Research output per year
Research output per year
Research output
Search results
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2019
Azotides as Modular Peptide-Based Ligands for Asymmetric Lewis Acid Catalysis
Jacobsen, C. B., Nielsen, D. S., Meldal, M. & Diness, F., 7 Jun 2019, In: Journal of Organic Chemistry. 84, 11, p. 6940-6945 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Computational Evolution of Threonine-Rich β-Hairpin Peptides Mimicking Specificity and Affinity of Antibodies
Hu, H., Kofoed, C., Li, M., Gonçalves, J. P. L., Hansen, J., Wolfram, M., Hansen, A. K., Friis Hansen, C. H., Diness, F., Schoffelen, S. & Meldal, M., 27 Feb 2019, In: ACS Central Science. 5, 2, p. 259-269 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Semisynthesis of an Active Enzyme by Quantitative Click Ligation
Kofoed, C., Riesenberg, S., Šmolíková, J., Meldal, M. & Schoffelen, S., 17 Apr 2019, In: Bioconjugate Chemistry. 30, 4, p. 1169-1174Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis of Shld Derivatives, Their Binding to the Destabilizing Domain, and Influence on Protein Accumulation in Transgenic Plants
Jørgensen, F. P., Madsen, D., Meldal, M., Olsen, J. V., Petersen, M., Granhøj, J. & Bols, M., 23 May 2019, In: Journal of Medicinal Chemistry. 62, 10, p. 5191-5216 26 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2018
MC4R Agonists: Structural Overview on Antiobesity Therapeutics
Gonçalves, J., Palmer, D. & Meldal, M. P., Apr 2018, In: Trends in Pharmacological Sciences. 39, 4, p. 402-423 22 p.Research output: Contribution to journal › Review › peer-review
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Metallo-Organozymes with Specific Proteolytic Activity
Embaby, A. M., Lelieveldt, L. P. W. M., Diness, F. & Meldal, M., 27 Nov 2018, In: Chemistry - A European Journal. 24, 66, p. 17424-17428 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rational Tuning of Fluorobenzene Probes for Cysteine-Selective Protein Modification
Embaby, A. M., Schoffelen, S., Kofoed, C., Meldal, M. P. & Diness, F., 2 Jul 2018, In: Angewandte Chemie International Edition. 57, 27, p. 8022-8026 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Screening for selective aggrecanase substrates to detect early proteolytic events in cartilage degradation
Fowkes, M. M., Meldal, M. P., Vincent, T. L. & Lim, N. H., 2018, p. S471. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
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Sustainable Flow Synthesis of Encoded Beads for Combinatorial Chemistry and Chemical Biology
Hu, H., Nikitin, S., Berthelsen, A. B., Diness, F., Schoffelen, S. & Meldal, M. P., 13 Aug 2018, In: ACS Combinatorial Science. 20, 8, p. 492-498 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2017
Advances in merging triazoles with peptides and proteins
Diness, F., Schoffelen, S. & Meldal, M. P., 2017, [Awaiting title]. Springer, p. 1-38 38 p. (Topics in Heterocyclic Chemistry).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Click-Chemistry-Mediated Synthesis of Selective Melanocortin Receptor 4 Agonists
Palmer, D., Gonçalves, J. P. L., Hansen, L. V., Wu, B., Hald, H., Schoffelen, S., Diness, F., Le Quement, S. T., Nielsen, T. E. & Meldal, M., 2017, In: Journal of Medicinal Chemistry. 60, 21, p. 8716-8730 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Diversity-Oriented Syntheses by Combining CuAAC and Stereoselective INCIC Reactions with Peptides
Wang, Y., Madsen, A., Diness, F. & Meldal, M., 9 Oct 2017, In: Chemistry - A European Journal. 23, 56, p. 13869–13874 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mechanism and Scope of Base-Controlled Catalyst-Free N-Arylation of Amines with Unactivated Fluorobenzenes
Jacobsen, C. B., Meldal, M. P. & Diness, F., 18 Jan 2017, In: Chemistry: A European Journal. 23, 4, p. 846-851 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2016
Click chemistry mediated functionalization of vertical nanowires for biological applications
Vutti, S., Schoffelen, S., Bolinsson, J., Buch-Månson, N., Bovet, N. E., Nygård, J., Martinez, K. L. & Meldal, M. P., 2016, In: Chemistry: A European Journal. 22, 2, p. 496-500 5 p.Research output: Contribution to journal › Letter › peer-review
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Click-chemistry of polymersomes on nanoporous polymeric surfaces
Rein, C., Nissen, S., Grzelakowski, M. & Meldal, M. P., 1 Jul 2016, In: Journal of Polymer Science. Part A, Polymer Chemistry. 54, 13, p. 2032-2039 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparative studies of adhesion peptides based on L- or D-amino acids
Nikitin, S., Palmer, D., Meldal, M. P. & Diness, F., 1 Oct 2016, In: Journal of Peptide Science. 22, 10, p. 642-646 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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C-Terminally modified peptides via cleavage of the HMBA linker by O-, N- or S-nucleophiles
