Børge Nordestgaard

Research output

Research output per year 1998 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019

• 576 Journal article
• 17 Comment/debate
• 15 Review
• 9 Letter
• 28 More
  • 8 Conference abstract for conference
  • 7 Conference abstract in journal
  • 7 Editorial
  • 5 Book chapter
  • 1 Book

Research output per year

Research output per year

Search results

• 2017

  Rare variant analysis of human and rodent obesity genes in individuals with severe childhood obesity

  Hendricks, A. E., Bochukova, E. G., Marenne, G., Keogh, J. M., Atanassova, N., Bounds, R., Wheeler, E., Mistry, V., Henning, E., Understanding Society Scientific Group, Körner, A., Muddyman, D., McCarthy, S., Hinney, A., Hebebrand, J., Scott, R. A., Langenberg, C., Wareham, N. J., Surendran, P., Howson, J. M., & 18 othersButterworth, A. S., Danesh, J., EPIC-CVD Consortium, Nordestgaard, B., Nielsen, S. F., Afzal, S., Papadia, S., Ashford, S., Garg, S., Millhauser, G. L., Palomino, R. I., Kwasniewska, A., Tachmazidou, I., O'Rahilly, S., Zeggini, E., UK10K Consortium, Barroso, I. & Farooqi, I. S., 2017, In: Scientific Reports. 7, 14 p., 4394.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Morbid Obesity 100%
  • Pediatric Obesity 93%
  • Rodentia 71%
  • Obesity 60%
  • Genes 34%
  25 Citations (Scopus)

  80 Downloads (Pure)

• Remnant Cholesterol Elicits Arterial Wall Inflammation and a Multilevel Cellular Immune Response in Humans

  Bernelot Moens, S. J., Verweij, S. L., Schnitzler, J. G., Stiekema, L. C. A., Bos, M., Langsted, A., Kuijk, C., Bekkering, S., Voermans, C., Verberne, H. J., Nordestgaard, B. G., Stroes, E. S. G. & Kroon, J., 1 May 2017, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 37, 5, p. 969-975

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Hyperlipoproteinemia Type III 100%
  • Arteritis 81%
  • Cellular Immunity 59%
  • Cholesterol 45%
  • Monocytes 36%
  29 Citations (Scopus)

• Remnant lipoproteins

  Varbo, A. & Nordestgaard, B. G., 2017, In: Current Opinion in Lipidology. 28, 4, p. 300-307

  Research output: Contribution to journal › Review › peer-review

  • Lipoproteins 100%
  • Cardiovascular Diseases 76%
  • Cholesterol 64%
  • lipoprotein cholesterol 22%
  • Risk Reduction Behavior 17%
  34 Citations (Scopus)

• Reply to: “Appropriate use of cholesterol-lowering therapy”

  Langsted, A., Freiberg, J. J. & Nordestgaard, B. G., Jul 2017, In: Atherosclerosis. 262, p. 200-201 2 p.

  Research output: Contribution to journal › Comment/debate › Research

• Risk Factors for Chronic Cough Among 14,669 Individuals From the General Population

  Çolak, Y., Nordestgaard, B. G., Laursen, L. C., Afzal, S., Lange, P. & Dahl, M., Sept 2017, In: Chest. 152, 3, p. 563-573 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Cough 100%
  • Smokers 88%
  • Population 40%
  • Asthma 36%
  • Bronchiectasis 27%
  35 Citations (Scopus)

• Shorter leukocyte telomere length is associated with higher risk of infections: a prospective study of 75,309 individuals from the general population

  Helby, J., Nordestgaard, B. G., Benfield, T. & Bojesen, S. E., 31 Jul 2017, In: Haematologica. 102, 8, p. 1457-1465 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Telomere 100%
  • Leukocytes 71%
  • Prospective Studies 57%
  • Infections 43%
  • Population 35%
  35 Citations (Scopus)

  41 Downloads (Pure)

• SNP interaction pattern identifier (SIPI): An intensive search for SNP-SNP interaction patterns

  Lin, H. Y., Chen, D. T., Huang, P. Y., Liu, Y. H., Ochoa, A., Zabaleta, J., Mercante, D. E., Fang, Z., Sellers, T. A., Pow-Sang, J. M., Cheng, C. H., Eeles, R., Easton, D., Kote-Jarai, Z., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G. G., Wiklund, F., Gronberg, H., & 22 othersHaiman, C. A., Schleutker, J., Nordestgaard, B. G., Travis, R. C., Hamdy, F., Pashayan, N., Khaw, K. T., Stanford, J. L., Blot, W. J., Thibodeau, S. N., Maier, C., Kibel, A. S., Cybulski, C., Cannon-Albright, L., Brenner, H., Kaneva, R., Batra, J., Teixeira, M. R., Pandha, H., Lu, Y. J., The Practical Consortium & Park, J. Y., 2017, In: Bioinformatics. 33, 6, p. 822-833 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Single Nucleotide Polymorphism 100%
  • Interaction 85%
  • Additive 79%
  • Simulation 74%
  • Dimensionality reduction 64%
  5 Citations (Scopus)

• Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

  Webb, T. R., Erdmann, J., Stirrups, K. E., Stitziel, N. O., Masca, N. G. D., Jansen, H., Kanoni, S., Nelson, C. P., Ferrario, P. G., König, I. R., Eicher, J. D., Johnson, A. D., Hamby, S. E., Betsholtz, C., Ruusalepp, A., Franzén, O., Schadt, E., Auer, P. L., Björkegren, J. L. M., Weeke, P. E., & 31 othersSchick, U. M., Lu, Y., Zhang, H., Dubé, M-P., Goel, A., Farrall, M., Peloso, G. M., Won, H-H., Do, R., van Iperen, E. P. A., Kruppa, J., Mahajan, A., Scott, R. A., Willenborg, C., Braund, P. S., van Capelleveen, J. C., Doney, A. S. F., Donnelly, L. A., Asselta, R., Angelica Merlini, P., Duga, S., Marziliano, N., Denny, J. C., Shaffer, C. M., El Mokhtari, N. E., Franke, A., Heilmann-Heimbach, S., Hengstenberg, C., Hoffmann, P., Nordestgaard, B. G. & Wellcome Trust Case Control Consortium, 21 Feb 2017, In: Journal of the American College of Cardiology. 69, 7, p. 823-836 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Coronary Artery Disease 100%
  • Genome-Wide Association Study 25%
  • Gene Frequency 23%
  • Single Nucleotide Polymorphism 20%
  • Genome 16%
  114 Citations (Scopus)

  97 Downloads (Pure)

• Telomere length and depression: prospective cohort study and Mendelian randomisation study in 67 306 individuals

  Wium-Andersen, M. K., Ørsted, D. D., Rode, L., Bojesen, S. E. & Nordestgaard, B. G., Jan 2017, In: The British journal of psychiatry : the journal of mental science. 210, 1, p. 31-38 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Telomere 100%
  • Random Allocation 89%
  • Cohort Studies 62%
  • Prospective Studies 57%
  • Antidepressive Agents 35%
  15 Citations (Scopus)

• The R213G polymorphism in SOD3 protects against allergic airway inflammation

  Gaurav, R., Varasteh, J. T., Weaver, M. R., Jacobson, S. R., Hernandez-Lagunas, L., Liu, Q., Nozik-Grayck, E., Chu, H. W., Alam, R., Nordestgaard, B. G., Kobylecki, C. J., Afzal, S., Chupp, G. L. & Bowler, R. P., 7 Sept 2017, In: JCI insight. 2, 17, 15 p., e95072.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Interleukin-33 100%
  • Single Nucleotide Polymorphism 61%
  • Asthma 56%
  • ethylpyridinium 49%
  • Inflammation 43%
  12 Citations (Scopus)

• TP53 Arg72Pro, mortality after cancer, and all-cause mortality in 105,200 individuals

  Kodal, J. B., Vedel-Krogh, S., Kobylecki, C. J., Nordestgaard, B. G. & Bojesen, S. E., 1 Dec 2017, In: Scientific Reports. 7, 8 p., 336.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Mortality 100%
  • Neoplasms 64%
  • Genotype 47%
  • Population 19%
  • Incidence 16%
  5 Citations (Scopus)

  59 Downloads (Pure)

• Use of Repeated Blood Pressure and Cholesterol Measurements to Improve Cardiovascular Disease Risk Prediction: An Individual-Participant-Data Meta-Analysis

  Paige, E., Barrett, J., Pennells, L., Sweeting, M., Willeit, P., Di Angelantonio, E., Gudnason, V., Nordestgaard, B. G., Psaty, B. M., Goldbourt, U., Best, L. G., Assmann, G., Salonen, J. T., Nietert, P. J., Verschuren, W. M. M., Brunner, E. J., Kronmal, R. A., Salomaa, V., Bakker, S. J. L., Dagenais, G. R., & 27 othersSato, S., Jansson, J-H., Willeit, J., Onat, A., de la Cámara, A. G., Roussel, R., Völzke, H., Dankner, R., Tipping, R. W., Meade, T. W., Donfrancesco, C., Kuller, L. H., Peters, A., Gallacher, J., Kromhout, D., Iso, H., Knuiman, M., Casiglia, E., Kavousi, M., Palmieri, L., Sundström, J., Davis, B. R., Njølstad, I., Couper, D., Danesh, J., Thompson, S. G. & Wood, A., 15 Oct 2017, In: American Journal of Epidemiology. 186, 8, p. 899-907 9 p.

  Research output: Contribution to journal › Review › peer-review

  • Data Analysis 100%
  • Meta-Analysis 99%
  • Cholesterol 98%
  • Cardiovascular Diseases 96%
  • Blood Pressure 85%
  16 Citations (Scopus)

  58 Downloads (Pure)

• Using genetics to explore whether the cholesterol-lowering drug ezetimibe may cause an increased risk of cancer

  Kobberø Lauridsen, B., Stender, S., Frikke-Schmidt, R., Nordestgaard, B. G. & Tybjærg-Hansen, A., 1 Dec 2017, In: International Journal of Epidemiology. 46, 6, p. 1777-1785

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Ezetimibe 100%
  • Cholesterol 53%
  • Pharmaceutical Preparations 30%
  • Alleles 24%
  • Neoplasms 23%
  2 Citations (Scopus)

• Vitamin D, Hypertension, and Ischemic Stroke in 116 655 Individuals From the General Population: A Genetic Study

  Afzal, S. & Nordestgaard, B. G., 1 Sept 2017, In: Hypertension. 70, 3, p. 499-507

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Population Genetics 100%
  • Vitamin D 76%
  • Stroke 55%
  • Hypertension 53%
  • Confidence Intervals 48%
  21 Citations (Scopus)

• Vitamin D and Risk of Cardiovascular Disease

  Afzal, S. & Nordestgaard, B. G., 2017, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 37, 11, p. 1981-1982

  Research output: Contribution to journal › Editorial

  1 Citation (Scopus)

• Volume and dimensions of angiographically normal coronary arteries assessed by multidetector computed tomography

