ASD/ADHD). This study aimed to identify predictors of severity and need of healthcare within this spectrum. 39 families with multiple individuals affected by ASD/ADHD were recruited from a psychiatric clinic. Diagnoses, functional and demographic characteristics were retrieved from journals while hospital admissions were identified in the Danish health register. An estimated fraction of 31% ASD/ADHD patients had never been hospitalized and 35% remained undiagnosed despite hospitalization. Cluster analysis identified trajectories that discriminate age of diagnosis, educational attainment to degree of severity, need of hospitalization and genetic risk.

AB - Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD) frequently co-occur and show high genetic correlation. With the introduction of DSM-5, there is a new concept of an ASD and/or ADHD spectrum (ASD/ADHD). This study aimed to identify predictors of severity and need of healthcare within this spectrum. 39 families with multiple individuals affected by ASD/ADHD were recruited from a psychiatric clinic. Diagnoses, functional and demographic characteristics were retrieved from journals while hospital admissions were identified in the Danish health register. An estimated fraction of 31% ASD/ADHD patients had never been hospitalized and 35% remained undiagnosed despite hospitalization. Cluster analysis identified trajectories that discriminate age of diagnosis, educational attainment to degree of severity, need of hospitalization and genetic risk.

U2 - 10.1007/s10803-018-3618-6

DO - 10.1007/s10803-018-3618-6

M3 - Journal article

C2 - 29882106

SN - 0162-3257

VL - 48

SP - 3629

EP - 3636

JO - Journal of Autism and Developmental Disorders

JF - Journal of Autism and Developmental Disorders

IS - 10

ER -

Brief Report: Clusters and Trajectories Across the Autism and/or ADHD Spectrum

Abstract

Adgang til dokumentet

Fingeraftryk

Citationsformater