Assessment of mucoadhesion using small deformation rheology revisited

Stine Harloff-Helleberg; Karina Juul Vissing; Hanne Mørck Nielsen

Assessment of mucoadhesion using small deformation rheology revisited

Stine Harloff-Helleberg, Karina Juul Vissing, Hanne Mørck Nielsen

Abstract

This work revisits the commonly used
approach to assess mucoadhesion in drug delivery by small deformation rheology. The results show that biosimilar mucus serves as a more predictive mucus model system when compared to mucin suspensions. Data is fitted including error propagation, different from previous studies only using calculated averages.

Original language	English
Journal	Nordic Rheology Society Annual Transactions
Volume	25
Pages (from-to)	63
Number of pages	7
ISSN	1601-4057
Publication status	Published - Apr 2017
Event	Annual European Rheology Conference & Nordic Rheology Conference - Copenhagen, Denmark Duration: 3 Apr 2017 → 6 Apr 2017 http://www.aerc2017.dk

Conference

Conference	Annual European Rheology Conference & Nordic Rheology Conference
Country/Territory	Denmark
City	Copenhagen
Period	03/04/2017 → 06/04/2017
Internet address	http://www.aerc2017.dk

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Cite this

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title = "Assessment of mucoadhesion using small deformation rheology revisited",

abstract = "This work revisits the commonly usedapproach to assess mucoadhesion in drug delivery by small deformation rheology. The results show that biosimilar mucus serves as a more predictive mucus model system when compared to mucin suspensions. Data is fitted including error propagation, different from previous studies only using calculated averages.",

author = "Stine Harloff-Helleberg and Vissing, {Karina Juul} and Nielsen, {Hanne M{\o}rck}",

year = "2017",

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journal = "Nordic Rheology Society Annual Transactions",

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AU - Harloff-Helleberg, Stine

AU - Vissing, Karina Juul

AU - Nielsen, Hanne Mørck

PY - 2017/4

Y1 - 2017/4

N2 - This work revisits the commonly usedapproach to assess mucoadhesion in drug delivery by small deformation rheology. The results show that biosimilar mucus serves as a more predictive mucus model system when compared to mucin suspensions. Data is fitted including error propagation, different from previous studies only using calculated averages.

AB - This work revisits the commonly usedapproach to assess mucoadhesion in drug delivery by small deformation rheology. The results show that biosimilar mucus serves as a more predictive mucus model system when compared to mucin suspensions. Data is fitted including error propagation, different from previous studies only using calculated averages.

UR - https://nordicrheologysociety.org/AnnualTransactions/ShowAllTransactions

M3 - Conference article

SN - 1601-4057

VL - 25

SP - 63

JO - Nordic Rheology Society Annual Transactions

JF - Nordic Rheology Society Annual Transactions

T2 - Annual European Rheology Conference & Nordic Rheology Conference

Y2 - 3 April 2017 through 6 April 2017

ER -

Assessment of mucoadhesion using small deformation rheology revisited

Abstract

Conference

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