Assessment of mucoadhesion using small deformation rheology revisited

Stine Harloff-Helleberg; Karina Juul Vissing; Hanne Mørck Nielsen

Assessment of mucoadhesion using small deformation rheology revisited

Stine Harloff-Helleberg, Karina Juul Vissing, Hanne Mørck Nielsen

Abstract

This work revisits the commonly used
approach to assess mucoadhesion in drug delivery by small deformation rheology. The results show that biosimilar mucus serves as a more predictive mucus model system when compared to mucin suspensions. Data is fitted including error propagation, different from previous studies only using calculated averages.

Originalsprog	Engelsk
Tidsskrift	Nordic Rheology Society Annual Transactions
Vol/bind	25
Sider (fra-til)	63
Antal sider	7
ISSN	1601-4057
Status	Udgivet - apr. 2017
Begivenhed	Annual European Rheology Conference & Nordic Rheology Conference - Copenhagen, Danmark Varighed: 3 apr. 2017 → 6 apr. 2017 http://www.aerc2017.dk

Konference

Konference	Annual European Rheology Conference & Nordic Rheology Conference
Land/Område	Danmark
By	Copenhagen
Periode	03/04/2017 → 06/04/2017
Internetadresse	http://www.aerc2017.dk

Adgang til dokumentet

https://nrs.blob.core.windows.net/pdfs/nrspdf-a7656c76-19a8-48d6-90af-406fbdb8933a.pdf

Andre filer og links

https://nordicrheologysociety.org/AnnualTransactions/ShowAllTransactions

Citationsformater

@inproceedings{3952c3ea46d842e1aa2e3de3d411f441,

title = "Assessment of mucoadhesion using small deformation rheology revisited",

abstract = "This work revisits the commonly usedapproach to assess mucoadhesion in drug delivery by small deformation rheology. The results show that biosimilar mucus serves as a more predictive mucus model system when compared to mucin suspensions. Data is fitted including error propagation, different from previous studies only using calculated averages.",

author = "Stine Harloff-Helleberg and Vissing, {Karina Juul} and Nielsen, {Hanne M{\o}rck}",

year = "2017",

month = apr,

language = "English",

volume = "25",

pages = "63",

journal = "Nordic Rheology Society Annual Transactions",

issn = "1601-4057",

publisher = "Nordic Rheology Society; 1997",

note = "Annual European Rheology Conference & Nordic Rheology Conference ; Conference date: 03-04-2017 Through 06-04-2017",

url = "http://www.aerc2017.dk",

}

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AU - Harloff-Helleberg, Stine

AU - Vissing, Karina Juul

AU - Nielsen, Hanne Mørck

PY - 2017/4

Y1 - 2017/4

N2 - This work revisits the commonly usedapproach to assess mucoadhesion in drug delivery by small deformation rheology. The results show that biosimilar mucus serves as a more predictive mucus model system when compared to mucin suspensions. Data is fitted including error propagation, different from previous studies only using calculated averages.

AB - This work revisits the commonly usedapproach to assess mucoadhesion in drug delivery by small deformation rheology. The results show that biosimilar mucus serves as a more predictive mucus model system when compared to mucin suspensions. Data is fitted including error propagation, different from previous studies only using calculated averages.

UR - https://nordicrheologysociety.org/AnnualTransactions/ShowAllTransactions

M3 - Conference article

SN - 1601-4057

VL - 25

SP - 63

JO - Nordic Rheology Society Annual Transactions

JF - Nordic Rheology Society Annual Transactions

T2 - Annual European Rheology Conference & Nordic Rheology Conference

Y2 - 3 April 2017 through 6 April 2017

ER -