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Efficient pH-independent sequence-specific DNA binding by pseudoisocytosine-containing bis-PNA
K L Dueholm, O Buchardt, J Coull,
Peter E. Nielsen
Transcription, RNA, and Gene Medicine Program
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Keyphrases
DNA Binding
100%
Sequence-specific DNA Binding
100%
Independent Sequence
100%
PH-independent
100%
Melting Transition
50%
Peptide nucleic Acid
50%
Amino
50%
Hysteresis
50%
Strand Invasion
50%
Nucleobases
50%
Single-stranded DNA (ssDNA)
50%
Continuous Synthesis
50%
High Thermal Stability
50%
Flexible Linker
50%
Hoogsteen
50%
Complementary Oligonucleotide
50%
Biochemistry, Genetics and Molecular Biology
DNA Binding
100%
Melting Point
33%
Oligonucleotide
33%
Nucleobase
33%
N-Terminus
33%
Peptide Nucleic Acid
33%
Thermostability
33%