@article{48e8e808675540eeb351170bcb6d85f0,
title = "Uranyl salts as photochemical agents for cleavage of DNA and probing of protein-DNA contacts",
abstract = "Single-strand DNA nicks are induced by uranyl nitrate or uranyl acetate in combination with long-wavelength (lambda approximately 420 nm) ultraviolet irradiation. The nicks occur randomly with respect to the DNA sequence. Using the lambda-repressor/ORI operator DNA system it is shown that uranyl salts can be used to photofootprint protein contacts with the DNA backbone.",
keywords = "Bacteriophage lambda/analysis, Base Sequence, DNA/drug effects, DNA, Superhelical/drug effects, Electrophoresis, Polyacrylamide Gel, Operator Regions, Genetic, Organometallic Compounds/pharmacology, Photochemistry, Plasmids, Proteins/metabolism, Repressor Proteins/metabolism, Ultraviolet Rays, Uranium/pharmacology, Uranyl Nitrate/pharmacology",
author = "O Buchardt and Nielsen, {Peter E.}",
year = "1988",
month = aug,
day = "1",
language = "English",
volume = "235",
pages = "122--4",
journal = "FEBS Letters",
issn = "0014-5793",
publisher = "JohnWiley & Sons Ltd",
number = "1-2",
}