Anders Elm Pedersen

2009

A comparative study of transfection methods for RNA interference in bone marrow-derived murine dendritic cells

Pedersen, C. D., Fang, J. J. & Pedersen, A. E., 2009, In: Scandinavian Journal of Immunology. 70, 5, p. 447-56 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

7 Citations (Scopus)

Addition of interferon-alpha to a standard maturation cocktail induces CD38 up-regulation and increases dendritic cell function

Trepiakas, R., Pedersen, A. E., Met, O. & Svane, I. M., 2009, In: Vaccine. 27, 16, p. 2213-9 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

27 Citations (Scopus)

Blockage of the neurokinin 1 receptor and capsaicin-induced ablation of the enteric afferent nerves protect SCID mice against T-cell-induced chronic colitis

Gad, M., Pedersen, A. E., Kristensen, N. N., Fernandez, C. D. F. & Claesson, M. H., 2009, In: Inflammatory Bowel Diseases. 15, 8, p. 1174-82 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

35 Citations (Scopus)

CD25 shedding by human natural occurring CD4+CD25+ regulatory T cells does not inhibit the action of IL-2

Pedersen, A. E. & Lauritsen, J. P. H., 2009, In: Scandinavian Journal of Immunology. 70, 1, p. 40-3 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

22 Citations (Scopus)

Genome-wide gene expression profiling of SCID mice with T-cell-mediated Colitis

Brudzewsky, D., Pedersen, A. E., Claesson, M. H., Gad, M., Kristensen, N. N., Lage, K., Jensen, T., Tommerup, N., Larsen, L. A., Knudsen, S. & Tümer, Z., 2009, In: Scandinavian Journal of Immunology. 69, 5, p. 437-46 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

Immune responses in patients with metastatic renal cell carcinoma treated with dendritic cells pulsed with tumor lysate

Soleimani, A., Berntsen, A., Svane, I. M. & Pedersen, A. E., 2009, In: Scandinavian Journal of Immunology. 70, 5, p. 481-9 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

32 Citations (Scopus)

Induction of novel CD8+ T-cell responses during chronic untreated HIV-1 infection by immunization with subdominant cytotoxic T-lymphocyte epitopes

Kloverpris, H., Karlsson, I., Bonde, J., Thorn, M., Vinner, L., Pedersen, A., Hentze, J., Andresen, B., Svane, I., Gerstoft, J., Kronborg, G., Fomsgaard, A., Kloverpris, H., Karlsson, I., Bonde, J., Thorn, M., Vinner, L., Pedersen, A. E., Hentze, J. L., Andresen, B. S., & 4 othersSvane, I. M., Gerstoft, J., Kronborg, G. & Fomsgaard, A., 2009, In: AIDS. 23, 11, p. 1329-40 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

46 Citations (Scopus)

2008

Alterations in p53-specific T cells and other lymphocyte subsets in breast cancer patients during vaccination with p53-peptide loaded dendritic cells and low-dose interleukin-2.

Svane, I. M., Pedersen, A. E., Nikolajsen, K. & Zocca, M-B., 2008, In: Vaccine. 26, 36, p. 4716-24 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

Comparison of alpha-Type-1 polarizing and standard dendritic cell cytokine cocktail for maturation of therapeutic monocyte-derived dendritic cell preparations from cancer patients.

Trepiakas, R., Pedersen, A. E., Met, O., Hansen, M. H., Berntsen, A. & Svane, I. M., 2008, In: Vaccine. 26, 23, p. 2824-32 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

28 Citations (Scopus)

Dexamethasone/1alpha-25-dihydroxyvitamin D3-treated dendritic cells suppress colitis in the SCID T-cell transfer model

Pedersen, A. E., Schmidt, E. G. W., Gad, M., Poulsen, S. S. & Claesson, M. H., 2008, In: Immunology.

Research output: Contribution to journal › Journal article › Research › peer-review

29 Citations (Scopus)

Therapeutic dendritic cell vaccination of patients with metastatic renal cell carcinoma: a clinical phase 1/2 trial.

