Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects

Niels Grarup, Mette K Andersen, Camilla H Andreasen, Anders Albrechtsen, Knut Borch-Johnsen, Torben Jørgensen, Johan Auwerx, Ole Schmitz, Torben Hansen, Oluf Pedersen

41 Citationer (Scopus)

Abstract

The type 2 iodothyronine deiodinase (D2) catalyzes the conversion of T(4) to the active form of thyroid hormone, which is a critical regulator of thermogenesis and glucose metabolism. A Thr92Ala polymorphism in the gene encoding D2 (DIO2) has been reported to associate with insulin resistance.
OriginalsprogEngelsk
TidsskriftJournal of Clinical Endocrinology and Metabolism
Vol/bind92
Udgave nummer1
Sider (fra-til)363-6
Antal sider4
ISSN0021-972X
DOI
StatusUdgivet - 2007

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