Research output per year
Research output per year
Personal profile
Short presentation
Research area
Circadian rhythms are endogenous rhythms with a 24-hour period that enable living organisms to synchronize biological functions to the ambient light regime. In the mammalian brain circadian rhythms are regulated by the photoneuroendocrine system consisting of the suprachiasmatic nucleus of hypothalamus, the pineal gland and the retina. In a combined effort involving neuroanatomical and molecular biological techniques, we are studying development and function of the circadian system of the mammalian brain.
Research group
Associate professor Martin Fredensborg Rath, PhD
Postdoc Tenna Bering, PhD
PhD-student Mikkel Bloss Carstensen, MSc
PhD-sudent Henrik Hertz, MSc
Lab technician Rikke Lundorf, BMLT
CV
Academic degrees
2005: MSc in Human Biology, University of Copenhagen
2009: PhD in Medical Sciences, University of Copenhagen
Selected academic positions
2004-2007:Visiting research associate, Section on Neuroendocrinology (PI: Dr. David C. Klein), NICHD, National Institutes of Health (NIH), Bethesda, MD, USA
2009-2011, 2012-2013: Postdoc, Department of Neuroscience and Pharmacology (DNP), University of Copenhagen (UCPH).
2011-2012: Research associate professor (fixed-term employment), DNP, UCPH.
2013-2014: Assistant professor (tenure-track), DNP, UCPH.
2014- : Associate professor (tenure), DNP, UCPH.
Academic assessments of qualifications
2016: Full professor qualified, Aarhus University
2019: Full professor qualified, University of Southern Denmark
Selected grants (> 200,000 USD per grant)
2009-2012: The Danish Council for Independent Research
2010-2013: The Lundbeck Foundation
2013-2015: The Lundbeck Foundation
2015-2017: The Novo Nordisk Foundation
2018-2020: The Novo Nordisk Foundation
2018-2021: The Danish Council for Independent Research
A total of > 2 M USD in external grants.
Other funding providers
2007-2008: The Danish Council for Independent Research
2015-2016: Brødrene Hartmanns Fond
2015-2016: Agnes og Poul Friis’ Fond
2015-2016: Beckett Fonden
2016-2017: Carlsberg Foundation
2018-2019: Carlsberg Foundation
Selected invited talks
2007: Workshop on the Biology of Pax4, NIH, Bethesda, MD, USA.
2008: Gordon Research Conference on Pineal Cell Biology, Lucca, Italy.
2010: Gordon Research Conference on Pineal Cell Biology, Galveston, TX, USA.
2013: XII Latin-American Symposium of Chronobiology, Mendoza, Argentina.
2016: Society for Biological Rhythms, Columbia University, NYC, USA.
Selected teaching and examination
2009-: Neuroanatomy, gross anatomy and embryology for medical students
2010-: Neuroanatomy of the Laboratory Animal for PhD-students
2011-: Director of Molecular Methods in Neuroanatomy for PhD-students
2013-2014: Assistant professor training
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Keywords
- Faculty of Health and Medical Sciences
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- 6 Similar Profiles
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The Lhx4 homeobox transcript in the rat pineal gland: Adrenergic regulation and impact on transcripts encoding melatonin-synthesizing enzymes
Hertz, H., Carstensen, M. B., Bering, T., Rohde, K., Møller, M., Granau, A. M., Coon, S. L., Klein, D. C. & Rath, M. F., 1 Jan 2020, In: Journal of Pineal Research (Print). 68, 1, e12616.Research output: Contribution to journal › Journal article › Research › peer-review
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Homeobox genes in melatonin-producing pinealocytes: Otx2 and Crx act to promote hormone synthesis in the mature rat pineal gland.