Berntsen, A., Trepiakas, R., Wenandy, L., Geertsen, P. F., thor Straten, P., Andersen, M. H., Pedersen, A. E., Claesson, M. H., Lorentzen, T., Johansen, J. S. & Svane, I. M., 2008, In: Journal of Immunotherapy. 31, 8, p. 771-80 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

86 Citations (Scopus)

2007

Addition of TAT protein transduction domain and GrpE to human p53 provides soluble fusion proteins that can be transduced into dendritic cells and elicit p53-specific T-cell responses in HLA-A*0201 transgenic mice.

Justesen, S., Buus, S., Claesson, M. H. & Pedersen, A. E., 2007, In: Immunology. 122, 3, p. 326-34 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

11 Citations (Scopus)

CTLA-4 blockade during dendritic cell based booster vaccination influences dendritic cell survival and CTL expansion.

Pedersen, A. E. & Ronchese, F., 2007, In: Journal of Immune Based Therapies and Vaccines. 5, p. 9

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

The potential for induction of autoimmune disease by a randomly-mutated self-antigen.

Pedersen, A. E., 2007, In: Medical Hypotheses. 68, 6, p. 1240-6 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2 Citations (Scopus)

Tolerogenic dendritic cells pulsed with enterobacterial extract suppress development of colitis in the severe combined immunodeficiency transfer model

Pedersen, A. E., Gad, M., Kristensen, N. N., Haase, C., Nielsen, C. H. & Claesson, M. H., 2007, In: Immunology. 121, 4, p. 526-32 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

Vaccination with p53 peptide-pulsed dendritic cells is associated with disease stabilization in patients with p53 expressing advanced breast cancer; monitoring of serum YKL-40 and IL-6 as response biomarkers.

Svane, I. M., Pedersen, A. E., Johansen, J. S., Johnsen, H. E., Nielsen, D., Kamby, C., Ottesen, S., Balslev, E., Gaarsdal, E., Nikolajsen, K. & Claesson, M. H., 2007, In: Cancer Immunology, Immunotherapy. 56, 9, p. 1485-99 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

77 Citations (Scopus)

2006

1,25-Dihydroxyvitamin D3 and Modulation of Dendritic Cells

Pedersen, A. E. & Stolzt, V. D., 2006, Vitamin D: New Research. Nova Publishers, Vol. 3. p. 41-57 16 p.

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

Characterization of monocyte-derived dendritic cells maturated with IFN-alpha.

Svane, I. M., Nikolajsen, K., Walter, M. R., Buus, S., Gad, M., Claesson, M. H. & Pedersen, A. E., 2006, In: Scandinavian Journal of Immunology. 63, 3, p. 217-22 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

19 Citations (Scopus)

Clinical Dendritic Cell Cancer Vaccination

Pedersen, A. E., Berntsen, A., Svane, I. M. & Elliot, N., 2006, Cancer Vaccines: New Research. Nova Publishers, Vol. 6. p. 91-112 21 p.

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

CTL epitopes for influenza A including the H5N1 bird flu; genome-, pathogen-, and HLA-wide screening.

Wang, M., Lamberth, K., Harndahl, M., Røder, G., Stryhn, A., Larsen, M. V., Nielsen, M., Lundegaard, C., Tang, S. T., Dziegiel, M. H., Rosenkvist, J., Pedersen, A. E., Buus, S., Claesson, M. H. & Lund, O., 2006, In: Vaccine. 25, 15, p. 2823-31 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

91 Citations (Scopus)

Dendritcellebaserede cancervacciner--klinisk anvendelse.

Translated title of the contribution: Dendrite cell-based cancer vaccines--clinical applicationSvane, I. M., Berntsen, A., Trepiakas, R. & Pedersen, A. E., 2006, In: Ugeskrift for læger. 168, 14, p. 1415-20 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

The effect of a therapeutic dendritic cell-based cancer vaccination depends on the blockage of CTLA-4 signaling.

Met, O., Wang, M., Pedersen, A. E., Nissen, M. H., Buus, S. & Claesson, M. H., 2006, In: Cancer Letters. 231, 2, p. 247-56 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

42 Citations (Scopus)

2005

Cancer vaccination studies with peptide pulsed dendritic cells

Pedersen, A. E., 2005, Vester Kopi.

Research output: Book/Report › Ph.D. thesis

Phenotypic and functional characterization of clinical grade dendritic cells generated from patients with advanced breast cancer for therapeutic vaccination.

