Leif Søndergaard

Research output

Research output per year 1991 1993 1994 1995 1998 2016

• 22 Journal article
• 8 Book chapter
• 1 Conference article

Research output per year

Research output per year

Search results

• 2016

  Isolation of a novel protein, P12-from adult Drosophila melanogaster that inhibits deoxyribonucleoside and protein kinase activities and activates 3'-5'-exonuclease activity

  Christiansen, L. S., Zanten, G. V., Berenstein, D., Lauridsen, M., Kjærulff, S., Søndergaard, L. & Munch-Petersen, B., 1 Dec 2016, In: Nucleosides, Nucleotides and Nucleic Acids. 35, 10-12, p. 699-706 8 p.

  Research output: Contribution to journal › Conference article › Research › peer-review

  • deoxyribonucleoside kinases 100%
  • Deoxyribonucleoside 74%
  • Exonucleases 72%
  • Drosophila melanogaster 59%
  • Diptera 58%
• 2015

  CCHamide-2 is an orexigenic brain-gut peptide in Drosophila

  Ren, G. R., Hauser, F., Rewitz, K. F., Kondo, S., Engelbrecht, A. F., Didriksen, A. K., Schjøtt, S. R., Sembach, F. E., Li, S., Søgaard, K. C., Søndergaard, L. & Grimmelikhuijzen, C., 13 Jul 2015, In: PLOS ONE. 10, 7, 18 p., e0133017.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Drosophilidae 100%
  • Peptides 95%
  • Mutant 84%
  • Brain 73%
  • mutant 71%
  46 Citations (Scopus)

  500 Downloads (Pure)
• 2013

  Two types of muscarinic acetylcholine receptors in Drosophila and other arthropods: [plus] Erratum

  Collin, C. A., Hauser, F., Gonzalez de Valdivia, E. I., Li, S., Reisenberger, J., Carlsen, E. M. M., Khan, Z., Hansen, N. Ø., Puhm, F., Søndergaard, L., Niemiec, J., Heninger, M., Ren, G. R. & Grimmelikhuijzen, C., Sept 2013, In: Cellular and Molecular Life Sciences. 70, 17, p. 3231-3242 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Arthropods 100%
  • Muscarinic Receptors 85%
  • Drosophila 72%
  • Muscarine 44%
  • Quinuclidinyl Benzilate 29%
  40 Citations (Scopus)
• 2004

  Characterization of low-glycosylated forms of soluble human urokinase receptor expressed in Drosophila Schneider 2 cells after deletion of glycosylation-sites

  Gårdsvoll, H., Werner, F., Søndergaard, L., Danø, K. & Ploug, M., 2004, In: Protein Expression and Purification. 34, 2, p. 284-295 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Urokinase-Type Plasminogen Activator 100%
  • Urokinase Plasminogen Activator Receptors 98%
  • Glycosylation 90%
  • Drosophila 81%
  • Cricetulus 37%
  50 Citations (Scopus)
• 2003

  Molecular cloning, functional expression, and gene silencing of two Drosophila receptors for the Drosophila neuropeptide pyrokinin-2.

  Rosenkilde, C., Cazzamali, G., Williamson, M., Hauser, F., Søndergaard, L., DeLotto, R. & Grimmelikhuijzen, C. J. P., 2003, In: Biochemical and Biophysical Research Communications. 309, 2, p. 485-94 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • pyrokinin 100%
  • Neuropeptide Receptors 72%
  • Sex Pheromone 67%
  • Molecular Cloning 56%
  • Gene Silencing 51%
  73 Citations (Scopus)

• Mosquito has a single multisubstrate deoxyribonucleoside kinase characterized by unique substrate specificity.

  Knecht, W., Petersen, B. E., Sandrini, M. P. B., Søndergaard, L., Munch-Petersen, B. & Piskur, J., 2003, In: Nucleic Acids Research. 31, p. 1665-1672

  Research output: Contribution to journal › Journal article › Research › peer-review

  19 Citations (Scopus)
• 2002

  A functional and structural basis for TCR cross-resctivity in multiple sclerosis

  Lang, H. L. E., Jacobsen, H., Ikemizu, S., Andersson, C., Harlos, K., Madsen, L., Hjorth, P., Søndergaard, L., Svejgaard, A., Wucherpfennig, K., Stuart, D. I., Bell, J. I., Jones, Y. & Fugger, L., 2002, In: Nature Immunology. 3, 10, p. 940-943

  Research output: Contribution to journal › Journal article › Research › peer-review

  • T-Cell Antigen Receptor 100%
  • Multiple Sclerosis 86%
  • Myelin Basic Protein 59%
  • Major Histocompatibility Complex 50%
  • Human Herpesvirus 4 48%
  431 Citations (Scopus)

• Molecular identification of the insect adipokinetic hormone receptors.

