Thomas Jespersen

Research output

Research output per year 1997 2004 2009 2011 2015 2017 2018 2019 2021

• 114 Journal article
• 2 Article in proceedings
• 2 Review
• 1 Ph.D. thesis
• 5 More
  • 1 Book chapter
  • 1 Conference abstract for conference
  • 1 Poster
  • 1 Conference abstract in journal
  • 1 Letter

Research output per year

Research output per year

Search results

• 2004

  5-HT1A receptors modulate small-conductance Ca2+-activated K+ channels.

  Grunnet, M., Jespersen, T. & Perrier, J-F., 2004, In: Journal of Neuroscience Research. 78, 6, p. 845-54 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • 8-Hydroxy-2-(di-n-propylamino)tetralin 100%
  • Calcium-Activated Potassium Channels 98%
  • Receptor, Serotonin, 5-HT1A 93%
  • hydroxide ion 85%
  • Action Potentials 67%
  33 Citations (Scopus)

• An RNA secondary structure bias for non-homologous reverse transcriptase-mediated deletions in vivo

  Duch, M. R., Carrasco, M. L., Jespersen, T., Aagaard, L., Pedersen, F. S. & Jespersen, T., 1 Jan 2004, In: Nucleic Acids Symposium Series. 32, 6, p. 2039-48 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • RNA-Directed DNA Polymerase 100%
  • Genetic Recombination 82%
  • Internal Ribosome Entry Sites 73%
  • RNA 59%
  • Murine Leukemia Viruses 22%
  12 Citations (Scopus)

• Basolateral localisation of KCNQ1 potassium channels in MDCK cells: molecular identification of an N-terminal targeting motif.

  Jespersen, T., Rasmussen, H. B., Grunnet, M., Jensen, H. S., Angelo, K., Dupuis, D. S., Vogel, L. K., Jorgensen, N. K., Klaerke, D. A. & Olesen, S-P., 2004, In: Journal of Cell Science. 117, Pt 19, p. 4517-26 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • KCNQ1 Potassium Channel 100%
  • Madin Darby Canine Kidney Cells 69%
  • Tyrosine 51%
  • Leucine 38%
  • Epithelium 28%
  43 Citations (Scopus)

• Difference in allelic expression of the CLCN1 gene and the possible influence on the myotonia congenita phenotype.

  Dunø, M., Colding-Jørgensen, E., Grunnet, M., Jespersen, T., Vissing, J. & Schwartz, M., 2004, In: European Journal of Human Genetics. 12, 9, p. 738-43 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Myotonia Congenita 100%
  • Myotonia 50%
  • Phenotype 41%
  • Gene Expression 40%
  • Mutation 28%
  60 Citations (Scopus)

• Does KCNE5 play a role in long QT syndrome?

  Hofman-Bang, J., Jespersen, T., Grunnet, M., Larsen, L. A., Andersen, P. S., Kanters, J. K., Kjeldsen, K. & Christiansen, M., 2004, In: Clinica Chimica Acta. 345, 1-2, p. 49-53 4 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Long QT Syndrome 100%
  • Mutation 64%
  • Ion Channels 28%
  • DNA Sequencing 19%
  • Ion 18%
  10 Citations (Scopus)

• Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins.

  Rougier, J-S., van Bemmelen, M. X., Bruce, M. C., Jespersen, T., Gavillet, B., Apothéloz, F., Cordonier, S., Staub, O., Rotin, D. & Abriel, H., 2004, In: American Journal of Physiology: Cell Physiology. 288, 3, p. C692-701

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Nedd4 Ubiquitin Protein Ligases 100%
  • WW Domains 84%
  • Voltage-Gated Sodium Channels 73%
  • HEK293 Cells 39%
  • Down-Regulation 38%
  103 Citations (Scopus)

• Recruitment of motor neuronal persistent inward currents shapes withdrawal reflexes in the frog

  Grunnet, M., Jespersen, T. & Perrier, J-F. M., 2004, In: Journal of Neuroscience Research. 78, p. 845-854

