Abstract
After termination of a double-blind, randomized study on erythromycin in the prevention of post-abortion infection, 34 women (14 treated with erythromycin, 20 not treated with erythromycin) harbouring Chlamydia trachomatis were followed up within 6 weeks and again 2 to 24 months after the abortion in order to detect an early- and late-onset pelvic inflammatory disease (PID). For statistical analysis survival analysis by Kaplan-Meir estimates and Mantel-Cox test were carried out. Untreated women with C. trachomatis infection at the time of abortion had a cumulative risk of 72% of developing early and/or late PID, if observed for 24 months. This cumulative risk was significantly reduced to 8% if the C. trachomatis infection was treated at the time of the abortion. Screening for and treatment of C. trachomatis is warranted, especially in women <or = 25 years old, to avoid early and late-onset PID after induced first trimester abortion.
| Original language | English |
|---|---|
| Journal | Infection: A Journal of Infectious Diseases |
| Volume | 22 |
| Issue number | 4 |
| Pages (from-to) | 242-6 |
| Number of pages | 5 |
| ISSN | 0300-8126 |
| Publication status | Published - 1994 |
Keywords
- Abortion, Induced
- Chlamydia Infections
- Chlamydia trachomatis
- Double-Blind Method
- Erythromycin
- Female
- Follow-Up Studies
- Humans
- Pelvic Inflammatory Disease
- Pregnancy
- Pregnancy Complications, Infectious
- Pregnancy Trimester, First
- Proportional Hazards Models
- Risk Factors
- Survival Analysis
- Time Factors
- Uterine Cervical Diseases