  Staubli, F., Jørgensen, T. J. D., Cazzamali, G., Williamson, M., Lenz, C., Søndergaard, L., Roepstorff, P. & Grimmelikhuijzen, C. J. P., 2002, In: Proceedings of the National Academy of Science of the United States of America. 99, 6, p. 3446-51 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Insect Hormones 100%
  • adipokinetic hormone 99%
  • Insecta 28%
  • Bombyx 25%
  • Sugars 17%
  234 Citations (Scopus)
• 2000

  Functional expression of a multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster and its C-terminal deletion mutants

  Munch-Petersen, B., Knecht, W., Lenz, C., Søndergaard, L. & Piskur, J., 2000, In: The Journal of Biological Chemistry. 275 (9), p. 6673-6679

  Research output: Contribution to journal › Journal article › Research › peer-review

• Molecular cloning, genomic organization, developmental regulation, and a knock-out mutant of a novel leu-rich repeats-containing G protein-coupled receptor (DLGR-2) from Drosophila melanogaster.

  Eriksen, K. K., Hauser, F., Schiøtt, M., Pedersen, K-M., Søndergaard, L. & Grimmelikhuijzen, C., 2000, In: Genome Research. 10, 7, p. 924-938

  Research output: Contribution to journal › Journal article › Research › peer-review

  • CCR10 Receptors 100%
  • Molecular Cloning 67%
  • Drosophila melanogaster 62%
  • Introns 55%
  • Glycoproteins 36%
  58 Citations (Scopus)
• 1998

  Four Deoxynucleoside Kinase Activities from Drosophila melanogaster Are Contained within a Single Monomeric Enzyme, a New Multifunctional Deoxynucleoside Kinase

  Munch-Petersen, B., Piskur, J. & Søndergaard, L., 1998, In: The Journal of Biological Chemistry. 273 (7), p. 3926-3931

  Research output: Contribution to journal › Journal article › Research

  86 Citations (Scopus)

• Functional characterization of HLA-DRA1*0101/ DRB1*0401 molecules expressed in Drosophila melanogaster cells

  Hansen, B. E., Andersson, E. C., Madsen, L. S., Engberg, J., Søndergaard, L., Svejgaard, A. & Flugger, L., 1998, In: HLA. 51, p. 119-128

  Research output: Contribution to journal › Journal article › Research

  16 Citations (Scopus)

• Molecular Cloning, Genomic Organization and Developmental Regulation of a Novel Receptor from Drosophila melanogaster Structurally Related to Gonadotropin-Releasing Hormone Receptors from Vertebrates

  Hauser, F., Søndergaard, L. & Grimmelikhuijzen, C. J. P., 28 Aug 1998, In: Biochemical and Biophysical Research Communications. 249, 3, p. 822-828

  Research output: Contribution to journal › Journal article › Research › peer-review

  • LHRH Receptors 100%
  • Developmental 86%
  • Molecular Cloning 83%
  • Drosophila melanogaster 78%
  • Vertebrates 64%
  81 Citations (Scopus)

• The single deoxynucleoside kinase in Drosophila melanogaster, Dm-dNK, is multifunctional and differs from the mammalian deoxynucleoside kinases (Chapt. 92)

  Munch-Petersen, B., Piskur, J. & Søndergaard, L., 1998, Advances in Experimental Medicine and Biology, Volume 431: "Purine and Pyrimidine Metabolism in Man IX". New York, USA: Plenum Publishing Corporation, p. 465-469

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
• 1997

  Comparison of pyrimidine nucleoside salvage enzymes in Drosophila melanogaster and man

  Munch-Petersen, B., Piskur, J. & Søndergaard, L., 1997, In: Clinical Biochemistry. Vol. 30, p. 28-29

  Research output: Contribution to journal › Journal article › Research
• 1996

  Characterization of HLA-DRB1*0401 molecules expressed in Drosophila Schneider cells

  Hansen, B., Andersson, C., Madsen, L., Søndergaard, L., Fugger, L. & Svejlgaard, A., 1996, In: Human Immunology. 47 (1-2), p. 129

  Research output: Contribution to journal › Journal article › Research
• 1995

  Genetic aspects of beta-alanine metabolism in the fruit fly and yeast

  Piskur, J., Hermansen, T. D., Gojkovic, Z., Meyer, E., Saillard, J., Bahn, E. & Søndergaard, L., 1995, In: Amino Acids. 9, p. 57-58

  Research output: Contribution to journal › Journal article › Research

• Nutritional response in a Drosophila yolk protein gene promoter

  Søndergaard, L., Mauchline, D., Egetoft, P., White, N., Wulff, P. & Bownes, M., 1995, In: Mol. Gen. Genet.. 248, p. 25-32

