Andreas Toft Sørensen

Research output

Research output per year 2005 2005 2008 2009 2011 2013 2014 2017 2018 2019 2019

• 24 Journal article
• 4 Review
• 1 Book chapter
• 1 Encyclopedia chapter

Research output per year

Research output per year

Search results

• 2019

  Differential effects of chemogenetic inhibition on dopamine and norepinephrine neurons in the mouse 5-choice serial reaction time task

  Fitzpatrick, C. M., Runegaard, A. H., Christiansen, S. H., Hansen, N. W., Jørgensen, S. H., McGirr, J. C., de Diego Ajenjo, A., Sørensen, A. T., Perrier, J-F., Petersen, A., Gether, U., Woldbye, D. P. D. & Andreasen, J. T., 2 Mar 2019, In: Progress in Neuro-Psychopharmacology & Biological Psychiatry. 90, 2, p. 264-276 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Designer Drugs 100%
  • Dopaminergic Neurons 92%
  • Attention Deficit Disorder with Hyperactivity 89%
  • Reaction Time 83%
  • Ventral Tegmental Area 80%
  4 Citations (Scopus)

• Modulating Dopamine Signaling and Behavior with Chemogenetics: Concepts, Progress, and Challenges

  Runegaard, A. H., Fitzpatrick, C. M., Woldbye, D. P. D., Andreasen, J. T., Sørensen, A. T. & Gether, U., 1 Apr 2019, In: Pharmacological Reviews. 71, 2, p. 123-156 34 p.

  Research output: Contribution to journal › Review › peer-review

  • Dopamine 100%
  • clozapine N-oxide 59%
  • Designer Drugs 51%
  • Ligands 23%
  • Pharmacology 22%
  18 Citations (Scopus)

• The C-terminal flanking peptide of neuropeptide Y (NPY) is not essential for seizure-suppressant actions of prepro-NPY overexpression in male rats

  Soud, K., Jørgensen, S. H., Woldbye, D. P. D. & Sørensen, A. T., Mar 2019, In: Journal of Neuroscience Research. 97, 3, p. 362-372 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • neuropeptide Y C-terminal flanking peptide 100%
  • preproneuropeptide Y 93%
  • Seizures 37%
  • Neuropeptide Y 25%
  • Peptides 11%
  2 Citations (Scopus)
• 2018

  Inhibition of a Descending Prefrontal Circuit Prevents Ketamine-Induced Stress Resilience in Females

  Dolzani, S. D., Baratta, M. V., Moss, J. M., Leslie, N. L., Tilden, S. G., Sørensen, A. T., Watkins, L. R., Lin, Y. & Maier, S. F., 1 Jan 2018, In: eNeuro. 5, 1, p. 1-18 18 p., e0025-18.2018.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Ketamine 100%
  • Psychological Inhibition 74%
  • Dorsal Raphe Nucleus 66%
  • Designer Drugs 19%
  • Major Depressive Disorder 13%
  16 Citations (Scopus)

  50 Downloads (Pure)

• Locomotor- and Reward-Enhancing Effects of Cocaine Are Differentially Regulated by Chemogenetic Stimulation of Gi-Signaling in Dopaminergic Neurons

  Runegaard, A. H., Sørensen, A. T., Fitzpatrick, C. M., Jørgensen, S. H., Petersen, A. V., Hansen, N. W., Weikop, P., Andreasen, J. T., Mikkelsen, J. D., Perrier, J-F., Woldbye, D., Rickhag, M., Wortwein, G. & Gether, U., 1 May 2018, In: eNeuro. 5, 3, 26 p., e0345.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Ventral Tegmental Area 100%
  • Dopaminergic Neurons 85%
  • Cocaine 82%
  • Reward 79%
  • Psychological Inhibition 47%
  20 Citations (Scopus)

  90 Downloads (Pure)

• Npas4 Is a Critical Regulator of Learning-Induced Plasticity at Mossy Fiber-CA3 Synapses during Contextual Memory Formation

  Weng, F-J., Garcia, R. I., Lutzu, S., Alviña, K., Zhang, Y., Dushko, M., Ku, T., Zemoura, K., Rich, D., Garcia-Dominguez, D., Hung, M., Yelhekar, T. D., Sørensen, A. T., Xu, W., Chung, K., Castillo, P. E. & Lin, Y., 7 Mar 2018, In: Neuron. 97, 5, p. 1137-1152 16 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Synapses 100%
  • Pyramidal Cells 91%
  • Learning 79%
  • Memory 79%
  • Hippocampal Mossy Fibers 34%
  22 Citations (Scopus)
• 2017

