Claire Francesca Meehan

Research output

Research output per year 2004 2007 2010 2011 2013 2014 2015 2017 2018

• 18 Journal article
• 3 Article in proceedings
• 2 Book chapter
• 1 Paper

Research output per year

Research output per year

Search results

• 2018

  The Sub-Primary Range of firing is present in both cat and mouse spinal motoneurones and its relationship to force development is similar for the two species

  Jensen, D. B., Stecina, K., Wienecke, J., Hedegaard, A., Sukiasyan, N., Hultborn, H. & Meehan, C. F., 7 Nov 2018, In: Journal of Neuroscience. 38, 45, p. 9741-9753 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Motor Neurons 100%
  • Cats 87%
  • barbituric acid 44%
  • Temperature 36%
  • Spinal Injections 22%
  5 Citations (Scopus)
• 2017

  Decerebrate mouse model for studies of the spinal cord circuits

  Meehan, C. F., Mayr, K. A., Manuel, M., Nakanishi, S. T. & Whelan, P. J., 1 Apr 2017, In: Nature Protocols. 12, 4, p. 732-747 16 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Cord 100%
  • Spinal Cord 66%
  • Time 29%
  • caN protocol 16%
  • Cerebrum 14%
  15 Citations (Scopus)

• Potassium channel abnormalities are consistent with early axon degeneration of motor axons in the G127X SOD1 mouse model of amyotrophic lateral sclerosis

  Maglemose, R., Hedegaard, A., Lehnhoff, J., Dimintiyanova, K. P., Moldovan, M., Grøndahl, L. & Meehan, C. F., 1 Jun 2017, In: Experimental Neurology. 292, p. 154-167 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Potassium Channels 100%
  • Amyotrophic Lateral Sclerosis 93%
  • Axons 76%
  • Motor Neurons 56%
  • Kv1.2 Potassium Channel 51%
  7 Citations (Scopus)
• 2016

  Nervesystemets udvikling og børns motorik

  Petersen, N. C., Meehan, C. F., Hultborn, H., Petersen, T. H. & Nielsen, J. B., 2016, Fra Tanke til Handling - Bevægelsens Neurobiologi. Christiansen, L., Geertsen, S. S., Lundbye-Jensen, J. & Nielsen, J. B. (eds.). København: Hjerneforum, p. 184-197 14 p.

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education › peer-review
• 2015

  Effect of nitric oxide on spinal evoked potentials and survival rate in rats with decompression sickness

  Randsøe, T., Meehan, C. F., Broholm, H. & Hyldegaard, O., 1 Jan 2015, In: Journal of Applied Physiology. 118, 1, p. 20-8 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Decompression Sickness 100%
  • isosorbide-5-mononitrate 83%
  • Glycerol 71%
  • Evoked Potentials 65%
  • Nitric Oxide 54%
  1 Citation (Scopus)

• Functional plasticity in the respiratory drive to thoracic motoneurons in the segment above a chronic lateral spinal cord lesion

  Ford, T. W., Anissimova, N. P., Meehan, C. F. & Kirkwood, P. A., 21 Oct 2015, In: Journal of Neurophysiology. 115, 1, p. 554-567 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Motor Neurons 100%
  • Spinal Cord 84%
  • Thorax 71%
  • Neurons 54%
  • Normal Distribution 17%
  8 Citations (Scopus)

• Postactivation depression of the Ia EPSP in motoneurons is reduced in both the G127X SOD1 model of amyotrophic lateral sclerosis and in aged mice

  Hedegaard, A., Lehnhoff, J., Moldovan, M., Grøndahl, L., Petersen, N. C. & Meehan, C. F., 18 Jun 2015, In: Journal of Neurophysiology. 114, 2, p. 1196-1210 15 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Excitatory Postsynaptic Potentials 100%
  • Amyotrophic Lateral Sclerosis 92%
  • Motor Neurons 83%
  • Depression 56%
  • Inbred C57BL Mouse 40%
  9 Citations (Scopus)
• 2014

  Abdominal and internal intercostal motoneurones are strong synergists for expiration but are not synergists for Group I monosynaptic afferent inputs

