Daniel Hargbøl Madsen

2019

Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins

Jürgensen, H. J., Nørregaard, K. S., Sibree, M. M., Santoni‑Rugiu, E., Madsen, D. H., Wassilew, K., Krustrup, D., Garred, P., Bugge, T. H., Engelholm, L. H. & Behrendt, N., 1 Jan 2019, In: Journal of Cell Biology. 218, 1, p. 333-349 17 p.

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

2017

Tumor-Associated Macrophages Derived from Circulating Inflammatory Monocytes Degrade Collagen through Cellular Uptake

Madsen, D. H., Jürgensen, H. J., Siersbæk, M. S., Kuczek, D. E., Grey Cloud, L., Liu, S., Behrendt, N., Grøntved, L., Weigert, R. & Bugge, T. H., 26 Dec 2017, In: Cell Reports. 21, 13, p. 3662-3671 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

45 Citations (Scopus)

73 Downloads (Pure)

2016

A CCR2 macrophage endocytic pathway mediates extravascular fibrin clearance in vivo

Motley, M. P., Madsen, D. H., Jürgensen, H. J., Spencer, D. E., Szabo, R., Holmbeck, K., Flick, M. J., Lawrence, D. A., Castellino, F. J., Weigert, R. & Bugge, T. H., 3 Mar 2016, In: Blood. 127, 9, p. 1085-1096 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

2015

The collagen receptor uPARAP/Endo180 in tissue degradation and cancer (Review)

Carlsen Melander, E. M., Jürgensen, H. J., Madsen, D. H., Engelholm, L. H. & Behrendt, N., 1 Oct 2015, In: International Journal of Oncology. 47, 4, p. 1177-88 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

25 Citations (Scopus)

13 Downloads (Pure)

2013

Differential actions of the endocytic collagen receptor uPARAP/Endo180 and the collagenase MMP-2 in bone homeostasis

Madsen, D. H., Jürgensen, H. J., Ingvarsen, S., Melander, M. C., Albrechtsen, R., Hald, A., Holmbeck, K., Bugge, T. H., Behrendt, N. & Engelholm, L. H., 5 Aug 2013, In: PloS one. 8, 8, p. e71261

Research output: Contribution to journal › Journal article › Research › peer-review

21 Citations (Scopus)

M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway

Madsen, D. H., Leonard, D., Masedunskas, A., Moyer, A., Jürgensen, H. J., Peters, D. E., Amornphimoltham, P., Selvaraj, A., Yamada, S. S., Brenner, D. A., Burgdorf, S., Engelholm, L. H., Behrendt, N., Holmbeck, K., Weigert, R. & Bugge, T. H., 16 Sept 2013, In: Journal of Cell Biology. 202, 6, p. 951-66 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

144 Citations (Scopus)

Targeting a single function of the multifunctional matrix metalloprotease MT1-MMP: impact on lymphangiogenesis

Ingvarsen, S., Porse, A., Erpicum, C., Maertens, L., Jürgensen, H. J., Madsen, D. H., Melander, M. C., Gårdsvoll, H., Høyer-Hansen, G., Noel, A., Holmbeck, K., Engelholm, L. H. & Behrendt, N., 12 Apr 2013, In: Journal of Biological Chemistry. 288, 15, p. 10195-204 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

41 Citations (Scopus)

2012

Inhibitory Monoclonal Antibodies against Mouse Proteases Raised in Gene-Deficient Mice Block Proteolytic Functions in vivo

Lund, I. K., Rasch, M. G., Ingvarsen, S., Pass, J., Madsen, D. H., Engelholm, L. H., Behrendt, N. & Høyer-Hansen, G., 2012, In: Frontiers in Pharmacology. 3, p. 122

Research output: Contribution to journal › Journal article › Research › peer-review

9 Citations (Scopus)

2011

A novel functional role of collagen glycosylation: interaction with the endocytic collagen receptor uPARAP/ENDO 180

Jürgensen, H. J., Madsen, D. H., Ingvarsen, S., Melander, M. C., Gårdsvoll, H., Patthy, L., Engelholm, L. H. & Behrendt, N., 16 Sept 2011, In: Journal of Biological Chemistry. 286, 37, p. 32736-48 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

55 Citations (Scopus)

The endocytic receptor uPARAP/Endo180 in collagen turnover and its importance in physiological and pathological processes

Madsen, D. H., 30 Sept 2011

Research output: Book/Report › Ph.D. thesis

The non-phagocytic route of collagen uptake: a distinct degradation pathway

Madsen, D. H., Ingvarsen, S., Jürgensen, H. J., Melander, M. C., Kjøller, L., Moyer, A., Honoré, C., Madsen, M. C., Garred, P., Burgdorf, S., Bugge, T. H., Behrendt, N. & Engelholm, L. H., 29 Jul 2011, In: The Journal of Biological Chemistry. 286, 30, p. 26996-7010 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

77 Citations (Scopus)

2009

The collagen receptor uPARAP/Endo180

Engelholm, L. H., Ingvarsen, S., Jürgensen, H. J., Hillig, T., Madsen, D. H., Nielsen, B. S. & Behrendt, N., 1 Jan 2009, In: Frontiers in Bioscience. 14, p. 2103-14 12 p.

Research output: Contribution to journal › Review › peer-review

2008

A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor

Hillig, T., Engelholm, L. H., Ingvarsen, S., Madsen, D. H., Gårdsvoll, H., Larsen, J. K., Ploug, M., Danø, K., Kjøller, L. & Behrendt, N., 30 May 2008, In: Journal of Biological Chemistry. 283, 22, p. 15217-15223 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

26 Citations (Scopus)

Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72-kDa gelatinase MMP-2 on fibroblasts and fibrosarcoma cells

Ingvarsen, S., Madsen, D. H., Hillig, T., Lund, L. R., Holmbeck, K., Behrendt, N. & Engelholm, L. H., Jul 2008, In: Biological Chemistry. 389, 7, p. 943-953

Research output: Contribution to journal › Journal article › Research › peer-review

2007

Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation

Madsen, D. H., Engelholm, L. H., Ingvarsen, S., Hillig, T., Wagenaar-Miller, R. A., Kjøller, L., Gårdsvoll, H., Høyer-Hansen, G., Holmbeck, K., Bugge, T. H. & Behrendt, N., 14 Sept 2007, In: The Journal of Biological Chemistry. 282, 37, p. 27037-45 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

96 Citations (Scopus)

Increased expression of the collagen internalization receptor uPARAP/Endo180 in the stroma of head and neck cancer

Sulek, J., Wagenaar-Miller, R. A., Shireman, J., Molinolo, A., Madsen, D. H., Engelholm, L. H., Behrendt, N. & Bugge, T. H., Apr 2007, In: Journal of Histochemistry and Cytochemistry. 55, 4, p. 347-53 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

43 Citations (Scopus)

Daniel Hargbøl Madsen

Research output

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