Rohde, K., Hertz, H. & Rath, M. F., May 2019, In: Journal of Pineal Research (Print). 66, 4, 11 p., e12567.Research output: Contribution to journal › Journal article › Research › peer-review
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MobiSeq: De novo SNP discovery in model and non-model species through sequencing the flanking region of transposable elements
Rey-Iglesia, A., Gopalakrishan, S., Carøe, C., Alquezar-Planas, D. E., Ahlmann Nielsen, A., Röder, T., Pedersen, L. B., Næsborg-Nielsen, C., Sinding, M-H. S., Rath, M. F., Li, Z., Petersen, B., Gilbert, M. T. P., Bunce, M., Mourier, T. & Hansen, A. J., Mar 2019, In: Molecular Ecology Resources. 19, 2, p. 512-525 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Single Cell Sequencing of the Pineal Gland: The Next Chapter
Coon, S. L., Fu, C., Hartley, S. W., Holtzclaw, L., Mays, J. C., Kelly, M. C., Kelley, M. W., Mullikin, J. C., Rath, M. F., Savastano, L. E. & Klein, D. C., 20 Sept 2019, In: Frontiers in Endocrinology. 10Research output: Contribution to journal › Review › peer-review
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Cerebral influx of Na+ and Cl- as the osmotherapy-mediated rebound response in rats
Oernbo, E. K., Lykke, K., Steffensen, A. B., Töllner, K., Kruuse, C., Rath, M. F., Löscher, W. & MacAulay, N., 2018, In: Fluids and Barriers of the CNS. 15, 14 p., 27.Research output: Contribution to journal › Journal article › Research › peer-review
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Døgnrytmer, menneskets biologiske adaptation til den roterende klode
Møller, M. & Rath, M. F., 2018, In: Ugeskrift for Laeger. 180, 36, V70091.Research output: Contribution to journal › Editorial
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Single-cell RNA sequencing of the mammalian pineal gland identifies two pinealocyte subtypes and cell type-specific daily patterns of gene expression
Mays, J. C., Kelly, M. C., Coon, S. L., Holtzclaw, L., Rath, M. F., Kelley, M. W. & Klein, D. C., 2018, In: PLOS ONE. 13, 10, 22 p., e0205883.Research output: Contribution to journal › Journal article › Research › peer-review
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Spinal dorsal horn astrocytes release GABA in response to synaptic activation
Christensen, R. K., Delgado-Lezama, R., Russo, R. E., Lind, B. L., Alcocer, E. L., Rath, M. F., Fabbiani, G., Schmitt, N., Lauritzen, M., Petersen, A. V., Carlsen, E. M. & Perrier, J-F., 2018, In: The Journal of Physiology. 596, 20, p. 4983-4994 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Development and identification of the melatonin-producing pinealocyte
Martin Fredensborg Rath (Lecturer)
30 Jun 2016Activity: Talk or presentation types › Lecture and oral contribution
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Circadiane rytmer i gnaverhjernen: Lokalisation og regulation af perifere klokker i cortex cerebri og cerebellum
Martin Fredensborg Rath (Lecturer)
14 Nov 2014Activity: Talk or presentation types › Lecture and oral contribution
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Journal of Biomedicine and Biotechnology (Journal)
Martin Fredensborg Rath (Editor)
2014Activity: Publication peer-review and editorial work types › Editor of Research journal › Research
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Homeobox genes in the rodent pineal gland: from development to phenotype maintenance
Martin Fredensborg Rath (Lecturer)
1 Nov 2013Activity: Talk or presentation types › Lecture and oral contribution
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Homeobox genes in the developing and adult pineal gland
Martin Fredensborg Rath (Lecturer)
8 Feb 2010Activity: Talk or presentation types › Lecture and oral contribution
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Regulation of Pax4 in the pineal gland and retina
Martin Fredensborg Rath (Lecturer)
16 Oct 2008Activity: Talk or presentation types › Lecture and oral contribution
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Expression and regulation of the Pax4 homeobox gene in the pineal and retina
Martin Fredensborg Rath (Lecturer)
5 May 2008Activity: Talk or presentation types › Lecture and oral contribution
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Developmental and diurnal dynamics of Pax4 expression in the rat pineal gland and retina
Martin Fredensborg Rath (Lecturer)
23 Apr 2008Activity: Talk or presentation types › Lecture and oral contribution