Yoshiki Narimatsu

2019

An Atlas of Human Glycosylation Pathways Enables Display of the Human Glycome by Gene Engineered Cells

Narimatsu, Y., Joshi, H. J., Nason, R., Van Coillie, J., Karlsson, R., Sun, L., Ye, Z., Chen, Y.-H., Schjoldager, K. T., Steentoft, C., Furukawa, S., Bensing, B. A., Sullam, P. M., Thompson, A. J., Paulson, J. C., Büll, C., Adema, G. J., Mandel, U., Hansen, L. & Bennett, E. P. & 4 others, Varki, A., Vakhrushev, S. Y., Yang, Z. & Clausen, H., 25 Jul 2019, In: Molecular Cell. 75, 2, p. 394-407, e1-e5

Research output: Contribution to journal › Journal article › Research › peer-review

50 Citations (Scopus)

A strategy for generating cancer-specific monoclonal antibodies to aberrant O-glycoproteins: identification of a novel dysadherin-Tn antibody

Steentoft, C., Fuhrmann, M., Battisti, F., Van Coillie, J., Madsen, T. D., Campos, D., Halim, A., Vakhrushev, S. Y., Joshi, H., Schreiber, H., Mandel, U. & Narimatsu, Y., 6 Feb 2019, In: Glycobiology. 29, 4, p. 307-319 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Erratum: Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions (Journal of Biological Chemistry (2018) 293 (7408-7422) DOI: 10.1074/jbc.M117.817981)

Wang, S., Mao, Y., Narimatsu, Y., Ye, Z., Tian, W., Goth, C. K., Lira-Navarrete, E., Pedersen, N. B., Benito-Vicente, A., Martin, C., Uribe, K. B., Hurtado-Guerrero, R., Christoffersen, C., Seidah, N. G., Nielsen, R., Christensen, E. I., Hansen, L., Bennett, E. P., Vakhrushev, S. Y. & Schjoldager, K. T. & 1 others, Clausen, H., 24 May 2019, In: Journal of Biological Chemistry. 294, 21, 1 p.

Research output: Contribution to journal › Comment/debate › Research › peer-review

2 Citations (Scopus)

Exploring Regulation of Protein O-Glycosylation in Isogenic Human HEK293 Cells by Differential O-Glycoproteomics

Narimatsu, Y., Joshi, H. J., Schjoldager, K. T., Hintze, J., Halim, A., Steentoft, C., Nason, R., Mandel, U., Bennett, E. P., Clausen, H. & Vakhrushev, S. Y., 2019, In: Molecular and Cellular Proteomics. 18, 7, p. 1396-1409

Research output: Contribution to journal › Journal article › Research › peer-review

16 Citations (Scopus)

Multiple distinct O-Mannosylation pathways in eukaryotes

Larsen, I. S. B., Narimatsu, Y., Clausen, H., Joshi, H. J. & Halim, A., Jun 2019, In: Current Opinion in Structural Biology. 56, p. 171-178 8 p.

Research output: Contribution to journal › Review › peer-review

9 Citations (Scopus)

The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells

Tian, W., Ye, Z., Wang, S., Schulz, M. A., Van Coillie, J., Sun, L., Chen, Y.-H., Narimatsu, Y., Hansen, L., Kristensen, C., Mandel, U., Bennett, E. P., Jabbarzadeh-Tabrizi, S., Schiffmann, R., Shen, J.-S., Vakhrushev, S. Y., Clausen, H. & Yang, Z., 1 Dec 2019, In: Nature Communications. 10, 13 p., 1785.