  Research output: Contribution to journal › Journal article › Research › peer-review

• Transgene stability for three replication-competent murine leukemia virus vectors

  Duch, M. R., Carrasco, M. L., Jespersen, T., Hansen, B. D., Pedersen, F. S. & Jespersen, T., 31 Mar 2004, In: Gene. 329, p. 61-9 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Internal Ribosome Entry Sites 100%
  • Murine Leukemia Viruses 91%
  • enhanced green fluorescent protein 86%
  • Nucleic Acid Repetitive Sequences 84%
  • Viral Genome 79%
  8 Citations (Scopus)
• 2003

  Characterization of two new dominant ClC-1 channel mutations associated with myotonia.

  Grunnet, M., Jespersen, T., Colding-Jørgensen, E., Schwartz, M., Klaerke, D. A., Vissing, J., Olesen, S-P. & Dunø, M., 2003, In: Muscle & Nerve. 28, 6, p. 722-32 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Myotonia 100%
  • Myotonia Congenita 99%
  • Membrane Potentials 44%
  • Mutation 38%
  • Chloride Channels 28%
  18 Citations (Scopus)

• KCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels.

  Grunnet, M., Rasmussen, H. B., Hay-Schmidt, A., Rosenstierne, M., Klaerke, D. A., Olesen, S-P. & Jespersen, T., 2003, In: Biophysical Journal. 85, 3, p. 1525-37 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Kv1.1 Potassium Channel 100%
  • Kv1.3 Potassium Channel 98%
  • Shaker Superfamily of Potassium Channels 46%
  • Messenger RNA 30%
  • HEK293 Cells 29%
  51 Citations (Scopus)

• KCNQ1 channels sense small changes in cell volume.

  Grunnet, M., Jespersen, T., MacAulay, N., Jørgensen, N. K., Schmitt, N., Pongs, O., Olesen, S-P. & Klærke, D. A., 2003, In: Journal of Physiology. 549, Pt 2, p. 419-27 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  76 Citations (Scopus)

• Mutational library analysis of selected amino acids in the receptor binding domain of envelope of Akv murine leukemia virus by conditionally replication competent bicistronic vectors

  Bahrami, S., Jespersen, T., Pedersen, F. S., Duch, M. R. & Jespersen, T., 2 Oct 2003, In: Gene. 315, p. 51-61 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Amino Acid Receptors 100%
  • Internal Ribosome Entry Sites 93%
  • Murine Leukemia Viruses 85%
  • Virus Replication 65%
  • Libraries 57%
  10 Citations (Scopus)

• Solid-phase synthesis and biological activity of a thioether analogue of conotoxin G1.

  Bondebjerg, J., Grunnet, M., Jespersen, T. & Meldal, M., 2003, In: ChemBioChem. 4, 2-3, p. 186-94 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Solid-Phase Synthesis Techniques 100%
  • Conotoxins 98%
  • Sulfides 83%
  • Bioactivity 44%
  • 9-fluorenylmethoxycarbonyl 42%
  41 Citations (Scopus)
• 2002

  Activation of KCNQ5 channels stably expressed in HEK293 cells by BMS-204352.

  Dupuis, D. S., Schrøder, R. L., Jespersen, T., Christensen, J. K., Christophersen, P., Jensen, B. S. & Olesen, S-P., 2002, In: European Journal of Pharmacology. 437, 3, p. 129-37 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • BMS204352 100%
  • HEK293 Cells 52%
  • ezogabine 34%
  • linopirdine 25%
  • 1-phenylindolin-2-one 15%
  65 Citations (Scopus)

• Dual-function vector for protein expression in both mammalian cells and Xenopus laevis oocytes

  Jespersen, T., Grunnet, M., Angelo, K., Klaerke, D. A. & Olesen, S. P., 1 Mar 2002, In: BioTechniques. 32, 3, p. 536-8, 540

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Xenopus laevis 100%
  • Mammalian Cell 88%
  • Oocytes 79%
  • Protein 35%
  • Proteins 31%
  119 Citations (Scopus)

• KCNE4 is an inhibitory subunit to the KCNQ1 channel.

