Jens D. Mikkelsen

2013

The effect of perinatal exposure to ethinyl oestradiol or a mixture of endocrine disrupting pesticides on kisspeptin neurons in the rat hypothalamus

Overgaard, A., Holst, K., Mandrup, K., Boberg, J., Christiansen, S., Jacobsen, A. P., Hass, U. & Mikkelsen, J. D., 2013, In: NeuroToxicology. 37, p. 154-162 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

The mGlu2/3 Receptor Agonists LY354740 and LY379268 Differentially Regulate Restraint-Stress-Induced Expression of c-Fos in Rat Cerebral Cortex

Menezes, M. M., Santini, M., Benvega, M. J., Marek, G. J., Merchant, K. M., Mikkelsen, J. D. & Svensson, K. A., 2013, In: Neuroscience Journal. 2013, 8 p., 736439.

Research output: Contribution to journal › Journal article › Research › peer-review

2012

Epigenetic regulation of Arc and c-Fos in the hippocampus after acute electroconvulsive stimulation in the rat.

Dyrvig, M., Hansen, H. H., Christiansen, S. H. O., Woldbye, D. P. D., Mikkelsen, J. D. & Lichota, J., 1 Aug 2012, In: Brain Research Bulletin. 88, p. 507-13 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

35 Citations (Scopus)

Reprogrammering af modne celler til neuroner

Translated title of the contribution: Reprogramming of adult cells to neuronsMikkelsen, J. D., Rasmussen, M. A., Meyer, M. & Knudsen, G. M., 2012, In: Ugeskrift for Laeger. 174, 12, p. 786

Research output: Contribution to journal › Journal article › Research › peer-review

The α7 nicotinic acetylcholine receptor complex: one, two or multiple drug targets?

Thomsen, M. S. & Mikkelsen, J. D., May 2012, In: Current Drug Targets. 13, 5, p. 707-20 14 p.

Research output: Contribution to journal › Journal article › Research

28 Citations (Scopus)

The α7 nicotinic acetylcholine receptor ligands methyllycaconitine, NS6740 and GTS-21 reduce lipopolysaccharide-induced TNF-α release from microglia

Thomsen, M. S. & Mikkelsen, J. D., 15 Oct 2012, In: Journal of Neuroimmunology. 251, 1-2, p. 65-72 8 p.

Research output: Contribution to journal › Journal article › Research

82 Citations (Scopus)

Transient inactivation of the neonatal ventral hippocampus impairs attentional set-shifting behavior: reversal with an α7 nicotinic agonist

Brooks, J. M., Pershing, M. L., Thomsen, M. S., Mikkelsen, J. D., Sarter, M. & Bruno, J. P., Oct 2012, In: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 37, 11, p. 2476-86 11 p.

Research output: Contribution to journal › Journal article › Research

38 Citations (Scopus)

Type I and II positive allosteric modulators differentially modulate agonist-induced up-regulation of α7 nicotinic acetylcholine receptors

Thomsen, M. S. & Mikkelsen, J. D., Oct 2012, In: Journal of Neurochemistry. 123, 1, p. 73-83 11 p.

Research output: Contribution to journal › Journal article › Research

28 Citations (Scopus)

2011

Differential immediate and sustained memory enhancing effects of alpha7 nicotinic receptor agonists and allosteric modulators in rats

Thomsen, M. S., El-Sayed, M. & Mikkelsen, J. D., 9 Nov 2011, In: PLOS ONE. 6, 11, p. e27014

Research output: Contribution to journal › Journal article › Research

43 Citations (Scopus)

Hippocampal α7 nicotinic acetylcholine receptor levels in patients with schizophrenia, bipolar disorder, or major depressive disorder

Thomsen, M. S., Weyn, A. & Mikkelsen, J. D., Nov 2011, In: Bipolar Disorders (English Edition, Online). 13, 7-8, p. 701-7 7 p.

