Saskia Hoffmann

2019

Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability

Achuthankutty, D., Thakur, R. S., Haahr, P., Hoffmann, S., Drainas, A. P., Bizard, A. H., Weischenfeldt, J., Hickson, I. D. & Mailand, N., 2 Dec 2019, In: The Journal of Cell Biology. 218, 12, 11 p., 3943.

Research output: Contribution to journal › Journal article › Research › peer-review

TRAIP drives replisome disassembly and mitotic DNA repair synthesis at sites of incomplete DNA replication

Sonneville, R., Bhowmick, R., Hoffmann, S., Mailand, N., Hickson, I. D. & Labib, K., Sept 2019, In: eLife. 8, 19 p., e48686.

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

12 Downloads (Pure)

2018

ZUFSP Deubiquitylates K63-Linked Polyubiquitin Chains to Promote Genome Stability

Haahr, P., Borgermann, N., Guo, X., Typas, D., Achuthankutty, D., Hoffmann, S., Shearer, R., Sixma, T. K. & Mailand, N., 5 Apr 2018, In: Molecular Cell. 70, 1, p. 165-174

Research output: Contribution to journal › Journal article › Research › peer-review

40 Citations (Scopus)

79 Downloads (Pure)

2017

RADX interacts with single-stranded DNA to promote replication fork stability

Schubert, L., Ho, T., Hoffmann, S., Haahr, P., Guérillon, C. & Mailand, N., Nov 2017, In: EMBO Reports. 18, 11, p. 1991-2003 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

41 Downloads (Pure)

2016

Activation of the ATR kinase by the RPA-binding protein ETAA1

Haahr, P., Hoffmann, S., Tollenaere, M. A. X., Ho, T., Toledo Lazaro, L. I., Mann, M., Bekker-Jensen, S., Räschle, M. & Mailand, N., 27 Oct 2016, In: Nature Cell Biology. 18, 11, p. 1196–1207

Research output: Contribution to journal › Journal article › Research › peer-review

106 Citations (Scopus)

1235 Downloads (Pure)

SCF^{Cyclin F}-dependent degradation of CDC6 suppresses DNA re-replication

Walter, D., Hoffmann, S., Komseli, E-S., Rappsilber, J., Gorgoulis, V. & Sørensen, C. S., 28 Jan 2016, In: Nature Communications. 7, 10 p., 10530.

Research output: Contribution to journal › Journal article › Research › peer-review

48 Citations (Scopus)

TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress

Hoffmann, S., Smedegaard, S., Nakamura, K., Mortuza, G. B., Räschle, M., Ibañez de Opakua, A., Oka, Y., Feng, Y., Blanco, F. J., Mann, M., Montoya, G., Groth, A., Bekker-Jensen, S. & Mailand, N., 1 Jan 2016, In: The Journal of Cell Biology. 212, 1, p. 63-75

Research output: Contribution to journal › Journal article › Research › peer-review

41 Citations (Scopus)

591 Downloads (Pure)

2015

Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control

Klein, D. K., Hoffmann, S., Ahlskog, J. K., O'Hanlon, K., Quaas, M., Larsen, B. D., Rolland, B., Rösner, H. I., Walter, D., Kousholt, A. N., Menzel, T., Lees, M., Johansen, J. V., Rappsilber, J., Engeland, K. & Sørensen, C. S., 5 Jan 2015, In: Nature Communications. 6, p. 5800

Research output: Contribution to journal › Journal article › Research › peer-review

38 Citations (Scopus)

Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage

Thorslund, T., Ripplinger, A., Hoffmann, S., Wild, T., Uckelmann, M., Villumsen, B., Narita, T., Sixma, T. K., Choudhary, C. R., Bekker-Jensen, S. & Mailand, N., 19 Nov 2015, In: Nature. 527, 7578, p. 389-93 5 p.

Research output: Contribution to journal › Letter › peer-review

199 Citations (Scopus)

261 Downloads (Pure)

Saskia Hoffmann

Research output

Search results