  Ford, T. W., Meehan, C. F. & Kirkwood, P., 2014, Proceedings of The Physiological Society. Vol. 31. p. 1 1 p. PCB066

  Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Communication

  • synergists 100%
  • motor neurons 89%
  • muscles 40%
  • nerve tissue 33%
  • reflexes 15%

• Absence of synergy for monosynaptic Group I inputs between abdominal and internal intercostal motoneurons

  Ford, T. W., Meehan, C. F. & Kirkwood, P. A., 1 Sept 2014, In: Journal of Neurophysiology. 112, 5, p. 1159-68 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Motor Neurons 100%
  • Excitatory Postsynaptic Potentials 80%
  • Intercostal Muscles 33%
  • Abdominal Muscles 28%
  • Muscles 20%
  5 Citations (Scopus)

• In vivo intracellular recordings from spinal lumbar motoneurones in P0-deficient mice indicate an activity-dependent axonal conduction failure in otherwise functional motoneurones

  Lehnhoff, J., Moldovan, M., Hedegaard, A., Grøndahl, L. & Meehan, C. F., 2014, Proceedings of The Physiological Society. UK, Vol. 31. PCA079

  Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research

  • Motor Neurons 100%
  • Anesthesia 54%
  • Action Potentials 46%
  • Charcot-Marie-Tooth Disease 46%
  • Carisoprodol 37%

• Post activation depression of the Ia EPSP in motoneurones is reduced in both aged mice and in the G127X SOD1 model of Amyotrophic lateral sclerosis

  Hedegaard, A., Lehnhoff, J., Moldovan, M., Grøndahl, L. & Meehan, C. F., 2014, Proceedings of The Physiological Society. Physiology 2014 (London, UK) (2014), Vol. 31. PCA070

  Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research

  • amyotrophic lateral sclerosis 100%
  • motor neurons 73%
  • mice 36%
  • anesthesia 6%
  • cells 5%
• 2013

  Control and role of plateau potential properties in the spinal cord

  Hultborn, H., Zhang, M. & Meehan, C. F., 2013, In: Current Pharmaceutical Design. 19, 24, p. 4357-4370 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Cord 100%
  • Plastic Property 94%
  • Motor Neurons 78%
  • Spinal Cord 66%
  • Central Pattern Generators 29%
  15 Citations (Scopus)

• Rhythmic activity of feline dorsal and ventral spinocerebellar tract neurons during fictive motor actions

  Fedirchuk, B., Stecina, K., Kristensen, K. K., Zhang, M., Meehan, C. F., Bennett, D. J. & Hultborn, H., 15 Jan 2013, In: Journal of Neurophysiology. 109, 2, p. 375-88 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Spinocerebellar Tracts 100%
  • Felidae 68%
  • Neurons 37%
  • Locomotion 19%
  • Hindlimb 16%
  24 Citations (Scopus)
• 2012

  Fictive locomotion in the adult decerebrate and spinal mouse in vivo

  Meehan, C. F., Grøndahl, L., Nielsen, J. B. & Hultborn, H. R., Jan 2012, In: Journal of Physiology. 590, 2, p. 289-300 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Central Pattern Generators 100%
  • Locomotion 65%
  • Transgenic Mice 40%
  • Nialamide 37%
  • 5-Hydroxytryptophan 30%
  26 Citations (Scopus)
• 2011

  Dendrite-derived supernumerary axons on adult axotomized motor neurons possess proteins that are essential for the initiation and propagation of action potentials and synaptic vesicle release

  Meehan, C. F., MacDermid, V. E., Montague, S. J., Neuber-Hess, M. & Rose, P. K., 4 May 2011, In: Journal of Neuroscience. 31, 18, p. 6732-40 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Synaptic Vesicles 100%
  • Dendrites 88%
  • Motor Neurons 83%
  • Action Potentials 77%
  • Axons 75%
  7 Citations (Scopus)

• Electrophysiological and morphological characterization of propriospinal interneurons in the thoracic spinal cord

