@article{24188f258aa04d0794c4911293b3a5d7,
title = "Genetic analysis of the estrogen-related receptor alpha and studies of association with obesity and type 2 diabetes",
abstract = "The estrogen-related receptor alpha (ERRalpha or NR3B1) is a transcription factor from the nuclear receptor super-family, group III. The gene encoding ERRalpha (ESRRA) is located on chromosome 11q13, a region showing genetic linkage to body mass index and fat percentage. Through interaction with the peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha), ERRalpha regulates key enzymes involved in the beta-oxidation of fatty acids.",
keywords = "Aged, Anthropometry, Blood Glucose, Body Constitution, Chromosomes, Human, Pair 11, DNA Mutational Analysis, Diabetes Mellitus, Type 2, Estrogen Receptor alpha, Female, Genetic Predisposition to Disease, Heat-Shock Proteins, Humans, Insulin, Linkage Disequilibrium, Lipids, Male, Middle Aged, Obesity, Polymorphism, Single Nucleotide, Quantitative Trait, Heritable, Transcription Factors",
author = "Larsen, {L H} and Rose, {C S} and T Spars{\o} and J Overgaard and Torekov, {Signe S{\o}rensen} and N Grarup and Jensen, {D P} and Anders Albrechtsen and G Andersen and J Ek and C Gl{\"u}mer and K Borch-Johnsen and T J{\o}rgensen and T Hansen and O Pedersen",
year = "2007",
doi = "10.1038/sj.ijo.0803408",
language = "English",
volume = "31",
pages = "365--70",
journal = "International Journal of Obesity",
issn = "0307-0565",
publisher = "nature publishing group",
number = "2",
}