Research output: Contribution to journal › Journal article › Research

32 Citations (Scopus)

2010

Distinct neural pathways mediate alpha7 nicotinic acetylcholine receptor-dependent activation of the forebrain

Thomsen, M. S., Hay-Schmidt, A., Hansen, H. H. & Mikkelsen, J. D., Sept 2010, In: Cerebral Cortex. 20, 9, p. 2092-102 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

21 Citations (Scopus)

Distinct neural pathways mediate Î±7 nicotinic acetylcholine receptor-dependent activation of the forebrain

Thomsen, M. S., Hay-Schmidt, A., Hansen, H. H. & Mikkelsen, J. D., 2010, In: Cerebral Cortex. 20, 9, p. 2092-102

Research output: Contribution to journal › Journal article › Research › peer-review

Plaque deposition dependent decrease in 5-HT2A serotonin receptor in AbetaPPswe/PS1dE9 amyloid overexpressing mice

Holm, P., Ettrup, A., Klein, A. B., Santini, M. A., El-Sayed, M., Elvang, A. B., Stensbøl, T. B., Mikkelsen, J. D., Knudsen, G. M. & Kleijn, S. A., 1 Jan 2010, In: Journal of Alzheimer's Disease. 20, 4, p. 1201-13 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

21 Citations (Scopus)

Regulation of brain-derived neurotrophic factor (BDNF) in the chronic unpredictable stress rat model and the effects of chronic antidepressant treatment

Larsen, M. H., Mikkelsen, J. D., Hay-Schmidt, A. & Sandi, C., Oct 2010, In: Journal of Psychiatric Research.

Research output: Contribution to journal › Journal article › Research › peer-review

122 Citations (Scopus)

2009

alpha(7) Nicotinic acetylcholine receptor activation prevents behavioral and molecular changes induced by repeated phencyclidine treatment

Thomsen, M. S., Christensen, D. Z., Hansen, H. H., Redrobe, J. P. & Mikkelsen, J. D., 2009, In: Neuropharmacology. 56, 6-7, p. 1001-9 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

68 Citations (Scopus)

BDNF downregulates 5-HT(2A) receptor protein levels in hippocampal cultures

Trajkovska, V., Santini, M. A., Marcussen, A. B., Thomsen, M. S., Hansen, H. H., Mikkelsen, J. D., Arneberg, L., Kokaia, M., Knudsen, G. M. & Aznar, S., 2009, In: Neurochemistry International. 55, 7, p. 697-702 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

Circadian and developmental regulation of N-methyl-d-aspartate-receptor 1 mRNA splice variants and N-methyl-d-aspartate-receptor 3 subunit expression within the rat suprachiasmatic nucleus

Bendová, Z., Sumová, A. & Mikkelsen, J. D., 2009, In: Neuroscience. 159, 2, p. 599-609 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

Discovery of a new class of potential multifunctional atypical antipsychotic agents targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors: design, synthesis, and effects on behavior

Butini, S., Gemma, S., Campiani, G., Franceschini, S., Trotta, F., Borriello, M., Ceres, N., Ros, S., Coccone, S. S., Bernetti, M., De Angelis, M., Brindisi, M., Nacci, V., Fiorini, I., Novellino, E., Cagnotto, A., Mennini, T., Sandager-Nielsen, K., Andreasen, J. T. & Scheel-Kruger, J. & 2 others, Mikkelsen, J. D. & Fattorusso, C., 2009, In: Journal of Medicinal Chemistry. 52, 1, p. 151-69 18 p.

Research output: Contribution to journal › Journal article › Research › peer-review

73 Citations (Scopus)

Melatonin controls seasonal breeding by a network of hypothalamic targets

Revel, F. G., Masson-Pévet, M., Pévet, P., Mikkelsen, J. D. & Simonneaux, V., 2009, In: Neuroendocrinology. 90, 1, p. 1-14 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

61 Citations (Scopus)

Selective cognitive deficits and reduced hippocampal brain-derived neurotrophic factor mRNA expression in small-conductance calcium-activated K+ channel deficient mice

Jacobsen, J. P. R., Redrobe, J. P., Hansen, H. H., Petersen, S., Bond, C. T., Adelman, J. P., Mikkelsen, J. D. & Mirza, N. R., 2009, In: Neuroscience. 163, 1, p. 73-81 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

20 Citations (Scopus)

2008

Kisspeptin and the seasonal control of reproduction in hamsters

Simonneaux, V., Ansel, L., Revel, F. G., Klosen, P., Pévet, P. & Mikkelsen, J. D., 2008, In: Peptides. 30, 1, p. 146-53 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

79 Citations (Scopus)

Response of substances co-expressed in hypothalamic magnocellular neurons to osmotic challenges in normal and Brattleboro rats