  Research output: Contribution to journal › Journal article › Research

  20 Citations (Scopus)

• Observed resistance to pyrimidine analogs and sensitivity to uracil in Drosophila is attributed to deregulation of pyrimidine metabolism

  Piskur, J., Søndergaard, L., Gojkovic, Z., Stokbro, B., Hjulsager, C., Davidson, J., DeMoll, E., Rawls, J. & Bahn, E., 1995, Purine and Pyrimidine Metabolism in Man VIII. Advances in Experimental Medicine and Biology, Vol 370. New York: Plenum Publishing Corporation, p. 559-565

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  4 Citations (Scopus)
• 1994

  Genetic and biochemical analysis of Drosophila mutants having deregulated pyrimidine metabolism. Abstract Nordic Drosophil. Meeting 1994

  Piskur, J., Gojkovic, Z., Søndergaard, L. & Bahn, E., 1994, In: Yichuan. 121, p. 115

  Research output: Contribution to journal › Journal article › Research

• Genetic bases for the regulation of pyrimidine metabolism. Abstr. 8th Intern.Symp. Purine and Pyrimidine Metabolism, 22.-27. maj 1994

  Piskur, J., Bahn, E., Hjulsager, C., Stokbro, B. & Søndergaard, L., 1994, Eight International Symposium on Purine and Pyrimidine Metabolism in Man. Abstracts. Bloomington, Indiana, USA, p. 61 (109)

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

• Morphology of Drosophila S-2 cells in different culture conditions

  Søndergaard, L., 1994, In: In Vitro Cell.Dev.Biol.. 30A, p. 18-20

  Research output: Contribution to journal › Journal article › Research

  6 Citations (Scopus)

• Nested arrangement in the D. melanogaster rudimentary gene. Abstract Nordic Drosophila Meeting 1994

  Hjulsager, C., Piskur, J. & Søndergaard, L., 1994, In: Yichuan. 121, p. 116

  Research output: Contribution to journal › Journal article › Research
• 1993

  Cis-regulatory sequences leading to female-specific expression of yolk protein genes 1 and 2 in the fat body of Drosophila melanogaster

  Abrahamsen, N., Martinez, A., Kjær, T., Søndergaard, L. & Bownes, M., 1993, In: MGG. 237, p. 41-48

  Research output: Contribution to journal › Journal article › Research

  26 Citations (Scopus)

• Homology between the mammalian liver and the Drosophila fat body

  Søndergaard, L., 1993, In: TIG. Vol 9, No. 6, p. 193

  Research output: Contribution to journal › Journal article › Research

  69 Citations (Scopus)

• Studies of the food response of the yolk protein genes in D. melanogaster. Abstr. 13th European Drosophila Research Conference, Kreta, Grækenland, d.12.-17. September 1993

  Søndergaard, L., Egetoft, P., Lund, O., Mauchline, D. & Bownes, M., 1993, Abstract Book 13th EDRC. Kreta, Grækenland, p. G7

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

• The dominant mutation Suppressor of black indicates that de novo pyrimindine biosynthesis is involved in the Drosophila tan pigmentation pathway

  Piskur, J., Kolbak, D., Søndergaard, L. & Pedersen, M. B., 1993, In: Mol. Gen. Genet.. 241, p. 335-340

  Research output: Contribution to journal › Journal article › Research

• The dominant suppressor of black indicates that de novo pyrimidine biosynthesis is involved in the Drosophila tan pigmentation pathway. Abstr. 13th Eur.Drosophila Res.Conf.,Kreta,Grækenl. 12-17.9.93

  Piskur, J., Kolbak, D., Søndergaard, L. & Pedersen, M. B., 1993, Abstract Book 13th EDRC. Kreta, Grækenland, p. F4

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
• 1992

  A novel gene within an intron of the rudimentary gene in Drosophila melanogaster. Abstract. Sixth Harden Satellite Meeting, Glasgow, UK, 12.-14. sept. 1992

  Søndergaard, L. & Hjulsager, C., 1992, The Genes and Enzymes of Pirimidine Biosynthesis. Abstract Book. Glasgow, p. 53-M4

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
• 1991

  Drosophila cell cultures as an expression system for foreign genes

  Søndergaard, L., 1991, Abstract Book 12th EDRC Mainz. Tyskland, p. 314

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

• Sex and tissue specific regulation of the yp1-2 genes of Drosophila

  Abrahamsen, N., Martinez, A., Bownes, M., Kjær, T. & Søndergaard, L., 1991, Abstract Book 12th EDRC Mainz. Tyskland, p. 79

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research