Antibiotic tolerance and resistance in biofilms

Oana Ciofu, Tim Tolker-Nielsen*

*Corresponding author for this work
18 Citations (Scopus)

Abstract

One of the most important features of microbial biofilms is their tolerance to antimicrobial agents and components of the host immune system. The difficulty of treating biofilm infections with antibiotics is a major clinical problem. Although antibiotics may decrease the number of bacteria in biofilms, they will not completely eradicate the bacteria in vivo which may have important clinical consequences in form of relapses of the infection.

Original languageEnglish
Title of host publicationBiofilm Infections
Number of pages15
PublisherSpringer New York
Publication date1 Dec 2011
Pages215-229
ISBN (Print)9781441960832
DOIs
Publication statusPublished - 1 Dec 2011

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