  Sørensen, S. K., Kühl, J. T., Fuchs, A., Norsk, J. B., Køber, L. V., Nordestgaard, B. G. & Kofoed, K. F., Jul 2017, In: Journal of Cardiovascular Computed Tomography. 11, 4, p. 295-301

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Multidetector Computed Tomography 100%
  • Coronary Vessels 68%
  • Nitroglycerin 42%
  • Arteries 20%
  • Reference Values 14%
  4 Citations (Scopus)

• Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits

  Tachmazidou, I., Süveges, D., Min, J. L., Ritchie, G. R. S., Steinberg, J., Walter, K., Iotchkova, V., Schwartzentruber, J., Huang, J., Memari, Y., McCarthy, S., Crawford, A. J., Bombieri, C., Cocca, M., Farmaki, A-E., Gaunt, T. R., Jousilahti, P., Kooijman, M. N., Lehne, B., Malerba, G., & 31 othersMännistö, S., Matchan, A., Medina-Gomez, C., Metrustry, S. J., Nag, A., Ntalla, I., Paternoster, L., Rayner, N. W., Sala, C., Scott, W. R., Shihab, H. A., Southam, L., St Pourcain, B., Traglia, M., Trajanoska, K., Zaza, G., Zhang, W., Artigas, M. S., Bansal, N., Benn, M., Chen, Z., Danecek, P., Lin, W-Y., Locke, A. E., Luan, J., Manning, A. K., Mulas, A., Sidore, C., Tybjaerg-Hansen, A., Nordestgaard, B. G. & SpiroMeta Consortium, 1 Jun 2017, In: American Journal of Human Genetics. 100, 6, p. 865-884 20 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Whole Genome Sequencing 100%
  • Body Fat Distribution 57%
  • Multifactorial Inheritance 53%
  • Chromosome Mapping 52%
  • Genome-Wide Association Study 44%
  47 Citations (Scopus)

  60 Downloads (Pure)
• 2016

  Alcohol consumption and risk of atrial fibrillation: Observational and genetic estimates of association

  Tolstrup, J. S., Wium-Andersen, M. K., Ørsted, D. D. & Nordestgaard, B. G., 1 Sept 2016, In: European Journal of Preventive Cardiology. 23, 14, p. 1514-23 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Alcohol Drinking 100%
  • Atrial Fibrillation 97%
  • Alcohols 44%
  • Confidence Intervals 11%
  • Genetic Variation 9%
  14 Citations (Scopus)

• An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression

  Wyszynski, A., Hong, C., Lam, K., Michailidou, K., Lytle, C., Yao, S., Zhang, Y., Bolla, M. K., Wang, Q., Dennis, J., Hopper, J. L., Southey, M. C., Schmidt, M. K., Broeks, A., Muir, K., Lophatananon, A., Fasching, P. A., Beckmann, M. W., Peto, J., dos Santos Silva, I., & 90 othersSawyer, E. J., Tomlinson, I., Burwinkel, B., Marme, F., Guénel, P., Truong, T., Bojesen, S. E., Nordestgaard, B. G., González-Neira, A., Benitez, J., Neuhausen, S. L., Brenner, H., Dieffenbach, A. K., Meindl, A., Schmutzler, R. K., Brauch, H., Nevanlinna, H., Khan, S., Matsuo, K., Ito, H., Doerk, T., Bogdanova, N. V., Lindblom, A., Margolin, S., Mannermaa, A., Kosma, V-M., Wu, A. H., Van Den Berg, D., Lambrechts, D., Wildiers, H., Chang-Claude, J., Rudolph, A., Radice, P., Peterlongo, P., Couch, F. J., Olson, J. E., Giles, G., Milne, R. L., Haiman, C. A., Henderson, B. E., Dumont, M., Teo, S-H., Wong, T. Y., Kristensen, V., Zheng, W., Long, J., Winqvist, R., Pylkäs, K., Andrulis, I. L., Knight, J. A., Devilee, P., Seynaeve, C., García-Closas, M., Figueroa, J., Klevebring, D., Czene, K., Hooning, M. J., van den Ouweland, A. M. W., Darabi, H., Shu, X-O., Gao, Y-T., Cox, A., Blot, W., Signorello, L. B., Shah, M., Kang, D., Choi, J-Y., Hartman, M., Miao, H., Hamann, U., Jakubowska, A., Lubinski, J., Sangrajrang, S., McKay, J., Toland, A. E., Yannoukakos, D., Shen, C-Y., Wu, P-E., Swerdlow, A., Orr, N., Simard, J., Pharoah, P. P. D., Dunning, A. M., Chenevix-Trench, G., Hall, P., Bandera, E. V., Amos, C., Ambrosone, C. B., Easton, D. F. & Cole, M. D., 1 Sept 2016, In: Human Molecular Genetics. 25, 17, p. 3863-3876 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Breast Neoplasms 100%
  • Genotype 37%
  • Genome-Wide Association Study 27%
  • Chromatin 23%
  • Estrogens 21%
  18 Citations (Scopus)

• Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: Genetic variants as instruments for circulating levels