Pedersen, A. E., Thorn, M., Gad, M., Walter, M. R., Johnsen, H. E., Gaarsdal, E., Nikolajsen, K., Buus, S., Claesson, M. H. & Svane, I. M., 2005, In: Scandinavian Journal of Immunology. 61, 2, p. 147-56 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

51 Citations (Scopus)

Treatment of transplanted CT26 tumour with dendritic cell vaccine in combination with blockade of vascular endothelial growth factor receptor 2 and CTLA-4.

Pedersen, A. E., Buus, S. & Claesson, M. H., 2005, In: Cancer Letters. 235, 2, p. 229-38 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

43 Citations (Scopus)

2004

Changes in protein expression in p53 deleted spontaneous thymic lymphomas.

Honoré, B., Vorum, H., Pedersen, A. E., Buus, S. & Claësson, M. H., 2004, In: Experimental Cell Research. 295, 1, p. 91-101 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

17 Citations (Scopus)

Demonstration of strong enterobacterial reactivity of CD4+CD25- T cells from conventional and germ-free mice which is counter-regulated by CD4+CD25+ T cells.

Gad, M., Pedersen, A. E., Kristensen, N. N. & Claesson, M. H., 2004, In: European Journal of Immunology. 34, 3, p. 695-704 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

32 Citations (Scopus)

Induction of regulatory dendritic cells by dexamethasone and 1alpha,25-Dihydroxyvitamin D(3).

Pedersen, A. E., Gad, M., Walter, M. R. & Claesson, M. H., 2004, In: Immunology Letters. 91, 1, p. 63-9 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

84 Citations (Scopus)

Vaccination with p53-peptide-pulsed dendritic cells, of patients with advanced breast cancer: report from a phase I study.

Svane, I. M., Pedersen, A. E., Johnsen, H. E., Nielsen, D., Kamby, C., Gaarsdal, E., Nikolajsen, K., Buus, S. & Claesson, M. H., 2004, In: Cancer Immunology, Immunotherapy. 53, 7, p. 633-41 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

98 Citations (Scopus)

2003

Dendritic cells in peripheral tolerance and immunity.

Gad, M., Claesson, M. H. & Pedersen, A. E., 2003, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 111, 7-8, p. 766-75 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

41 Citations (Scopus)

Tumor-associated antigens identified by mRNA expression profiling as tumor rejection epitopes.

Andersen, M., Ruhwald, M., Thorn, M., Pedersen, A., Mathiassen, S., Buus, S. & Claesson, M., 2003, In: Journal of Immune Based Therapies and Vaccines. 1, 1, p. 1

Research output: Contribution to journal › Journal article › Research › peer-review

6 Citations (Scopus)

1999

MHC class I cross-talk with CD2 and CD28 induces specific intracellular signalling and leads to growth retardation and apoptosis via a p56(lck)-dependent mechanism.

Ruhwald, M., Pedersen, A. E. & Claesson, M. H., 1999, In: Experimental and Clinical Immunogenetics. 16, 4, p. 199-211 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

MHC-I-induced apoptosis in human B-lymphoma cells is dependent on protein tyrosine and serine/threonine kinases.

Pedersen, A. E., Bregenholt, S., Johansen, B., Skov, S. & Claesson, M. H., 1999, In: Experimental Cell Research. 251, 1, p. 128-34 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Signal transduction by the major histocompatibility complex class I molecule.

Pedersen, A. E., Skov, S., Bregenholt, S., Ruhwald, M. & Claesson, M. H., 1999, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 107, 10, p. 887-95 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

1998

Protein tyrosine kinases p53/56lyn and p72syk in MHC class I-mediated signal transduction in B lymphoma cells.

Pedersen, A. E., Bregenholt, S., Skov, S., Vrang, M. L. & Claesson, M. H., 1998, In: Experimental Cell Research. 240, 1, p. 144-50 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

1996

MHC class I is functionally associated with antigen receptors in human T and B lymphomas.

Pedersen, A. E., Jacoby, B. F., Skov, S. & Claesson, M. H., 1996, In: Cellular Immunology. 173, 2, p. 295-302 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

12 Citations (Scopus)

Anders Elm Pedersen

Research output

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