  Altered Chloride Homeostasis Decreases the Action Potential Threshold and Increases Hyperexcitability in Hippocampal Neurons

  Sørensen, A. T., Ledri, M., Melis, M., Nikitidou Ledri, L., Andersson, M. & Kokaia, M., 1 Nov 2017, In: eNeuro. 4, 6, e0172-17.2017 1–10.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Chlorides 100%
  • Action Potentials 85%
  • Homeostasis 69%
  • Neurons 57%
  • GABA-A Receptors 37%
  13 Citations (Scopus)

  50 Downloads (Pure)

• Chemogenetic Modulation of G Protein-Coupled Receptor Signalling in Visual Attention Research

  Jørgensen, S. H., Fitzpatrick, C. M., Gether, U., Woldbye, D. P. D. & Sørensen, A. T., Nov 2017, In: Basic & Clinical Pharmacology & Toxicology. 121, 5, p. 373-381 9 p.

  Research output: Contribution to journal › Review › peer-review

  • Designer Drugs 100%
  • Designer Drug 98%
  • G-Protein-Coupled Receptors 66%
  • Technology 21%
  • Disorder 18%
  3 Citations (Scopus)
• 2016

  A robust activity marking system for exploring active neuronal ensembles

  Sorensen, A. T., Cooper, Y. A., Baratta, M. V., Weng, F-J., Zhang, Y., Ramamoorthi, K., Fropf, R., LaVerriere, E., Xue, J., Young, A., Schneider, C., Gotzsche, C. R., Hemberg, M., Yin, J. C. P., Maier, S. F. & Lin, Y., 23 Sept 2016, In: eLife. 5, 9, 28 p., e13918.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Marking 100%
  • Statistical Ensemble 72%
  • Dependovirus 45%
  • Neurons 44%
  • Diptera 39%
  51 Citations (Scopus)

  97 Downloads (Pure)
• 2015

  Differential Effect of Neuropeptides on Excitatory Synaptic Transmission in Human Epileptic Hippocampus

  Ledri, M., Sorensen, A. T., Madsen, M. G., Christiansen, S. H., Ledri, L. N., Cifra, A., Bengzon, J., Lindberg, E., Pinborg, L. H., Jespersen, B., Gotzsche, C. R., Woldbye, D. P. D., Andersson, M. & Kokaia, M., 1 Jul 2015, In: Journal of Neuroscience. 35, 26, p. 9622-9631 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Neuropeptides 100%
  • Galanin Receptors 93%
  • Synaptic Transmission 91%
  • Galanin 79%
  • Hippocampus 78%
  21 Citations (Scopus)
• 2014

  Noninvasive optical inhibition with a red-shifted microbial rhodopsin

  Chuong, A. S., Miri, M. L., Busskamp, V., Matthews, G. A. C., Acker, L. C., Sørensen, A. T., Young, A., Klapoetke, N. C., Henninger, M. A., Kodandaramaiah, S. B., Ogawa, M., Ramanlal, S. B., Bandler, R. C., Allen, B. D., Forest, C. R., Chow, B. Y., Han, X., Lin, Y., Tye, K. M., Roska, B., & 2 othersCardin, J. A. & Boyden, E. S., Aug 2014, In: Nature Neuroscience. 17, 8, p. 1123-1129 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Microbial Rhodopsins 100%
  • Jaw 55%
  • Optogenetics 35%
  • Neurosciences 29%
  • Light 28%
  281 Citations (Scopus)

• Optogenetic inhibition of chemically induced hypersynchronized bursting in mice

  Berglind, F., Ledri, M., Sørensen, A. T., Nikitidou, L., Melis, M., Bielefeld, P., Kirik, D., Deisseroth, K., Andersson, M. & Kokaia, M., May 2014, In: Neurobiology of Disease. 65, p. 133-141 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Optogenetics 100%
  • Seizures 59%
  • Epilepsy 48%
  • Hippocampus 30%
  • Neurons 23%
  31 Citations (Scopus)

• Optogenetics reveal delayed afferent synaptogenesis on grafted human-induced pluripotent stem cell-derived neural progenitors

  Avaliani, N., Sørensen, A. T., Ledri, M., Bengzon, J., Koch, P., Brüstle, O., Deisseroth, K., Andersson, M. & Kokaia, M., 1 Dec 2014, In: Stem Cells. 32, 12, p. 3088-98 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Optogenetics 100%
  • Neuroepithelial Cells 97%
  • Induced Pluripotent Stem Cells 86%
  • Stem Cells 56%
  • Neurons 47%
  38 Citations (Scopus)
• 2013

  Jasper’s Basic mechanisms of the Epilepsies: Gene Therapy of Focal-Onset Epilepsy Using Adeno-Associated Virus Vector-Mediated Overexpression of Neuropeptide Y

  Noe, F., Sørensen, A. T., Kokaia, M. & Vezzani, A., 2013, Jasper's Basic Mechanisms of the Epilepsies: Gene Therapy of Focal-Onset Epilepsy Using Adeno-Associated Virus Vector-Mediated Overexpression of Neuropeptide Y. Noebels, J. L., Avoli, M., Rogawski, M. A., Olsen, R. W. & Delgado-Escueta, A. V. (eds.). 4 ed. Oxford University Press, p. 1139-1149 11 p.

  Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

• Novel approaches to epilepsy treatment

  Sørensen, A. T. & Kokaia, M., Jan 2013, In: Epilepsia. 54, 1, p. 1-10 10 p.

  Research output: Contribution to journal › Review › peer-review

  • Epilepsy 100%
  • Partial Epilepsy 46%
  • Seizures 46%
  • Optogenetics 25%
  • Drug Resistant Epilepsy 22%
  54 Citations (Scopus)
• 2012

  Combined gene overexpression of neuropeptide Y and its receptor Y5 in the hippocampus suppresses seizures.

  Gøtzsche, C. R., Nikitidou, L., Sørensen, A. T., Olesen, M. V., Sørensen, G., Christiansen, S. H. O., Ängehagen, M., Woldbye, D. P. D. & Kokaia, M., Jan 2012, In: Neurobiology of Disease. 45, p. 288-96 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Neuropeptide Y Receptors 100%
  • Hippocampus 53%
  • Seizures 51%
  • neuropeptide Y5 receptor 39%
  • Neuropeptide Y 38%
  35 Citations (Scopus)
• 2011

  Activity-dependent long-term plasticity of afferent synapses on grafted stem/progenitor cell-derived neurons

  Sørensen, A. T., Rogelius, N., Lundberg, C. & Kokaia, M., Jun 2011, In: Experimental Neurology. 229, 2, p. 274-81 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Synapses 100%
  • Stem Cells 80%
  • Neurons 67%
  • Excitatory Postsynaptic Potentials 42%
  • Brain Diseases 23%
  8 Citations (Scopus)

• Functional integration of grafted neural stem cell-derived dopaminergic neurons monitored by optogenetics in an in vitro Parkinson model

  Tønnesen, J., Parish, C. L., Sørensen, A. T., Andersson, A., Lundberg, C., Deisseroth, K., Arenas, E., Lindvall, O. & Kokaia, M., 4 Mar 2011, In: PLOS ONE. 6, 3, p. e17560

  Research output: Contribution to journal › Journal article › Research › peer-review

  • neural stem cells 100%
  • optogenetics 94%
  • Functional Integration 93%
  • Dopamine 92%
  • Stem cells 85%
  77 Citations (Scopus)

• The treatment of neurological diseases under a new light: the importance of optogenetics

  Kokaia, M. & Sørensen, A. T., Jan 2011, In: Drugs of Today. 47, 1, p. 53-62 10 p.

  Research output: Contribution to journal › Review › peer-review

  • Optogenetics 100%
  • Channelrhodopsins 58%
  • Light 54%
  • Neurons 47%
  • Action Potentials 34%
  11 Citations (Scopus)

• Tuning afferent synapses of hippocampal interneurons by neuropeptide Y

  Ledri, M., Sørensen, A. T., Erdelyi, F., Szabo, G. & Kokaia, M., Feb 2011, In: Hippocampus. 21, 2, p. 198-211 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Neuropeptide Y 100%
  • Interneurons 91%
  • Synapses 79%
  • Cholecystokinin 67%
  • neuropeptide Y2 receptor 16%
  12 Citations (Scopus)
• 2010

  Adeno-associated viral vector-induced overexpression of neuropeptide Y Y2 receptors in the hippocampus suppresses seizures

  Woldbye, D. P. D., Ängehagen, M., Gøtzsche, C. R., Elbrønd-Bek, H., Sørensen, A. T., Christiansen, S. H. O., Olesen, M. V., Nikitidou, L., Hansen, T. V. O., Kanter-Schlifke, I. & Kokaia, M., Sept 2010, In: Brain. 133, 9, p. 2778-88 10 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • neuropeptide Y2 receptor 100%
  • Neuropeptide Y Receptors 88%
  • Neuropeptide Y 48%
  • Hippocampus 47%
  • Seizures 45%
  64 Citations (Scopus)
• 2009

  Encyclopedia of Basic Epilepsy Research: Epilepsy and Gene Therapy: Resculpturing synaptic transmission with neuropeptides

  Kokaia, M. & Sørensen, A. T., 27 May 2009, Encyclopedia of Basic Epilepsy Research: Epilepsy and Gene Therapy: Resculpturing synaptic transmission with neuropeptides. Schwartzkroin, PA. (ed.). Elsevier Ltd. Academic Press, Vol. 3. p. 1430-34 5 p.

  Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Research › peer-review

  8 Citations (Scopus)

• Hippocampal NPY gene transfer attenuates seizures without affecting epilepsy-induced impairment of LTP

  Sørensen, A. T., Nikitidou, L., Ledri, M., Lin, E-J. D., During, M. J., Kanter-Schlifke, I. & Kokaia, M., Feb 2009, In: Experimental Neurology. 215, 2, p. 328-33 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Psychology Transfer 100%
  • Neuropeptide Y 99%
  • Long-Term Potentiation 97%
  • Epilepsy 72%
  • Seizures 66%
  53 Citations (Scopus)

• Optogenetic control of epileptiform activity

  Tønnesen, J., Sørensen, A. T., Deisseroth, K., Lundberg, C. & Kokaia, M., 21 Jul 2009, In: Proceedings of the National Academy of Sciences of the United States of America. 106, 29, p. 12162-7 6 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Natronomonas 100%
  • Optogenetics 64%
  • Neurons 30%
  • Halorhodopsins 29%
  • Epilepsy 27%
  175 Citations (Scopus)
• 2008

  Activity-dependent volume transmission by transgene NPY attenuates glutamate release and LTP in the subiculum

  Sørensen, A. T., Kanter-Schlifke, I., Lin, E-J. D., During, M. J. & Kokaia, M., Oct 2008, In: Molecular and Cellular Neuroscience. 39, 2, p. 229-37 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Neuropeptide Y 100%
  • Transgenes 87%
  • Glutamic Acid 75%
  • Hippocampus 69%
  • Synapses 39%
  19 Citations (Scopus)

• NPY gene transfer in the hippocampus attenuates synaptic plasticity and learning

  Sørensen, A. T., Kanter-Schlifke, I., Carli, M., Balducci, C., Noe, F., During, M. J., Vezzani, A. & Kokaia, M., 2008, In: Hippocampus. 18, 6, p. 564-74 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Psychology Transfer 100%
  • Neuropeptide Y 99%
  • Neuronal Plasticity 81%
  • Hippocampus 68%
  • Learning 62%
  45 Citations (Scopus)

• Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice

  Parish, C. L., Castelo-Branco, G., Rawal, N., Tonnesen, J., Sorensen, A. T., Salto, C., Kokaia, M., Lindvall, O. & Arenas, E., Jan 2008, In: The Journal of Clinical Investigation. 118, 1, p. 149-60 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Neural Stem Cells 100%
  • Dopaminergic Neurons 93%
  • Mesencephalon 92%
  • Cell- and Tissue-Based Therapy 84%
  • Dopamine 75%
  133 Citations (Scopus)
• 2007

  Galanin gene transfer curtails generalized seizures in kindled rats without altering hippocampal synaptic plasticity

  Kanter-Schlifke, I., Toft Sørensen, A., Ledri, M., Kuteeva, E., Hökfelt, T. & Kokaia, M., 19 Dec 2007, In: Neuroscience. 150, 4, p. 984-92 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Galanin 100%
  • Neuronal Plasticity 70%
  • Seizures 57%
  • Genes 29%
  • Synapses 22%
  30 Citations (Scopus)
• 2005

  Differential suppression of seizures via Y2 and Y5 neuropeptide Y receptors

  Woldbye, D. P. D., Nanobashvili, A., Sørensen, A. V., Husum, H., Bolwig, T. G., Sørensen, G., Ernfors, P., Kokaia, M. & Sørensen, G., 1 Dec 2005, In: Neurobiology of Disease. 20, 3, p. 760-72 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Neuropeptide Y Receptors 100%
  • Neuropeptide Y 61%
  • Seizures 51%
  • Kainic Acid 31%
  • L 152804 30%
  45 Citations (Scopus)

• Functional properties and synaptic integration of genetically labelled dopaminergic neurons in intrastriatal grafts

  Sørensen, A. T., Thompson, L., Kirik, D., Björklund, A., Lindvall, O. & Kokaia, M., May 2005, In: European Journal of Neuroscience. 21, 10, p. 2793-9 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Dopaminergic Neurons 100%
  • Transplants 59%
  • Action Potentials 37%
  • Transgenic Mice 24%
  • Dopamine 23%
  30 Citations (Scopus)