  Grunnet, M., Jespersen, T., Rasmussen, H. B., Ljungstrøm, T., Jorgensen, N. K., Olesen, S-P. & Klaerke, D. A., 2002, In: Journal of Physiology. 542, Pt 1, p. 119-30 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Oocytes 100%
  • Cell Membrane 77%
  • CHO Cells 63%
  • Potassium Channels 61%
  • Xenopus 56%
  123 Citations (Scopus)

• KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current.

  Angelo, K., Jespersen, T., Grunnet, M., Nielsen, M. S., Klaerke, D. A. & Olesen, S-P., 2002, In: Biophysical Journal. 83, 4, p. 1997-2006 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Ether 100%
  • Protein Domains 90%
  • Direction compound 64%
  • Temperature 64%
  • Heart 58%
  87 Citations (Scopus)
• 2001

  An ERG channel inhibitor from the scorpion Buthus eupeus

  Korolkova, Y. V., Kozlov, S. A., Lipkin, A. V., Pluzhnikov, K. A., Hadley, J. K., Filippov, A. K., Brown, D. A., Pedersen, K. A., Strøbaek, D., Jespersen, T., Olesen, S-P., Jensen Skanning, B. & Grishin, E. V., 30 Mar 2001, In: Journal of Biological Chemistry. 276, 13, p. 9868-76 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Scorpions 100%
  • Complementary DNA 73%
  • Potassium Channel Blockers 69%
  • Toxin 66%
  • Amino-Acid Residue 41%
  83 Citations (Scopus)

• KCNQ4 channel activation by BMS-204352 and retigabine

  Schrøder, R. L. K., Jespersen, T., Christophersen, P., Strøbaek, D., Jensen, B. S. & Olesen, S. P., 1 Jun 2001, In: Neuropharmacology. 40, 7, p. 888-98 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • BMS204352 100%
  • ezogabine 80%
  • Potassium Channels 33%
  • linopirdine 17%
  • Epilepsy 16%
  112 Citations (Scopus)

• Pharmacological modulation of SK3 channels

  Grunnet, M., Jespersen, T., Angelo, K., Frøkjaer-Jensen, C., Klaerke, D. A., Olesen, S. P. & Jensen, B. S., 1 Jun 2001, In: Neuropharmacology. 40, 7, p. 879-887 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Calcium-Activated Potassium Channels 100%
  • 4-Aminopyridine 65%
  • Bicuculline 62%
  • Pharmacology 50%
  • Inhibitory Concentration 50 46%
  105 Citations (Scopus)
• 1999

  Analysis and exploitation of murine leukemia virus cis- and trans-elements using novel transduction systems

  Jespersen, T., 3 Mar 1999

  Research output: Book/Report › Ph.D. thesis

• Expression of heterologous genes from an IRES translational cassette in replication competent murine leukemia virus vectors

  Jespersen, T., Duch, M. R., Carrasco, M. L., Warming, S. & Pedersen, F. S., 1 Nov 1999, In: Gene. 239, 2, p. 227-35 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Internal Ribosome Entry Sites 100%
  • Murine Leukemia Viruses 91%
  • Fluorescence 42%
  • Gene Expression 41%
  • Encephalomyocarditis virus 25%
  28 Citations (Scopus)

• Functional testing of a bicistronic retroviral vector for intracellular peptide production

  Duch, M. R., Tolstrup, A., Dalum, I., Jespersen, T., Mouritsen, S. & Pedersen, F. S., 1 Jun 1999, In: BioTechniques. 26, 6, p. 1032-4, 1036

  Research output: Contribution to journal › Journal article › Research › peer-review

  5 Citations (Scopus)
• 1997

  Efficient non-PCR-mediated overlap extension of PCR fragments by exonuclease "end polishing"

  Jespersen, T., Duch, M. R. & Pedersen, F. S., 1 Jul 1997, In: BioTechniques. 23, 1, p. 48, 50, 52

  Research output: Contribution to journal › Journal article › Research › peer-review

  6 Citations (Scopus)