Research output per year
Research output per year
Personal profile
Short presentation
Forskningsfelt
Mit primære forsknings område består i at udvikle assays til at undersøge toksikologiske effekter af nanopartikler. Mine studier har bragt mig vidt omkring indenfor såvel in vivo som in vitro toksikologi.
Nuværende forskning
Fokus for min nuværende forskning er primært udvikling og optimering af cellebaserede assays, hvor formålet er at undersøge celle-celle interaktioner og teste, om man kan få mere eller bedre information ud af at blande forskellige typer af celler i en co-kultur. Testsystemerne bruges til at undersøge toksikologiske effekter af forskellige typer forbrændingspartikler, hovedsagelig fokuseret på luftforureningspartikler i form af dieselpartikler, men også på brænderøgspartikler og andre typer af nanopartikler. Mine primære interesser er interaktionen mellem partikler og celler, samt sammenhængen mellem partikel induceret oksidativt stress og inflammation samt DNA skader i cellerne.
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Nanotoksikologi
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Nanomedicin
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co-kulturer
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Oksidativt stress
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DNA skader
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Celle-celle interaktioner
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Celle-partikel interaktioner
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Pulmonære effekter
- Kardiovaskulære effekter
Keywords
- Faculty of Health and Medical Sciences
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Dive into the research topics where Martin Roursgaard is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 6 Similar Profiles
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Effects of alcohol consumption on the allergen-specific immune response in mice
Linneberg, A., Roursgaard, M., Hersoug, L.-G. & Larsen, S. T., 2008, In: Alcoholism: Clinical and Experimental Research. 32, 3, p. 553-557 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of vitamin C and iron chelation on diesel exhaust particle and carbon black induced oxidative damage and cell adhesion molecule expression in human endothelial cells
Frikke-Schmidt, H. R., Roursgaard, M., Lykkesfeldt, J., Loft, S., Nøjgaard, J. K. & Møller, P., 24 Jun 2011, In: Toxicology Letters. 203, 3, p. 181-189 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oxidative stress, genotoxicity, and vascular cell adhesion molecule expression in cells exposed to particulate matter from combustion of conventional diesel and methyl ester biodiesel blends
Hemmingsen, J. G., Møller, P., Nøjgaard, J. K., Roursgaard, M. & Loft, S., 1 Oct 2011, In: Environmental Science & Technology (Washington). 45, 19, p. 8545-51 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Urinary excretion of 8-oxo-7,8-dihydroguanine as biomarker of oxidative damage to DNA
Loft, S., Danielsen, P. H., Løhr, M., Jantzen, K., Hemmingsen, J. G., Roursgaard, M., Karottki, D. G. & Møller, P., 15 Feb 2012, In: Archives of Biochemistry and Biophysics. 518, 2, p. 142-50 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Transport of SiO(2) Nanoparticles through Human Skin
Staronová, K., Nielsen, J. B., Roursgaard, M. & Knudsen, L. E., Aug 2012, In: Basic & Clinical Pharmacology & Toxicology Online. 111, 2, p. 142-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Expression of adhesion molecules, monocyte interactions and oxidative stress in human endothelial cells exposed to wood smoke and diesel exhaust particulate matter
Forchhammer, L., Loft, S., Roursgaard, M., Cao, Y., Riddervold, I. S., Sigsgaard, T. & Møller, P., 7 Mar 2012, In: Toxicology Letters. 209, 2, p. 121-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Carbon black nanoparticles and vascular dysfunction in cultured endothelial cells and artery segments
Vesterdal, L. K., Mikkelsen, L., Folkmann, J. K., Sheykhzade, M., Cao, Y., Roursgaard, M., Loft, S. & Møller, P., 2 Oct 2012, In: Toxicology Letters. 214, 1, p. 19-26 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oxidative damage to DNA by diesel exhaust particle exposure in co-cultures of human lung epithelial cells and macrophages
Jantzen, K., Roursgaard, M., Madsen, C. D., Loft, S., Rasmussen, L. J. & Møller, P., Nov 2012, In: Mutagenesis. 27, 6, p. 693-701 9 p.Research output: Contribution to journal › Journal article › Research › peer-review