Hansen, J., Diness, F. & Meldal, M. P., 2016, In: Organic & Biomolecular Chemistry. 14, 12, p. 3238-3245 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Heterologous expression of peptidyl-Lys metallopeptidase of Armillaria mellea and mutagenic analysis of the recombinant peptidase
Ødum, A. S. R., Østergaard, S., Nørby, I., Meldal, M. P. & Olesen, K., 1 Apr 2016, In: Journal of Biochemistry. 159, 4, p. 461-470 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Novel application of peptidyl-lys metallopeptidase as a C-terminal processing protease
Ødum, A. S. R., Østergaard, S., Nørby, I., Meldal, M. P. & Olesen, K., 1 Feb 2016, In: Protein and Peptide Letters. 23, 4, p. 396-403 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Recent advances in covalent, site-specific protein immobilization [version 1; referees: 3 approved]
Meldal, M. P. & Schoffelen, S., 2016, In: F1000Research. 5, 11 p., 2303.Research output: Contribution to journal › Review › peer-review
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Specific electrostatic molecular recognition in water
Li, M., Hoeck, C., Schoffelen, S., Gotfredsen, C. H. & Meldal, M. P., 17 May 2016, In: Chemistry: A European Journal. 22, 21, p. 7206-7214 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2015
Alkyne-azide reactions
Schoffelen, S. & Meldal, M. P., 9 Feb 2015, Modern alkyne chemistry: catalytic and atom-economic transformations. Trost, B. M. & Li, C-J. (eds.). Wiley-VCH, p. 115-142 28 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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A single-vector EYFP reporter gene assay for G protein-coupled receptors
Hald, H., Wu, B., Bouakaz, L. & Meldal, M. P., 1 May 2015, In: Analytical Biochemistry. 476, p. 40-44 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Covalent and stable CuAAC modification of silicon surfaces for control of cell adhesion
Vutti, S., Buch-Månson, N., Schoffelen, S., Bovet, N. E., Martinez, K. L. & Meldal, M. P., 23 Mar 2015, In: ChemBioChem. 16, 5, p. 782-791 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fmox: a base-labile aldehyde protecting group
Diness, F. & Meldal, M. P., Mar 2015, In: European Journal of Organic Chemistry. 2015, 7, p. 1433-1436 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Substrate specificity profiling of Peptidyl-Lys metallopeptidase of Armillaria mellea by FRET based peptide library
Ødum, A. S. R., Olesen, K., Østergaard, S., Thim, L., Nørby, I. & Meldal, M. P., 2015, In: Protein and Peptide Letters. 22, 6, p. 514-524 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
3 Citations (Scopus) -
2014
In vivo imaging of matrix metalloprotease 12 and matrix metalloprotease 13 activities in the mouse model of collagen-induced arthritis
Lim, N. H., Meinjohanns, E., Bou-Gharios, G., Gompels, L. L., Nuti, E., Rossello, A., Devel, L., Dive, V., Meldal, M. P. & Nagase, H., Mar 2014, In: Arthritis & Rheumatism. 66, 3, p. 589-598 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vivo imaging of MMP-13 activity in the murine destabilised medial meniscus surgical model of osteoarthritis
Lim, N. H., Meinjohanns, E., Meldal, M. P., Bou-Gharios, G. & Nagase, H., Jun 2014, In: Osteoarthritis and Cartilage. 22, 6, p. 862-868 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2012
D-amino acid adhesion peptides by combinatorial selection: control of cellular growth on inert surfaces
Meldal, M. P., Wu, B., Diness, F., Michael, R., Hagel, G., Nygaard, J. & Martinez, K., 2012, In: Journal of Peptide Science. 18, S1, p. S21-S22 2 p., IL1.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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2011
A comparative study of the physicochemical properties of iron isomaltoside 1000 (Monofer®), a new intravenous iron preparation and its clinical implications
Jahn, M. R., Andreasen, H. B., Fütterer, S., Nawroth, T., Schünemann, V., Kolb, U., Hofmeister, W., Muños, M., Bock, K., Meldal, M. P. & Langguth, P., Aug 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 78, p. 480–491Research output: Contribution to journal › Journal article › Research › peer-review
166 Citations (Scopus) -
Identifying a compound modifying a cellular response, comprises attaching cells having a reporter system onto solid supports, releasing a library member, screening and identifying target cells
Hagel, G., Thastrup, O., Meldal, M. P., Norrild, J. C., Hentzer, M., Norrild, J. & Diness, F., 29 Dec 2011, IPC No. G01N 35/ 00 A N, Patent No. US2011319274, Priority date 25 May 2005, Priority No. WO2005DK00348Research output: Patent
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Lectin Domains of Polypeptide GalNAc Transferases Exhibit Glycopeptide Binding Specificity
