Electromembrane extraction: Overview of the last decade

TY - JOUR

T1 - Electromembrane extraction: Overview of the last decade

AU - Drouin, Nicolas

AU - Kuban, Pavel

AU - Rudaz, Serge

AU - Pedersen-Bjergaard, Stig

AU - Schappler, Julie

PY - 2019/4

Y1 - 2019/4

N2 - Sample preparation is a crucial step in any bioanalytical workflow. Nowadays, microextractions are very popular because of the reduction of the organic solvent and sample volumes, the analysis time, and the operating costs. Electromembrane extraction (EME) is one of the most recently reported liquid phase microextraction (LPME) techniques and was first described in 2006. It is based on the application of an electric field between two aqueous compartments separated by a layer of water-immiscible organic solvent, reducing the time needed for the extraction process to a few minutes, enabling extraction selectivity towards a broad range of molecule polarity (−5 < Log P < 5), recoveries up to 100%, and enrichment up to 100-fold. In this paper, EME literature was reviewed with special emphasis on recent mass transfer theory, and how this theory affects method development and the different technical configurations.

AB - Sample preparation is a crucial step in any bioanalytical workflow. Nowadays, microextractions are very popular because of the reduction of the organic solvent and sample volumes, the analysis time, and the operating costs. Electromembrane extraction (EME) is one of the most recently reported liquid phase microextraction (LPME) techniques and was first described in 2006. It is based on the application of an electric field between two aqueous compartments separated by a layer of water-immiscible organic solvent, reducing the time needed for the extraction process to a few minutes, enabling extraction selectivity towards a broad range of molecule polarity (−5 < Log P < 5), recoveries up to 100%, and enrichment up to 100-fold. In this paper, EME literature was reviewed with special emphasis on recent mass transfer theory, and how this theory affects method development and the different technical configurations.

M3 - Journal article

SN - 0165-9936

VL - 113

SP - 357

JO - Trends in Analytical Chemistry

JF - Trends in Analytical Chemistry

ER -