Anne-Katrine Frank

Research output

Research output per year 2012 2014 2015 2015

• 7 Journal article

Research output per year

Research output per year

Search results

• 2015

  Amplification of pico-scale DNA mediated by bacterial carrier DNA for small-cell-number transcription factor ChIP-seq

  Jakobsen, J. S., Bagger, F. O., Hasemann, M. S., Schuster, M. B., Frank, A-K., Waage, J., Vitting-Seerup, K. & Porse, B. T., 5 Feb 2015, In: BMC Genomics. 16, p. 46

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Bacterial DNA 100%
  • Chromatin Immunoprecipitation Sequencing 99%
  • Transcription Factors 58%
  • Cell Count 57%
  • DNA 43%
  19 Citations (Scopus)

  133 Downloads (Pure)

• Disease evolution and outcomes in familial AML with germline CEBPA mutations

  Tawana, K., Wang, J., Renneville, A., Bödör, C., Hills, R., Loveday, C., Savic, A., Van Delft, F. W., Treleaven, J., Georgiades, P., Uglow, E., Asou, N., Uike, N., Debeljak, M., Jazbec, J., Ancliff, P., Gale, R., Thomas, X., Mialou, V., Döhner, K., & 21 othersBullinger, L., Mueller, B., Pabst, T., Stelljes, M., Schlegelberger, B., Wozniak, E., Iqbal, S., Okosun, J., Araf, S., Frank, A-K., Lauridsen, F. B., Porse, B., Nerlov, C., Owen, C., Dokal, I., Gribben, J., Smith, M., Preudhomme, C., Chelala, C., Cavenagh, J. & Fitzgibbon, J., 3 Sept 2015, In: Blood. 126, 10, p. 1214-23 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Familial Acute Myeloid Leukemia with Mutated Cebpa 100%
  • Germ-Line Mutation 54%
  • Mutation 40%
  • Recurrence 27%
  • High-Throughput Nucleotide Sequencing 19%
  79 Citations (Scopus)

• ERG promotes the maintenance of hematopoietic stem cells by restricting their differentiation

  Knudsen, K. J., Rehn, M. C., Hasemann, M. S., Rapin, N. P. J-P., Bagger, F. O., Ohlsson, E. K., Willer, A., Frank, A-K., Søndergaard, E., Jendholm, L. J., Thorén, L. A. M., Lee, J., Rak, J., Theilgaard-Mønch, K. & Porse, B. T., 15 Sept 2015, In: Genes & Development. 29, p. 1915-1929 15 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Hematopoietic Stem Cells 100%
  • Maintenance 70%
  • Genes 40%
  • Cell Self Renewal 31%
  • Cell Differentiation 30%
  32 Citations (Scopus)
• 2014

  C/EBPα Is Required for Long-Term Self-Renewal and Lineage Priming of Hematopoietic Stem Cells and for the Maintenance of Epigenetic Configurations in Multipotent Progenitors

  Hasemann, M. S., Lauridsen, F. K. B., Waage, J., Jakobsen, J. S., Frank, A-K., Schuster, M. B., Rapin, N. P. J-P., Bagger, F. O., Hoppe, P. S., Schroeder, T. & Porse, B. T., Jan 2014, In: P L o S Genetics (Online). 10, 1, p. 1-10 10 p., e1004079.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • hematopoietic stem cells 100%
  • Hematopoietic Stem Cells 70%
  • epigenetics 70%
  • stem 64%
  • Epigenomics 62%
  58 Citations (Scopus)

  2007 Downloads (Pure)

• Regulation of Trib2 by an E2F1-C/EBPα feedback loop in AML cell proliferation

  Rishi, L., Hannon, M., Salomè, M., Hasemann, M., Frank, A-K., Campos, J., Timoney, J., O'Connor, C., Cahill, M. R., Porse, B. & Keeshan, K., 10 Apr 2014, In: Blood. 123, 15, p. 2389-400 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • CCAAT-Enhancer-Binding Proteins 100%
  • Myeloid Cells 73%
  • Acute Myeloid Leukemia 68%
  • Cell Proliferation 47%
  • Protein 29%
  38 Citations (Scopus)
• 2013

  Lack of the p42 form of C/EBPα leads to spontaneous immortalization and lineage infidelity of committed myeloid progenitors

  Schuster, M. B., Frank, A-K., Bagger, F. O., Rapin, N., Vikesaa, J. & Porse, B. T., Oct 2013, In: Experimental Hematology. 41, 10, p. 882-893 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Granulocyte-Macrophage Progenitor Cells 100%
  • Leukemia 85%
  • Acute Myeloid Leukemia 75%
  • T-Lymphocytes 32%
  • Population 30%
  7 Citations (Scopus)
• 2012

  Phosphorylation of Serine 248 of C/EBPa Is Dispensable for Myelopoiesis but Its Disruption Leads to a Low Penetrant Myeloid Disorder with Long Latency

  Hasemann, M. S., Schuster, M. B., Frank, A-K., Theilgaard-Mönch, K., Pedersen, T. Å., Nerlov, C. & Porse, B. T., 8 Jun 2012, In: P L o S One. 7, 6, p. e38841

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Phosphorylation 100%
  • Carrier Proteins 99%
  • Myelopoiesis 89%
  • CCAAT-Enhancer-Binding Proteins 86%
  • Latency 81%
  3 Citations (Scopus)