Early- and late-onset pelvic inflammatory disease among women with cervical Chlamydia trachomatis infection at the time of induced abortion--a follow-up study

TY - JOUR

T1 - Early- and late-onset pelvic inflammatory disease among women with cervical Chlamydia trachomatis infection at the time of induced abortion--a follow-up study

AU - Sørensen, Jette Led

AU - Thranov, I

AU - Hoff, G

AU - Dirach, J

PY - 1994

Y1 - 1994

N2 - After termination of a double-blind, randomized study on erythromycin in the prevention of post-abortion infection, 34 women (14 treated with erythromycin, 20 not treated with erythromycin) harbouring Chlamydia trachomatis were followed up within 6 weeks and again 2 to 24 months after the abortion in order to detect an early- and late-onset pelvic inflammatory disease (PID). For statistical analysis survival analysis by Kaplan-Meir estimates and Mantel-Cox test were carried out. Untreated women with C. trachomatis infection at the time of abortion had a cumulative risk of 72% of developing early and/or late PID, if observed for 24 months. This cumulative risk was significantly reduced to 8% if the C. trachomatis infection was treated at the time of the abortion. Screening for and treatment of C. trachomatis is warranted, especially in women <or = 25 years old, to avoid early and late-onset PID after induced first trimester abortion.

AB - After termination of a double-blind, randomized study on erythromycin in the prevention of post-abortion infection, 34 women (14 treated with erythromycin, 20 not treated with erythromycin) harbouring Chlamydia trachomatis were followed up within 6 weeks and again 2 to 24 months after the abortion in order to detect an early- and late-onset pelvic inflammatory disease (PID). For statistical analysis survival analysis by Kaplan-Meir estimates and Mantel-Cox test were carried out. Untreated women with C. trachomatis infection at the time of abortion had a cumulative risk of 72% of developing early and/or late PID, if observed for 24 months. This cumulative risk was significantly reduced to 8% if the C. trachomatis infection was treated at the time of the abortion. Screening for and treatment of C. trachomatis is warranted, especially in women <or = 25 years old, to avoid early and late-onset PID after induced first trimester abortion.

KW - Abortion, Induced

KW - Chlamydia Infections

KW - Chlamydia trachomatis

KW - Double-Blind Method

KW - Erythromycin

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Pelvic Inflammatory Disease

KW - Pregnancy

KW - Pregnancy Complications, Infectious

KW - Pregnancy Trimester, First

KW - Proportional Hazards Models

KW - Risk Factors

KW - Survival Analysis

KW - Time Factors

KW - Uterine Cervical Diseases

M3 - Journal article

C2 - 8002083

SN - 0300-8126

VL - 22

SP - 242

EP - 246

JO - Therapies

JF - Therapies

IS - 4

ER -