  Bonilla, C., Lewis, S. J., Rowlands, M-A., Gaunt, T. R., Davey-Smith, G., Gunnell, D., Palmer, T. M., Donovan, J. L., Hamdy, F. C., Neal, D. E., Eeles, R., Easton, D., Kote-Jarai, Z., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G., Wiklund, F., Grönberg, H., Haiman, C. A., & 22 othersSchleutker, J., Nordestgaard, B. G., Travis, R. C., Pashayan, N., Khaw, K-T., Stanford, J. L., Blot, W. J., Thibodeau, S. N., Maier, C., Kibel, A. S., Cybulski, C., Cannon-Albright, L., Brenner, H., Park, J-S., Kaneva, R., Batra, J., Teixeira, M. R., Pandha, H., PRACTICAL consortium, Lathrop, M., Martin, R. M. & Holly, J. M. P., 1 Oct 2016, In: International Journal of Cancer. 139, 7, p. 1520-1533 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • insulin 100%
  • Insulin-Like Growth Factor Binding Proteins 91%
  • Insulin-Like Growth Factor II 87%
  • Somatomedins 74%
  • Random Allocation 68%
  10 Citations (Scopus)

  141 Downloads (Pure)

• Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

  Gusev, A., Shi, H., Kichaev, G., Pomerantz, M., Li, F., Long, H. W., Ingles, S. A., Kittles, R. A., Strom, S. S., Rybicki, B. A., Nemesure, B., Isaacs, W. B., Zheng, W., Pettaway, C. A., Yeboah, E. D., Tettey, Y., Biritwum, R. B., Adjei, A. A., Tay, E., Truelove, A., & 31 othersNiwa, S., Chokkalingam, A. P., John, E. M., Murphy, A. B., Signorello, L. B., Carpten, J., Leske, M. C., Wu, S-Y., Hennis, A. J. M., Neslund-Dudas, C., Hsing, A. W., Chu, L., Goodman, P. J., Klein, E. A., Witte, J. S., Casey, G., Kaggwa, S., Cook, M. B., Stram, D. O., Blot, W. J., Eeles, R. A., Easton, D., Kote-Jarai, Z., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G., Southey, M. C., Fitzgerald, L. M., Nordestgaard, B. G. & PRACTICAL consortium, 7 Apr 2016, In: Nature Communications. 7, p. 1-13 13 p., 10979.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Atlases 100%
  • Acetylation 94%
  • African Americans 87%
  • cancer 87%
  • Prostatic Neoplasms 73%
  30 Citations (Scopus)

• Blood Eosinophils and Exacerbations in Chronic Obstructive Pulmonary Disease: The Copenhagen General Population Study

  Vedel-Krogh, S., Nielsen, S. F., Lange, P., Vestbo, J. & Nordestgaard, B. G., 1 May 2016, In: American Journal of Respiratory and Critical Care Medicine. 193, 9, p. 965-974

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Eosinophils 100%
  • Chronic Obstructive Pulmonary Disease 91%
  • Population 40%
  • Disease Progression 30%
  • Spirometry 10%
  196 Citations (Scopus)

• Blood lipids and prostate cancer: a Mendelian randomization analysis

  Bull, C. J., Bonilla, C., Holly, J. M. P., Perks, C. M., Davies, N., Haycock, P., Yu, O. H. Y., Richards, J. B., Eeles, R., Easton, D., Kote-Jarai, Z., Amin Al Olama, A., Benlloch, S., Muir, K., Giles, G. G., MacInnis, R. J., Wiklund, F., Gronberg, H., Haiman, C. A., Schleutker, J., & 23 othersNordestgaard, B. G., Travis, R. C., Neal, D., Pashayan, N., Khaw, K-T., Stanford, J. L., Blot, W. J., Thibodeau, S., Maier, C., Kibel, A. S., Cybulski, C., Cannon-Albright, L., Brenner, H., Park, J., Kaneva, R., Batra, J., Teixeira, M. R., Micheal, A., Pandha, H., Smith, G. D., Lewis, S. J., Martin, R. M. & PRACTICAL consortium, 1 Jun 2016, In: Cancer Medicine. 5, 6, p. 1125-1136 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Mendelian Randomization Analysis 100%
  • Prostatic Neoplasms 49%
  • Lipids 40%
  • LDL Lipoproteins 31%
  • Hydroxymethylglutaryl CoA Reductases 21%
  34 Citations (Scopus)

• Body Mass Index and All-Cause Mortality-Reply

  Afzal, S. & Nordestgaard, B. G., 6 Sept 2016, In: JAMA. 316, 9, 992.

  Research output: Contribution to journal › Comment/debate › Research

  1 Citation (Scopus)

• Change in Body Mass Index Associated With Lowest Mortality in Denmark, 1976-2013

  Afzal, S., Tybjærg-Hansen, A., Jensen, G. B. & Nordestgaard, B. G., 10 May 2016, In: J A M A: The Journal of the American Medical Association. 315, 18, p. 1989-96 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Denmark 100%
  • Body Mass Index 67%
  • Mortality 47%
  • Emigration and Immigration 6%
  • Population 6%
  86 Citations (Scopus)

• Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

  Stitziel, N. O., Stirrups, K. E., Masca, N. G. D., Erdmann, J., Ferrario, P. G., König, I. R., Weeke, P. E., Webb, T. R., Auer, P. L., Schick, U. M., Lu, Y., Zhang, H., Dubé, M-P., Goel, A., Farrall, M., Peloso, G. M., Won, H-H., Do, R., van Iperen, E. P. A., Kanoni, S., & 31 othersKruppa, J., Mahajan, A., Scott, R. A., Willenberg, C., Braund, P. S., van Capelleveen, J. C., Doney, A. S. F., Donnelly, L. A., Asselta, R., Merlini, P. A., Duga, S., Marziliano, N., Denny, J. C., Shaffer, C. M., El Mokhtari, N. E., Franke, A., Gottesman, O., Heilmann-Heimbach, S., Hengstenberg, C., Hoffman, P., Holmen, O. L., Hveem, K., Jansson, J-H., Jöckel, K-H., Kessler, T., Kriebel, J., Laugwitz, K-L., Marouli, E., Martinelli, N., Nordestgaard, B. G. & Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators, 24 Mar 2016, In: New England Journal of Medicine. 374, 12, p. 1134-1144 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Coronary Disease 100%
  • Coronary Artery Disease 93%
  • Gene Frequency 55%
  • Loss of Function Mutation 47%
  • Odds Ratio 45%
  264 Citations (Scopus)

