Covalent attachment of antagonists to the a7 nicotinic acetylcholine receptor: synthesis and reactivity of substituted maleimides

Joseph I Ambrus, Jill I Halliday, Nicholas Kanizaj, Nathan Absalom, Kasper Harpsøe, Thomas Balle, Mary Chebib, Malcolm D McLeod

10 Citationer (Scopus)

Abstract

The 3-methylmaleimide congeners of the natural product methyllycaconitine (MLA) and an analogue covalently attach to functional cysteine mutants of the α7 nicotinic acetylcholine receptor (nAChR).

OriginalsprogEngelsk
TidsskriftChemical Communications
Vol/bind48
Udgave nummer53
Sider (fra-til)6699-6701
Antal sider3
ISSN1359-7345
DOI
StatusUdgivet - 6 jun. 2012

Fingeraftryk

Dyk ned i forskningsemnerne om 'Covalent attachment of antagonists to the a7 nicotinic acetylcholine receptor: synthesis and reactivity of substituted maleimides'. Sammen danner de et unikt fingeraftryk.

Citationsformater