Pedersen, J. W., Bennett, E. P., Schjoldager, K. T-B. G., Meldal, M., Holmér, A. P., Blixt, O., Cló, E., Levery, S. B., Clausen, H. & Wandall, H. H., 16 Sept 2011, In: The Journal of Biological Chemistry. 286, 37, p. 32684-96 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Maintaining Biological Activity by Using Triazoles as Disufide Bond Mimetics
Holland-Nell, K. & Meldal, M. P., 23 May 2011, In: Angewandte Chemie - German Edition. 123, p. 5310–5312Research output: Contribution to journal › Journal article › Research › peer-review
83 Citations (Scopus) -
Metabolically stable cellular adhesion to inert surfaces
Meldal, M. P., Wu, B., Diness, F., Michael, R. & Hagel, G., 4 Nov 2011, In: ChemBioChem. 12, p. 2463–2470Research output: Contribution to journal › Journal article › Research › peer-review
4 Citations (Scopus) -
Methods for the preparation of chlorophyllide a: An intermediate of the chlorophyll biosynthetic pathway
Muller, A. H., Gough, S. P., Bollivar, D. W., Meldal, M. P., Willows, R. D. & Hansson, M., 15 Dec 2011, In: Analytical Biochemistry. 419, p. 271-276Research output: Contribution to journal › Journal article › Research › peer-review
14 Citations (Scopus) -
Simultaneous "One Pot" Expressed Protein Ligation and Cu-I-Catalyzed Azide/Alkyne Cycloaddition for Protein Immobilization
Steinhagen, M., Holland-Nell, K., Meldal, M. P. & Beck-Sickinger, A. G., 4 Nov 2011, In: ChemBioChem. 12, p. 2426-2430Research output: Contribution to journal › Journal article › Research › peer-review
15 Citations (Scopus) -
2010
Amino acid derived 1,4-dialkyl substituted imidazolones
Diness, F. & Meldal, M. P., 11 Mar 2010, In: Biopolymers. 94, 2, p. 236-241Research output: Contribution to journal › Journal article › Research › peer-review
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Ralph F. Hirschmann award address 2009: merger of organic chemistry with peptide diversity
Meldal, M., Tornøe, C. W., Nielsen, T. E., Diness, F., Le Quement, S. T., Christensen, C. A., Jensen, J. F., Worm-Leonhard, K., Groth, T., Bouakaz, L., Wu, B., Hagel, G. & Keinicke, L., 2010, In: Biopolymers. 94, 2, p. 161-182 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2009
Imidazolones in diastereoselective cyclization reactions and Cu(II)-catalysed cross-coupling reactions
Diness, F. & Meldal, M., 20 Jul 2009, In: Chemistry: A European Journal. 15, 29, p. 7044-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2006
Solid-phase synthesis of tetrahydro-beta-carbolines and tetrahydroisoquinolines by stereoselective intramolecular N-carbamyliminium Pictet-Spengler reactions
Diness, F. & Meldal, M., 25 Oct 2006, In: Chemistry: A European Journal. 12, 31, p. 8056-66 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2005
Dual approach to intramolecular carbamoyliminium activated solid phase Pictet-Spengler reactions
Diness, F. & Meldal, M., 2005, Peptides 2004, Proceedings. p. 208-209Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Reversible Dimerization of Acid-Denatured ACBP Controlled by Helix A4
Fieber, W., Kragelund, B. B., Meldal, M. P. & Poulsen, F. M., 2005, In: Biochemistry. 44, 5, p. 1375-1384Research output: Contribution to journal › Journal article › Research › peer-review
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2004
INTRAMOLECULAR CARBAMOYLIMINIUM ACTIVATED SOLID PHASE PICTET-SPENGLER REACTIONS. TOWARDS MCR AGONISTS
Diness, F., Beyer, J. & Meldal, M., 2004, In: Journal of Peptide Science. 10, p. 126-126Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis of 3-Boc-(1,3)-oxazinane-protected amino aldehydes from amino acids and their conversion into urea precursors. Novel building blocks for combinatorial synthesis
Diness, F., Beyer, J. & Meldal, M., Apr 2004, In: Molecular Informatics. 23, 2-3, p. 130-144Research output: Contribution to journal › Journal article › Research › peer-review
17 Citations (Scopus) -
2003
Solid-phase synthesis and biological activity of a thioether analogue of conotoxin G1.
Bondebjerg, J., Grunnet, M., Jespersen, T. & Meldal, M., 2003, In: ChemBioChem. 4, 2-3, p. 186-94 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Pictet-Spengler reaction in solid-phase combinatorial chemistry
Nielsen, T. E., Diness, F. & Meldal, M., Nov 2003, In: Current Opinion in Drug Discovery & Development. 6, 6, p. 801-14 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
66 Citations (Scopus) -
1998
Kinetic analysis of the mechanism and specificity of protein-disulfide isomerase using fluorescence-quenched peptides
Westphal, V., Spetzler, J. C., Meldal, M., Christensen, U. & Winther, J. R., 1998, In: Journal of Biological Chemistry. 273, 39, p. 24992-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
21 Citations (Scopus) -
Preparation of fluorescence quenched libraries containing interchain disulphide bonds for studies of protein disulphide isomerases
Spetzler, J. C., Westphal, V., Winther, J. R. & Meldal, M., 1998, In: Journal of Peptide Science. 4, 2, p. 128-37 10 p.Research output: Contribution to journal › Journal article › Research › peer-review