• Coffee intake, cardiovascular disease and allcause mortality: Observational and mendelian randomization analyses in 95 000-223 000 individuals

  Nordestgaard, A. T. & Nordestgaard, B. G., 2016, In: International Journal of Epidemiology. 45, 6, p. 1938-1952 15 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Mendelian Randomization Analysis 100%
  • Coffee 73%
  • Cardiovascular Diseases 44%
  • Caffeine 36%
  • Mortality 31%
  31 Citations (Scopus)

• Commentary: Nonfasting remnant cholesterol simplifies triglyceride-rich lipoproteins for clinical use, and metabolomic phenotyping ignites scientific curiosity

  Varbo, A., Langsted, A. & Nordestgaard, B. G., Oct 2016, In: International Journal of Epidemiology. 45, 5, p. 1379-1385 7 p.

  Research output: Contribution to journal › Comment/debate › Research

  2 Citations (Scopus)

• Complement C3 and High Risk of Venous Thromboembolism: 80517 Individuals from the Copenhagen General Population Study

  Nørgaard, I., Nielsen, S. F. & Nordestgaard, B. G., Mar 2016, In: Clinical Chemistry. 62, 3, p. 525-534 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Complement C3 100%
  • Venous Thromboembolism 86%
  • Population 31%
  • Pulmonary Embolism 17%
  • Venous Thrombosis 17%
  17 Citations (Scopus)

• Components of the Metabolic Syndrome and Risk of Type 2 Diabetes

  Marott, S. C. W., Nordestgaard, B. G., Tybjærg-Hansen, A. & Benn, M., Aug 2016, In: The Journal of clinical endocrinology and metabolism. 101, 8, p. 3212-3221 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Metabolic Syndrome 100%
  • Blood Pressure 91%
  • Metabolic 88%
  • Type 2 Diabetes Mellitus 81%
  • Glucose 80%
  27 Citations (Scopus)

• Copenhagen comorbidity in HIV infection (COCOMO) study: a study protocol for a longitudinal, non-interventional assessment of non-AIDS comorbidity in HIV infection in Denmark

  Ronit, A., Haissman, J. M., Kirkegaard-Klitbo, D. M., Kristensen, T. S., Lebech, A-M., Benfield, T., Gerstoft, J., Ullum, H., Køber, L., Kjær, A., Kofoed, K., Vestbo, J., Nordestgaard, B. G., Lundgren, J. & Nielsen, S. D., 26 Nov 2016, In: BMC Infectious Diseases. 16, 9 p., 713.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Denmark 100%
  • HIV Infections 83%
  • Comorbidity 73%
  • HIV 64%
  • Cohort Studies 24%
  28 Citations (Scopus)

  130 Downloads (Pure)

• Data on plasma levels of apolipoprotein E, correlations with lipids and lipoproteins stratified by APOE genotype, and risk of ischemic heart disease

  Rasmussen, K. L., Tybjærg-Hansen, A., Nordestgaard, B. G. & Frikke-Schmidt, R., 1 Mar 2016, In: Data in Brief. 6, p. 923-932 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Apolipoproteins E 100%
  • Lipoproteins 89%
  • Myocardial Ischemia 83%
  • Genotype 67%
  • Lipids 61%
  7 Citations (Scopus)

  89 Downloads (Pure)

• Does SOD3 R213G Homozygosity Influence Morbidity, Mortality, and Lung Function in the General Population?

  Kobylecki, C. J., Afzal, S. & Nordestgaard, B. G., 20 May 2016, In: Antioxidants & Redox Signaling. 24, 15, p. 884-891 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Homozygote 100%
  • Forced Expiratory Volume 64%
  • Chronic Obstructive Pulmonary Disease 53%
  • Morbidity 53%
  • Myocardial Ischemia 53%
  4 Citations (Scopus)

• Elevated C-reactive protein and late-onset bipolar disorder in 78 809 individuals from the general population

  Wium-Andersen, M. K., Ørsted, D. D. & Nordestgaard, B. G., Feb 2016, In: British Journal of Psychiatry. 208, 2, p. 138-45 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Late Onset Disorders 100%
  • Bipolar Disorder 72%
  • C-Reactive Protein 65%
  • Population 29%
  • Odds Ratio 13%
  28 Citations (Scopus)

• Elevated Lipoprotein(a) Levels, LPA Risk Genotypes, and Increased Risk of Heart Failure in the General Population

  Kamstrup, P. R. & Nordestgaard, B. G., 1 Jan 2016, In: JACC. Heart failure. 4, 1, p. 78-87 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Lipoprotein(a) 100%
  • Heart Failure 59%
  • Genotype 58%
  • Aortic Valve Stenosis 39%
  • Population 31%
  46 Citations (Scopus)

• Estimating the Population Impact of Lp(a) Lowering on the Incidence of Myocardial Infarction and Aortic Stenosis: Brief Report

  Afshar, M., Kamstrup, P. R., Williams, K., Sniderman, A. D., Nordestgaard, B. G. & Thanassoulis, G., 1 Dec 2016, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 36, 12, p. 2421-2423 3 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Aortic Valve Stenosis 100%
  • Myocardial Infarction 65%
  • Incidence 44%
  • Population 35%
  • Confidence Intervals 20%
  17 Citations (Scopus)