Research output: Contribution to journal › Journal article › Research › peer-review

21 Citations (Scopus)

10 Downloads (Pure)

2018

A validated gRNA library for CRISPR/Cas9 targeting of the human glycosyltransferase genome

Narimatsu, Y., Joshi, H. J., Zhang, Y., Gomes, C., Chen, Y.-H., Lorenzetti, F., Furukawa, S., Schjoldager, K., Hansen, L., Clausen, H., Bennett, E. P. & Wandall, H. H., 1 May 2018, In: Glycobiology. 28, 5, p. 295–305

Research output: Contribution to journal › Journal article › Research › peer-review

29 Citations (Scopus)

Glycosyltransferase genes that cause monogenic congenital disorders of glycosylation are distinct from glycosyltransferase genes associated with complex diseases

Joshi, H. J., Hansen, L., Narimatsu, Y., Freeze, H. H., Henrissat, B., Bennett, E., Wandall, H. H., Clausen, H. & Schjoldager, K. T., 1 May 2018, In: Glycobiology. 28, 5, p. 284-294

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

Probing the contribution of individual polypeptide GalNAc-transferase isoforms to the O-glycoproteome by inducible expression in isogenic cell lines

Hintze, J., Ye, Z., Narimatsu, Y., Madsen, T. D., Joshi, H. J., Goth, C. K., Linstedt, A., Bachert, C., Mandel, U., Bennett, E. P., Vakhrushev, S. Y. & Schjoldager, K. T., 7 Dec 2018, In: The Journal of Biological Chemistry. 293, 49, p. 19064-19077 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions

Wang, S., Mao, Y., Narimatsu, Y., Ye, Z., Tian, W., Goth, C. K., Lira-Navarrete, E., Pedersen, N. B., Benito-Vicente, A., Martin, C., Uribe, K. B., Hurtado-Guerrero, R., Christoffersen, C., Seidah, N. G., Nielsen, R., Christensen, E. I., Hansen, L., Bennett, E. P., Vakhrushev, S. Y. & Schjoldager, K. T. & 1 others, Clausen, H., 11 May 2018, In: The Journal of Biological Chemistry. 293, 19, p. 7408 –7422

Research output: Contribution to journal › Journal article › Research › peer-review

30 Citations (Scopus)

SnapShot: O-Glycosylation Pathways across Kingdoms

Joshi, H. J., Narimatsu, Y., Schjoldager, K. T., Tytgat, H. L. P., Aebi, M., Clausen, H. & Halim, A., 25 Jan 2018, In: Cell. 172, 3, p. 632–632.e2

Research output: Contribution to journal › Review › peer-review

30 Citations (Scopus)

The GAGOme: a cell-based library of displayed glycosaminoglycans

Chen, Y.-H., Narimatsu, Y., Clausen, T. M., Gomes, C., Karlsson, R., Steentoft, C., Spliid, C. B., Gustavsson, T., Salanti, A., Persson, A., Malmström, A., Willén, D., Ellervik, U., Bennett, E. P., Mao, Y., Clausen, H. & Yang, Z., 1 Nov 2018, In: Nature Methods. 15, 11, p. 881-888

Research output: Contribution to journal › Journal article › Research › peer-review

36 Citations (Scopus)

2017

Discovery of an O-mannosylation pathway selectively serving cadherins and protocadherins

Larsen, I. S. B., Narimatsu, Y., Joshi, H. J., Siukstaite, L., Harrison, O. J., Brasch, J., Goodman, K. M., Hansen, L., Shapiro, L., Honig, B., Vakhrushev, S. Y., Clausen, H. & Halim, A., 17 Oct 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 42, p. 11163-11168 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

35 Citations (Scopus)

Dynamics of Indel Profiles Induced by Various CRISPR/Cas9 Delivery Methods

Kosicki, M., Rajan, S. S., Lorenzetti, F. C., Wandall, H. H., Narimatsu, Y., Metzakopian, E. & Bennett, E. P., 2017, In: Progress in Molecular Biology and Translational Science. 152, p. 49-67 19 p.

