Analysis of opioid consumption in clinical trials: a simulation based analysis of power of four approaches

Rasmus Vestergaard Juul; Joakim Nyberg; Mads Kreilgaard; Lona Louring Christrup; Ulrika S. H. Simonsson; Trine Meldgaard Lund

doi:10.1007/s10928-017-9522-4

Analysis of opioid consumption in clinical trials: a simulation based analysis of power of four approaches

Rasmus Vestergaard Juul, Joakim Nyberg, Mads Kreilgaard, Lona Louring Christrup, Ulrika S. H. Simonsson, Trine Meldgaard Lund

4 Citations (Scopus)

Original language	English
Journal	Journal of Pharmacokinetics and Pharmacodynamics
Volume	44
Issue number	4
Pages (from-to)	325-333
Number of pages	8
ISSN	1567-567X
DOIs	https://doi.org/10.1007/s10928-017-9522-4
Publication status	Published - 1 Aug 2017

Keywords

Postoperative pain
Analgesics
Repeated time-to-event modeling
Clinical trial simulation
Monte Carlo Mapped Power

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10.1007/s10928-017-9522-4

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title = "Analysis of opioid consumption in clinical trials: a simulation based analysis of power of four approaches",

keywords = "Postoperative pain, Analgesics, Repeated time-to-event modeling, Clinical trial simulation, Monte Carlo Mapped Power",

author = "Juul, {Rasmus Vestergaard} and Joakim Nyberg and Mads Kreilgaard and Christrup, {Lona Louring} and Simonsson, {Ulrika S. H.} and Lund, {Trine Meldgaard}",

year = "2017",

month = aug,

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doi = "10.1007/s10928-017-9522-4",

language = "English",

volume = "44",

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journal = "Journal of Pharmacokinetics and Pharmacodynamics",

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T1 - Analysis of opioid consumption in clinical trials: a simulation based analysis of power of four approaches

AU - Juul, Rasmus Vestergaard

AU - Nyberg, Joakim

AU - Kreilgaard, Mads

AU - Christrup, Lona Louring

AU - Simonsson, Ulrika S. H.

AU - Lund, Trine Meldgaard

PY - 2017/8/1

Y1 - 2017/8/1

KW - Postoperative pain

KW - Analgesics

KW - Repeated time-to-event modeling

KW - Clinical trial simulation

KW - Monte Carlo Mapped Power

U2 - 10.1007/s10928-017-9522-4

DO - 10.1007/s10928-017-9522-4

M3 - Journal article

C2 - 28389762

SN - 1567-567X

VL - 44

SP - 325

EP - 333

JO - Journal of Pharmacokinetics and Pharmacodynamics

JF - Journal of Pharmacokinetics and Pharmacodynamics

IS - 4

ER -

Analysis of opioid consumption in clinical trials: a simulation based analysis of power of four approaches

Keywords

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