• Fasting is not routinely required for determination of a lipid profile: clinical and laboratory implications including flagging at desirable concentration cut-points—a joint consensus statement from the European Atherosclerosis Society and European Federation of Clinical Chemistry and Laboratory Medicine

  Nordestgaard, B. G., Langsted, A., Mora, S., Kolovou, G., Baum, H., Bruckert, E., Watts, G. F., Sypniewska, G., Wiklund, O., Borén, J., Chapman, M. J., Cobbaert, C. M., Descamps, O. S., von Eckardstein, A., Kamstrup, P. R., Pulkki, K., Kronenberg, F., Remaley, A. T., Rifai, N., Ros, E., & 1 othersLanglois, M., 1 Jul 2016, In: European Heart Journal. 37, 25, p. 1944-1958

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Clinical Chemistry 100%
  • Consensus 73%
  • Atherosclerosis 62%
  • Fasting 61%
  • Medicine 56%
  275 Citations (Scopus)

• Fasting Is Not Routinely Required for Determination of a Lipid Profile: Clinical and Laboratory Implications Including Flagging at Desirable Concentration Cutpoints-A Joint Consensus Statement from the European Atherosclerosis Society and European Federation of Clinical Chemistry and Laboratory Medicine

  Nordestgaard, B. G., Langsted, A., Mora, S., Kolovou, G., Baum, H., Bruckert, E., Watts, G. F., Sypniewska, G., Wiklund, O., Borén, J., Chapman, M. J., Cobbaert, C., Descamps, O. S., von Eckardstein, A., Kamstrup, P. R., Pulkki, K., Kronenberg, F., Remaley, A. T., Rifai, N., Ros, E., & 1 othersLanglois, M., Jul 2016, In: Clinical Chemistry. 62, 7, p. 930-946 17 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Clinical Chemistry 100%
  • Consensus 73%
  • Atherosclerosis 62%
  • Fasting 61%
  • Medicine 56%
  98 Citations (Scopus)

• Fedme øger risikoen for hjerte-kar-sygdom

  Translated title of the contribution: Obesity increases the risk of cardiovascular diseaseAfzal, S. & Nordestgaard, B. G., 31 Oct 2016, In: Ugeskrift for Laeger. 178, p. 1-5 6 p., V06160404.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Cardiovascular Diseases 100%
  • Obesity 96%
  • Primary Prevention 35%
  • Random Allocation 33%
  • Weight Loss 28%

• Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies

  Joshi, A. D., Andersson, C., Buch, S., Stender, S., Noordam, R., Weng, L-C., Weeke, P. E., Auer, P. L., Boehm, B., Chen, C., Choi, H., Curhan, G., Denny, J. C., De Vivo, I., Eicher, J. D., Ellinghaus, D., Folsom, A. R., Fuchs, C., Gala, M., Haessler, J., & 35 othersHofman, A., Hu, F., Hunter, D. J., Janssen, H. L. A., Kang, J. H., Kooperberg, C., Kraft, P., Kratzer, W., Lieb, W., Lutsey, P. L., Darwish Murad, S., Nordestgaard, B. G., Pasquale, L. R., Reiner, A. P., Ridker, P. M., Rimm, E., Rose, L. M., Shaffer, C. M., Schafmayer, C., Tamimi, R. M., Uitterlinden, A. G., Völker, U., Völzke, H., Wakabayashi, Y., Wiggs, J. L., Zhu, J., Roden, D. M., Stricker, B. H. C., Tang, W., Teumer, A., Hampe, J., Tybjærg-Hansen, A., Chasman, D. I., Chan, A. T. & Johnson, A. D., 1 Aug 2016, In: Gastroenterology. 151, 2, 351 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Gallstones 100%
  • Genome-Wide Association Study 93%
  • Meta-Analysis 66%
  • Odds Ratio 57%
  • Bile Acids and Salts 39%
  40 Citations (Scopus)

• Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array

  Saunders, E. J., Dadaev, T., Leongamornlert, D. A., Al Olama, A. A., Benlloch, S., Giles, G. G., Wiklund, F., Gronberg, H., Haiman, C. A., Schleutker, J., Nordestgaard, B., Travis, R. C., Neal, D., Pasayan, N., Khaw, K-T., Stanford, J. L., Blot, W. J., Thibodeau, S. N., Maier, C., Kibel, A. S., & 14 othersCybulski, C., Cannon-Albright, L., Brenner, H., Park, J. Y., Kaneva, R., Batra, J., Teixeira, M. R., Pandha, H., Govindasami, K., Muir, K., Easton, D. F., Eeles, R. A., Kote-Jarai, Z. & UK Genetic Prostate Cancer Study Collaborators, 12 Apr 2016, In: British Journal of Cancer. 114, p. 945-52 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • DNA Repair 100%
  • Prostatic Neoplasms 85%
  • Genes 43%
  • Single Nucleotide Polymorphism 38%
  • Prostate Cancer, Hereditary, 7 24%
  11 Citations (Scopus)

• Genetic variation in the immunosuppression pathway genes and breast cancer susceptibility: a pooled analysis of 42,510 cases and 40,577 controls from the Breast Cancer Association Consortium