Research output: Contribution to journal › Journal article › Research › peer-review

10 Citations (Scopus)

Fine-tuning limited proteolysis - A novel role for regulated site-specific O-glycosylation in beta 1-Adrenergic Receptor cleavage and function

Goth, C. K., Tuhkanen, H. E., Khan, H., Wang, S., Narimatsu, Y., Hansen, L. H., Overall, C., Clausen, H., Schjoldager, K. T. & Petaja-Repo, U., Dec 2017, In: Glycobiology. 27, 12, p. 1204-1204 84.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Genome editing using FACS enrichment of nuclease-expressing cells and indel detection by amplicon analysis

Lonowski, L. A., Narimatsu, Y., Riaz, A., Delay, C. M. E., Yang, Z., Niola, F., Duda, K., Ober, E. A., Clausen, H., Wandall, H. H., Hansen, S. H., Bennett, E. P. & Frödin, M., 1 Mar 2017, In: Nature Protocols. 12, 3, p. 581-603 23 p.

Research output: Contribution to journal › Journal article › Research › peer-review

54 Citations (Scopus)

Mammalian O-mannosylation of Cadherins and Plexins is Independent of Protein O-mannosyltransferase 1 and 2

Larsen, I. S. B., Narimatsu, Y., Joshi, H. J., Yang, Z., Harrison, O. J., Brasch, J., Shapiro, L., Honig, B., Vakhrushev, S. Y., Clausen, H. & Halim, A., 7 Jul 2017, In: The Journal of Biological Chemistry. 292, p. 11586-11598

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

Revisiting the human polypeptide GalNAc-T1 and T13 paralogs

Festari, M. F., Trajtenberg, F., Berois, N., Pantano, S., Revoredo, L., Kong, Y., Solari-Saquieres, P., Narimatsu, Y., Freire, T., Bay, S., Robello, C., Bénard, J., Gerken, T. A., Clausen, H. & Osinaga, E., Jan 2017, In: Glycobiology. 27, 2, p. 140-153 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Site-specific O-Glycosylation by Polypeptide N-Acetylgalactosaminyltransferase 2 (GalNAc-transferase T2) Co-regulates β1-Adrenergic Receptor N-terminal Cleavage

Goth, C. K., Tuhkanen, H. E., Khan, H., Lackman, J. J., Wang, S., Narimatsu, Y., Hansen, L. H., Overall, C. M., Clausen, H., Schjoldager, K. T. & Petäjä-Repo, U. E., 17 Mar 2017, In: The Journal of Biological Chemistry. 292, 11, p. 4714-4726 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

2014

Advances in mass spectrometry driven O-glycoproteomics

Levery, S. B., Steentoft, C., Halim, A., Narimatsu, Y., Clausen, H. & Vakhrushev, S. Y., 2014, In: B B A - Reviews on Cancer. 1850, 1, p. 33-42 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

78 Citations (Scopus)

Characterization of Binding Epitopes of CA125 Monoclonal Antibodies

da Silva, L. P. M., Narimatsu, Y., Halim, A., Vieira Campos, D. A., Yang, Z., Tarp, M. P. A., Pereira, P. J. B., Mandel, U., Bennett, E. P., Vakhrushev, S. Y., Levery, S. B., David, L. & Clausen, H., 3 Jul 2014, In: Journal of Proteome Research. 13, 7, p. 3349-59 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

25 Citations (Scopus)

Low Density Lipoprotein Receptor Class A Repeats Are O-Glycosylated in Linker Regions

Pedersen, N. B., Wang, S., Narimatsu, Y., Yang, Z., Halim, A., Schjoldager, K.T.-B. G., Madsen, T. D., Seidah, N. G., Bennett, E. P., Levery, S. B. & Clausen, H., 20 Jun 2014, In: The Journal of Biological Chemistry. 289, 25, p. 17312-17324 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

29 Citations (Scopus)

The GalNAc-type O-glycoproteome of CHO cells characterized by the SimpleCell strategy

Yang, Z., Halim, A., Narimatsu, Y., Joshi, H. J., Steentoft, C., Schjoldager, K.T.-B. G., Schulz, M. A., Sealover, N. R., Kayser, K. J., Bennett, E. P., Levery, S. B., Vakhrushev, S. Y. & Clausen, H., 1 Dec 2014, In: Molecular & Cellular Proteomics. 13, 12, p. 3224-3235 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

53 Citations (Scopus)

Yoshiki Narimatsu

Research output

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