@article{557a419250cc4c5b92b7fc28147ebefe,
title = "Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies",
abstract = "In the present study, we aimed to validate the type 2 diabetes susceptibility alleles identified in six recent genome-wide association studies in the HHEX/KIF11/IDE (rs1111875), CDKN2A/B (rs10811661), and IGF2BP2 (rs4402960) loci, as well as the intergenic rs9300039 variant. Furthermore, we aimed to characterize quantitative metabolic risk phenotypes of the four variants.",
keywords = "Adult, Cohort Studies, Cyclin-Dependent Kinase Inhibitor p15, Cyclin-Dependent Kinase Inhibitor p16, Denmark, Diabetes Mellitus, Type 2, European Continental Ancestry Group, Genetic Predisposition to Disease, Genetic Variation, Genome, Human, Glucose Intolerance, Homeodomain Proteins, Humans, Insulin, Insulin-Like Growth Factor Binding Protein 2, Introns, Middle Aged, Reference Values, Reproducibility of Results, Transcription Factors",
author = "Niels Grarup and Rose, {Chrisian S} and Andersson, {Ehm A} and Gitte Andersen and Nielsen, {Arne L} and Anders Albrechtsen and Clausen, {Jesper O} and Rasmussen, {Signe S} and Torben J{\o}rgensen and Annelli Sandbaek and Torsten Lauritzen and Ole Schmitz and Torben Hansen and Oluf Pedersen",
year = "2007",
doi = "10.2337/db07-0856",
language = "English",
volume = "56",
pages = "3105--11",
journal = "Diabetes",
issn = "0012-1797",
publisher = "American Diabetes Association",
number = "12",
}