  Lei, J., Rudolph, A., Moysich, K. B., Behrens, S., Goode, E. L., Bolla, M. K., Dennis, J., Dunning, A. M., Easton, D. F., Wang, Q., Benitez, J., Hopper, J. L., Southey, M. C., Schmidt, M. K., Broeks, A., Fasching, P. A., Haeberle, L., Peto, J., Dos-Santos-Silva, I., Sawyer, E. J., & 31 othersTomlinson, I., Burwinkel, B., Marmé, F., Guénel, P., Truong, T., Bojesen, S. E., Flyger, H., Nielsen, S. F., Nordestgaard, B. G., González-Neira, A., Menéndez, P., Anton-Culver, H., Neuhausen, S. L., Brenner, H., Arndt, V., Meindl, A., Schmutzler, R. K., Brauch, H., Hamann, U., Nevanlinna, H., Fagerholm, R., Dörk, T., Bogdanova, N. V., Mannermaa, A., Hartikainen, J. M., Van Dijck, L., Smeets, A., Flesch-Janys, D., Eilber, U., Radice, P. & Australian Ovarian Study Group, 1 Jan 2016, In: Human Genetics. 135, 1, p. 137-54 18 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Genetic Variation 100%
  • Immunosuppression 93%
  • Breast Neoplasms 66%
  • Genes 41%
  • Interleukin-5 38%
  7 Citations (Scopus)

• Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

  Kar, S. P., Beesley, J., Amin Al Olama, A., Michailidou, K., Tyrer, J., Kote-Jarai, ZS., Lawrenson, K., Lindstrom, S., Ramus, S. J., Thompson, D. J., Kibel, A. S., Dansonka-Mieszkowska, A., Michael, A., Dieffenbach, A. K., Gentry-Maharaj, A., Whittemore, A. S., Wolk, A., Monteiro, A., Peixoto, A., Kierzek, A., & 31 othersCox, A., Rudolph, A., Gonzalez-Neira, A., Wu, A. H., Lindblom, A., Swerdlow, A., Ziogas, A., Ekici, A. B., Burwinkel, B., Karlan, B. Y., Nordestgaard, B. G., Blomqvist, C., Phelan, C., McLean, C., Pearce, C. L., Vachon, C., Cybulski, C., Slavov, C., Stegmaier, C., Maier, C., Ambrosone, C. B., Høgdall, C. K., Teerlink, C. C., Kang, D., Tessier, D. C., Schaid, D. J., Stram, D. O., Høgdall, E., Bojesen, S. E., Kjær, S. K. & ABCTB Investigators, 1 Sept 2016, In: Cancer Discovery. 6, 9, p. 1052-67 16 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Ovarian Neoplasms 100%
  • Prostatic Neoplasms 87%
  • Meta-Analysis 81%
  • Genome 74%
  • Breast Neoplasms 70%
  78 Citations (Scopus)

• High alcohol consumption causes high IgE levels but not high risk of allergic disease

  Lomholt, F. K., Nielsen, S. F. & Nordestgaard, B. G., 1 Nov 2016, In: The Journal of allergy and clinical immunology. 138, 5, p. 1404-1413.e13

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Immunoglobulin E 100%
  • Alcohol Drinking 99%
  • Alcohol Dehydrogenase 23%
  • Odds Ratio 17%
  • Eczema 10%
  14 Citations (Scopus)

• High body mass index and cancer risk

  Benn, M., Tybjærg-Hansen, A., Smith, G. D. & Nordestgaard, B. G., Sept 2016, In: European Journal of Epidemiology. 31, 9, p. 879-92 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Body Mass Index 100%
  • Prostatic Neoplasms 49%
  • Lung Neoplasms 49%
  • Skin Neoplasms 48%
  • Neoplasms 45%
  22 Citations (Scopus)

• High body mass index and risk of exacerbations and pneumonias in individuals with chronic obstructive pulmonary disease: observational and genetic risk estimates from the Copenhagen General Population Study

  Çolak, Y., Afzal, S., Lange, P. & Nordestgaard, B. G., Oct 2016, In: International Journal of Epidemiology. 45, 5, p. 1551-1559 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Chronic Obstructive Pulmonary Disease 100%
  • Pneumonia 90%
  • Body Mass Index 80%
  • Population 44%
  • Alleles 30%
  8 Citations (Scopus)

• High lipoprotein(a) as a possible cause of clinical familial hypercholesterolaemia: a prospective cohort study

  Langsted, A., Kamstrup, P. R., Benn, M., Tybjærg-Hansen, A. & Nordestgaard, B. G., 1 Jul 2016, In: The Lancet Diabetes and Endocrinology. 4, 7, p. 577-587 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Hyperlipoproteinemia Type II 100%
  • Lipoprotein(a) 99%
  • Cohort Studies 55%
  • Prospective Studies 51%
  • Cholesterol 21%
  117 Citations (Scopus)

• Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

  Couch, F. J., Kuchenbaecker, K. B., Michailidou, K., Mendoza-Fandino, G. A., Nord, S., Lilyquist, J., Olswold, C., Hallberg, E., Agata, S., Ahsan, H., Aittomäki, K., Ambrosone, C. B., Andrulis, I. L., Anton-Culver, H., Arndt, V., Arun, B. K., Arver, B., Barile, M., Barkardottir, R. B., Barrowdale, D., & 229 othersBeckmann, L., Beckmann, M. W., Benitez, J., Blank, S. V., Blomqvist, C., Bogdanova, N. V., Bojesen, S. E., Bolla, M. K., Bonanni, B., Brauch, H., Brenner, H., Burwinkel, B., Buys, S., Caldes, T., Caligo, M. A., Canzian, F., Carpenter, J., Chang-Claude, J., Chanock, S. J., Chung, W. K., Claes, K. B. M., Cox, A., Cross, S. S., Cunningham, J. M., Czene, K., Daly, M. B., Damiola, F., Darabi, H., de la Hoya, M., Devilee, P., Diez, O., Ding, Y. C., Dolcetti, R., Domchek, S. M., Dorfling, C. M., dos Santos Silva, I., Dumont, M., Dunning, A. M., Eccles, D. M., Ehrencrona, H., Ekici, A. B., Eliassen, H., Ellis, S. D., Fasching, P. A., Figueroa, J., Flesch-Janys, D., Försti, A., Fostira, F., Foulkes, W. D., Friebel, T. M., Friedman, E., Frost, D., Gabrielson, M., Gammon, M. D., Ganz, P. A., Gapstur, S. M., Garber, J., Gaudet, M., Gayther, S. A., Gerdes, A-M., Ghoussaini, M., Giles, G., Glendon, G., Godwin, A. K., Goldberg, M. S., Goldgar, D. E., González-Neira, A., Greene, M. H., Gronwald, J., Guénel, P., Gunter, M. J., Haeberle, L., Haiman, C. A., Hamann, U., Hansen, T. V. O., Hart, S. N., Healey, S., Heikkinen, T., Henderson, B. E., Herzog, J., Hogervorst, F. B. L., Hollestelle, A., Hooning, M. J., Hoover, R. N., Hopper, J. L., Humphreys, K., Hunter, D. J., Huzarski, T., Imyanitov, E. N., Isaacs, C., Jakubowska, A., James, P., Janavicius, R., Jensen, U. B., John, E. M., Jones, M., Kabisch, M., Kar, S., Karlan, B. Y., Khan, S., Khaw, K-T., Kibriya, M. G., Knight, J. A., Ko, Y-D., Konstantopoulou, I., Kosma, V-M., Kristensen, V., Kwong, A., Laitman, Y., Lambrechts, D., Lazaro, C., Lee, E., Le Marchand, L., Lester, J., Lindblom, A., Lindor, N., Lindstrom, S., Liu, J., Long, J., Lubinski, J., Mai, P. L., Makalic, E., Malone, K. E., Mannermaa, A., Manoukian, S., Margolin, S., Marme, F., Martens, J. W. M., McGuffog, L., Meindl, A., Miller, A., Milne, R. L., Miron, P., Montagna, M., Mazoyer, S., Mulligan, A. M., Muranen, T. A., Nathanson, K. L., Neuhausen, S. L., Nevanlinna, H., Nordestgaard, B. G., Nussbaum, R. L., Offit, K., Olah, E., Olopade, O. I., Olson, J. E., Osorio, A., Park, S. K., Peeters, P. H., Peissel, B., Peterlongo, P., Peto, J., Phelan, C. M., Pilarski, R., Poppe, B., Pylkäs, K., Radice, P., Rahman, N., Rantala, J., Rappaport, C., Rennert, G., Richardson, A. L., Robson, M., Romieu, I., Rudolph, A., Rutgers, E. J., Sánchez, M-J., Santella, R. M., Sawyer, E. J., Schmidt, D. F., Schmidt, M. K., Schmutzler, R. K., Schumacher, F., Scott, R. J., Senter, L., Sharma, P., Simard, J., Singer, C. F., Sinilnikova, O. M., Soucy, P., Southey, M., Steinemann, D., Stenmark-Askmalm, M., Stoppa-Lyonnet, D., Swerdlow, A., Szabo, C. I., Tamimi, R., Tapper, W., Teixeira, M. R., Teo, S-H., Terry, M. B., Thomassen, M., Thompson, D., Tihomirova, L., Toland, A. E., Tollenaar, R. A. E. M., Tomlinson, I., Truong, T., Tsimiklis, H., Teulé, A., Tumino, R., Tung, N., Turnbull, C., Ursin, G., van Deurzen, C. H. M., van Rensburg, E. J., Varon-Mateeva, R., Wang, Z., Wang-Gohrke, S., Weiderpass, E., Weitzel, J. N., Whittemore, A. S., Wildiers, H., Winqvist, R., Yang, X. R., Yannoukakos, D., Yao, S., Zamora, M. P., Zheng, W., Hall, P., Kraft, P., Vachon, C., Slager, S., Chenevix-Trench, G., Pharoah, P. P. D., Monteiro, A. N. A., García-Closas, M., Easton, D. F. & Antoniou, A. C., 27 Apr 2016, In: Nature Communications. 7, p. 1-13 13 p., 11375.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • estrogens 100%
  • loci 66%
  • Estrogen 63%
  • breast 62%
  • cancer 55%
  55 Citations (Scopus)

• Increased Baseline C-Reactive Protein Concentrations Are Associated with Increased Risk of Infections: Results from 2 Large Danish Population Cohorts

  Zacho, J., Benfield, T., Tybjærg-Hansen, A. & Nordestgaard, B. G., Feb 2016, In: Clinical Chemistry. 62, 2, p. 335-42 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • C-Reactive Protein 100%
  • Infections 54%
  • Communicable Diseases 53%
  • Population 44%
  • Genotype 18%
  8 Citations (Scopus)

• Increased Remnant Cholesterol Explains Part of Residual Risk of All-Cause Mortality in 5414 Patients with Ischemic Heart Disease

  Jepsen, A-M. K., Langsted, A., Varbo, A., Bang, L. E., Kamstrup, P. R. & Nordestgaard, B. G., Apr 2016, In: Clinical Chemistry. 62, 4, p. 593-604 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Myocardial Ischemia 100%
  • Cholesterol 83%
  • Mortality 56%
  • LDL Cholesterol 34%
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors 9%
  58 Citations (Scopus)