Bundzikova, J., Pirnik, Z., Zelena, D., Kiss, A. & Mikkelsen, J. D., 2008, In: Cellular & Molecular Neurobiology. 28, 8, p. 1033-1047 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

33 Citations (Scopus)

The neuroanatomy of the kisspeptin system in the mammalian brain

Mikkelsen, J. D. & Simonneaux, V., 2008, In: Peptides. 30, 1, p. 26-33 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

101 Citations (Scopus)

The nicotinic alpha7 acetylcholine receptor agonist ssr180711 is unable to activate limbic neurons in mice overexpressing human amyloid-beta1-42

Søderman, A., Thomsen, M. S., Hansen, H. H., Nielsen, E. Ø., Jensen, M. S., West, M. J. & Mikkelsen, J. D., 28 Aug 2008, In: Brain Research. 1227, p. 240-7 8 p.

Research output: Contribution to journal › Journal article › Research

25 Citations (Scopus)

The selective alpha7 nicotinic acetylcholine receptor agonist A-582941 activates immediate early genes in limbic regions of the forebrain: Differential effects in the juvenile and adult rat

Thomsen, M. S., Mikkelsen, J. D., Timmermann, D. B., Peters, D. A., Hay-Schmidt, A., Martens, H. A., Hansen, H. H. & Thomsen, M. S., 23 Jun 2008, In: Neuroscience. 154, 2, p. 741-53 13 p.

Research output: Contribution to journal › Journal article › Research

26 Citations (Scopus)

2007

The alpha7 nicotinic receptor agonist SSR180711 increases activity regulated cytoskeleton protein (Arc) gene expression in the prefrontal cortex of the rat

Kristensen, S., Thomsen, M. S., Hansen, H. H., Timmermann, D. B., Hay-Schmidt, A. & Mikkelsen, J. D., 17 May 2007, In: Neuroscience Letters. 418, 2, p. 154-8 5 p.

Research output: Contribution to journal › Journal article › Research

24 Citations (Scopus)

2005

Modulation of anxiety circuits by serotonergic systems

Lowry, C. A., Johnson, P. L., Hay-Schmidt, A., Mikkelsen, J. & Shekhar, A., Dec 2005, In: Stress: The International Journal on the Biology of Stress . 8, 4, p. 233-246 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

222 Citations (Scopus)

Serotonergic systems associated with arousal and vigilance behaviors following administration of anxiogenic drugs

Abrams, J. K., Johnson, P. L., Hay-Schmidt, A., Mikkelsen, J. D., Shekhar, A. & Lowry, C. A., 2005, In: Neuroscience. 133, 4, p. 983-97 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

161 Citations (Scopus)

2004

Serotonergic stimulation of the rat hypothalamo-pituitary-adrenal axis: interaction between 5-HT1A and 5-HT2A receptors

Mikkelsen, J. D., Hay-Schmidt, A. & Kiss, A., Jun 2004, In: Annals of the New York Academy of Sciences. 1018, p. 65-70 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

46 Citations (Scopus)

1994

Efferent connections from the lateral hypothalamic region and the lateral preoptic area to the hypothalamic paraventricular nucleus of the rat

Larsen, P. J., Hay-Schmidt, A. & Mikkelsen, J. D., 1994, In: Journal of Comparative Neurology. 342, 2, p. 299-319 21 p.

Research output: Contribution to journal › Journal article › Research › peer-review

47 Citations (Scopus)

Induced resistance in sugar beet against Cercospora beticola: Induction by dichloroisonicotinic acid is independent of chitinase and β-1,3-glucanase transcript accumulation

Nielsen, K. K., Bojsen, K., Collinge, D. B. & Mikkelsen, J. D., 1 Jan 1994, In: Physiological and Molecular Plant Pathology. 45, 2, p. 89-99 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

36 Citations (Scopus)

1991

Induction, purification and characterization of chitinase isolated from pea leaves inoculated with Ascochyta pisi

Vad, K., Mikkelsen, J. D. & Collinge, D. B., 1 Apr 1991, In: Planta. 184, 1, p. 24-29 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

35 Citations (Scopus)

1988

Immunohistochemical localisation and developmental aspects of epidermal growth factor in the rat

Raaberg, L., Nexo, E., Mikkelsen, J. D. & Poulsen, S. S., 1 Jul 1988, In: Histochemistry. 89, 4, p. 351-356 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

48 Citations (Scopus)

Jens D. Mikkelsen

Research output

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