Abstract
Sample preparation is a crucial step in any bioanalytical workflow. Nowadays, microextractions are very popular because of the reduction of the organic solvent and sample volumes, the analysis time, and the operating costs. Electromembrane extraction (EME) is one of the most recently reported liquid phase microextraction (LPME) techniques and was first described in 2006. It is based on the application of an electric field between two aqueous compartments separated by a layer of water-immiscible organic solvent, reducing the time needed for the extraction process to a few minutes, enabling extraction selectivity towards a broad range of molecule polarity (−5 < Log P < 5), recoveries up to 100%, and enrichment up to 100-fold. In this paper, EME literature was reviewed with special emphasis on recent mass transfer theory, and how this theory affects method development and the different technical configurations.
| Original language | English |
|---|---|
| Journal | Trends in Analytical Chemistry |
| Volume | 113 |
| Pages (from-to) | 357 |
| Number of pages | 363 |
| ISSN | 0165-9936 |
| Publication status | Published - Apr 2019 |