  Saywell, S. A., Ford, T. W., Meehan, C. F., Todd, A. J. & Kirkwood, P. A., Feb 2011, In: Journal of Neurology & Neurophysiology. 105, 2, p. 806-26 21 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Interneurons 100%
  • Axons 82%
  • Spinal Cord 77%
  • Thorax 65%
  • neurobiotin 25%
  46 Citations (Scopus)

• Reciprocal Ia inhibition contributes to motoneuronal hyperpolarisation during the inactive phase of locomotion and scratching in the cat

  Geertsen, S. S., Stecina, K., Meehan, C. F., Nielsen, J. B. & Hultborn, H., Jan 2011, In: Journal of Physiology. 589, 1, p. 119-134 16 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Locomotion 100%
  • Motor Neurons 99%
  • Cats 87%
  • Psychological Inhibition 84%
  • Renshaw Cells 68%
  50 Citations (Scopus)
• 2010

  Ia inhibitory neurons are involved in the hyperpolarization of motoneurones during their inactive phases in locomotion and scratching in the cat

  Geertsen, S. S., Stecina, K., Meehan, C. F., Nielsen, J. B. & Hultborn, H., 2010.

  Research output: Contribution to conference › Paper › Research › peer-review

• Intrinsic properties of lumbar motor neurones in the adult G127insTGGG superoxide dismutase-1 mutant mouse in vivo: evidence for increased persistent inward currents

  Meehan, C. F., Moldovan, M., Marklund, S. L., Graffmo, K. S., Nielsen, J. B. & Hultborn, H., Dec 2010, In: Acta Physiologica (Print Edition). 200, 4, p. 361-376 16 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Superoxide Dismutase-1 100%
  • Motor Neurons 76%
  • Amyotrophic Lateral Sclerosis 42%
  • Membrane Potentials 38%
  • Neurodegenerative Diseases 11%
  47 Citations (Scopus)

• Intrinsic properties of mouse lumbar motoneurons revealed by intracellular recording in vivo

  Meehan, C. F., Sukiasyan, N., Zhang, M., Nielsen, J. B. & Hultborn, H., May 2010, In: Journal of Neurophysiology. 103, 5, p. 2599-2610 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Motor Neurons 100%
  • Hypnorm 51%
  • Cats 43%
  • Synaptic Potentials 32%
  • Midazolam 29%
  42 Citations (Scopus)
• 2009

  Gener og bevægelse

  Hultborn, H. & Meehan, C. F., 2009, Hjernen i bevægelse. Bøgeskov, J., Ellemann, K. & Nielsen, J. B. (eds.). 1 ed. Hjerneforum, p. 9-21 12 p.

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
• 2007

  Axonal regeneration and development of de novo axons from distal dendrites of adult feline commissural interneurons after a proximal axotomy

  Fenrich, K. K., Skelton, N., MacDermid, V. E., Meehan, C. F., Armstrong, S., Neuber-Hess, M. S. & Rose, P. K., 2007, In: Journal of Comparative Neurology. 502, 6, p. 1079-97 19 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Commissural Interneurons 100%
  • Axotomy 73%
  • Felidae 62%
  • Dendrites 56%
  • Axons 48%
  39 Citations (Scopus)

• The respiratory drive to thoracic motoneurones in the cat and its relation to the connections from expiratory bulbospinal neurones

  Saywell, S. A., Anissimova, N. P., Ford, T. W., Meehan, C. F. & Kirkwood, P. A., 2007, In: Journal of Physiology. 579, Pt 3, p. 765-82 18 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Motor Neurons 100%
  • Cats 87%
  • Thorax 71%
  • Neurons 63%
  • Excitatory Postsynaptic Potentials 36%
  24 Citations (Scopus)
• 2004

  Rostrocaudal distribution of motoneurones and variation in ventral horn area within a segment of the feline thoracic spinal cord

  Meehan, C. F., Ford, T. W., Road, J. D., Donga, R., Saywell, S. A., Anissimova, N. P. & Kirkwood, P. A., 2004, In: Journal of Comparative Neurology. 472, 3, p. 281-91 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Horns 100%
  • Felidae 95%
  • Motor Neurons 80%
  • Spinal Cord 68%
  • Thorax 57%
  12 Citations (Scopus)