Analogues of [3H] chloramphenicol for photoaffinity labeling

V Leick; O Buchardt; Peter E. Nielsen

Analogues of [3H] chloramphenicol for photoaffinity labeling

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2 Citationer (Scopus)

Abstract

The synthesis of [3H]chloramphenicol and its erythro-diastereoisomer with specific activities of 1.25 Ci/mmol, and the further transformation of the [3H]chloramphenicol to a series of azido and diazo-substituted derivatives are described. The antibiotic activity of the compounds was considered insufficient for their use as photoaffinity labels.

Originalsprog	Engelsk
Tidsskrift	Hoppe-Seyler's Zeitschrift fur Physiologische Chemie
Vol/bind	360
Udgave nummer	6
Sider (fra-til)	721-4
Antal sider	4
ISSN	0018-4888
Status	Udgivet - jun. 1979

Citationsformater

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title = "Analogues of [3H] chloramphenicol for photoaffinity labeling",

abstract = "The synthesis of [3H]chloramphenicol and its erythro-diastereoisomer with specific activities of 1.25 Ci/mmol, and the further transformation of the [3H]chloramphenicol to a series of azido and diazo-substituted derivatives are described. The antibiotic activity of the compounds was considered insufficient for their use as photoaffinity labels.",

keywords = "Affinity Labels, Chemical Phenomena, Chemistry, Chloramphenicol/analogs & derivatives, Escherichia coli/drug effects, Isotope Labeling/methods, Ribosomes/drug effects, Tritium",

author = "V Leick and O Buchardt and Nielsen, {Peter E.}",

year = "1979",

month = jun,

language = "English",

volume = "360",

pages = "721--4",

journal = "Hoppe-Seyler's Zeitschrift fur Physiologische Chemie",

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TY - JOUR

T1 - Analogues of [3H] chloramphenicol for photoaffinity labeling

AU - Leick, V

AU - Buchardt, O

AU - Nielsen, Peter E.

PY - 1979/6

Y1 - 1979/6

N2 - The synthesis of [3H]chloramphenicol and its erythro-diastereoisomer with specific activities of 1.25 Ci/mmol, and the further transformation of the [3H]chloramphenicol to a series of azido and diazo-substituted derivatives are described. The antibiotic activity of the compounds was considered insufficient for their use as photoaffinity labels.

AB - The synthesis of [3H]chloramphenicol and its erythro-diastereoisomer with specific activities of 1.25 Ci/mmol, and the further transformation of the [3H]chloramphenicol to a series of azido and diazo-substituted derivatives are described. The antibiotic activity of the compounds was considered insufficient for their use as photoaffinity labels.

KW - Affinity Labels

KW - Chemical Phenomena

KW - Chemistry

KW - Chloramphenicol/analogs & derivatives

KW - Escherichia coli/drug effects

KW - Isotope Labeling/methods

KW - Ribosomes/drug effects

KW - Tritium

M3 - Journal article

C2 - 381142

SN - 0018-4888

VL - 360

SP - 721

EP - 724

JO - Hoppe-Seyler's Zeitschrift fur Physiologische Chemie

JF - Hoppe-Seyler's Zeitschrift fur Physiologische Chemie

IS - 6

ER -

Analogues of [3H] chloramphenicol for photoaffinity labeling

Abstract

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Citationsformater